頭部外傷とADHDの関係

【文献名】
著者名:Heather T Keenan et al. 
文献タイトル:Early head injury and attention deficit hyperactivity disorder: retrospective cohort study.
雑誌名・書籍名:BMJ 2008: 337 doi: 10.1136/bmj.a1984 .
発行年:Published 6 November 2008.

【要約】
<Objective> 
To explore the hypothesis that medically attended head injury in young children may be causal in the later development of attention deficit hyperactivity disorder (ADHD).

<Design>
Retrospective cohort study.

<Setting>
Health improvement network database (1988-2003), a longitudinal UK general practice dataset.
Participants All children registered in the database from birth until their 10th birthday.

<Main outcome measures> 
Risk of a child with a head injury before age 2 developing attention deficit hyperactivity disorder before age 10 compared with children with a burn injury before age 2 and children with neither a burn nor a head injury.

<Results>
Of the 62?088 children who comprised the cohort, 2782 (4.5%) had a head injury and 1116 (1.8%) had a burn injury. The risk of diagnosis of attention deficit hyperactivity disorder before 10 years of age after adjustment for sex, prematurity, socioeconomic status, and practice identification number was similar in the head injury (relative risk 1.9, 95% confidence interval 1.5 to 2.5) and burn injury groups (1.7, 1.2 to 2.5) compared with all other children.

開催日】
2012年5月2日












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