{"id":1025,"date":"2016-03-16T17:22:06","date_gmt":"2016-03-16T08:22:06","guid":{"rendered":"http:\/\/www.hcfm.jp\/journal\/?p=1025"},"modified":"2016-03-16T17:22:06","modified_gmt":"2016-03-16T08:22:06","slug":"ppi%e3%81%8c%e9%ab%98%e9%bd%a2%e8%80%85%e3%81%ae%e8%aa%8d%e7%9f%a5%e7%97%87%e3%83%aa%e3%82%b9%e3%82%af%e3%82%92%e4%b8%8a%e6%98%87%e3%81%95%e3%81%9b%e3%82%8b%e5%8f%af%e8%83%bd%e6%80%a7","status":"publish","type":"post","link":"https:\/\/www.hcfm.jp\/journal\/?p=1025","title":{"rendered":"PPI\u304c\u9ad8\u9f62\u8005\u306e\u8a8d\u77e5\u75c7\u30ea\u30b9\u30af\u3092\u4e0a\u6607\u3055\u305b\u308b\u53ef\u80fd\u6027"},"content":{"rendered":"<p>\uff0d\u6587\u732e\u540d\uff0d<br \/>\nWilly Gomm et al. Association of Proton Pump Inhibitors With Risk of dementia: A Pharmacoepidemiological Claims Data Analysis. 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class=\"alignright size-full wp-image-1026\" src=\"https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2016\/03\/\u5cf6\u7530\u5148\u751f\u56f3.png\" alt=\"\u5cf6\u7530\u5148\u751f\u56f3\" width=\"980\" height=\"325\" srcset=\"https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2016\/03\/\u5cf6\u7530\u5148\u751f\u56f3.png 980w, https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2016\/03\/\u5cf6\u7530\u5148\u751f\u56f3-300x99.png 300w\" sizes=\"auto, (max-width: 980px) 100vw, 980px\" \/><\/a><\/p>\n<p>\u3010\u7d50\u679c\u3011<br \/>\n\u3000\u5bfe\u8c61\u96c6\u56e3(Figure1)<br \/>\n\u3000\u3000\u30fb\u300cPPI\u5b9a\u671f\u5185\u670d\u7fa4\u300d\u306f2950\u4eba\u300cPPI\u975e\u5185\u670d\u7fa4\u300d\u306f70729\u4eba\u3000\uff08Table1\uff09<br \/>\n\u3000\u3000\u30fb<span style=\"color: #ff0000;\">PPI\u306e\u30cf\u30b6\u30fc\u30c9\u6bd4\u30001.44(95%CI 1.36-1.52)<\/span><br \/>\n<a href=\"https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2016\/03\/\u5cf6\u7530\u5148\u751f\u56f32.png\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-1027\" src=\"https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2016\/03\/\u5cf6\u7530\u5148\u751f\u56f32.png\" alt=\"\u5cf6\u7530\u5148\u751f\u56f32\" width=\"849\" height=\"319\" srcset=\"https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2016\/03\/\u5cf6\u7530\u5148\u751f\u56f32.png 849w, https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2016\/03\/\u5cf6\u7530\u5148\u751f\u56f32-300x113.png 300w\" sizes=\"auto, (max-width: 849px) 100vw, 849px\" \/><\/a><br \/>\n\u3000\u30b5\u30d6\u89e3\u6790<br \/>\n\u3000\u3000\u30aa\u30e1\u30d7\u30e9\u30be\u30fc\u30eb(\u30aa\u30e1\u30d7\u30e9\u30fc\u30eb\u00ae)\u3000\u3000 1.51(1.40-4.64)<br \/>\n\u3000\u3000\u30d1\u30f3\u30c8\u30d7\u30e9\u30be\u30fc\u30eb(\u56fd\u5185\u672a\u627f\u8a8d) \u3000\u3000\u30001.58(1.40-1.79)<br \/>\n\u3000\u3000\u30a8\u30bd\u30e1\u30d7\u30e9\u30be\u30fc\u30eb\uff08\u30cd\u30ad\u30b7\u30a6\u30e0\u00ae\uff09\u3000 2.12(1.82-2.47)<br \/>\n\u3010\u7814\u7a76\u306e\u9650\u754c\u3011<br \/>\n\u3000\u30fb\u4ed6\u306e\u65e2\u77e5\u306e\u8a8d\u77e5\u75c7\u306e\u5371\u967a\u56e0\u5b50(ApoE4\u3084\u6559\u80b2\u30ec\u30d9\u30eb)\u3068\u3044\u3046\u56e0\u5b50\u3092\u8abf\u6574\u3067\u304d\u3066\u3044\u306a\u3044\u3002<br \/>\n\u3000\u30fb\u8a8d\u77e5\u75c7\u306e\u75c5\u578b\u3092\u533a\u5225\u3057\u3066\u3044\u306a\u3044<br \/>\n\u3010\u7d50\u8ad6\u3011<br 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\/>\n\u3000\u30fbSTOPP:\uff1aH2RA\uff08\u9ad8\u9f62\u8005\u306b\u304a\u3044\u3066\u8a8d\u77e5\u6a5f\u80fd\u4f4e\u4e0b\u3001\u305b\u3093\u5984\u306e\u30ea\u30b9\u30af\u3042\u308b\u305f\u3081\u53ef\u80fd\u306a\u9650\u308a\u4f7f\u7528\u3092\u63a7\u3048\u308b\uff09<br \/>\n\u3000\u30fbSTART\uff1aPPI\u3000\uff08GERD\/NERD\u306b\u5bfe\u3057\u3066\u3002\u4f46\u3057\uff11\u5e74\u4ee5\u4e0a\u308f\u305f\u308b\u5e38\u7528\u91cf\u3092\u8d8a\u3048\u308b\u6295\u4e0e\u306f\u907f\u3051\u308b\uff09<\/p>\n<p>\u3010\u958b\u50ac\u65e5\u3011<br \/>\n2016\u5e743\u670816\u65e5\uff08\u6c34\uff09<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\uff0d\u6587\u732e\u540d\uff0d Willy Gomm et al. Association of Proton Pump Inhibitors With Risk of dementia: A Pharmacoepidemiological &hellip; <a href=\"https:\/\/www.hcfm.jp\/journal\/?p=1025\" class=\"more-link\">\u7d9a\u304d\u3092\u8aad\u3080 <span class=\"screen-reader-text\">PPI\u304c\u9ad8\u9f62\u8005\u306e\u8a8d\u77e5\u75c7\u30ea\u30b9\u30af\u3092\u4e0a\u6607\u3055\u305b\u308b\u53ef\u80fd\u6027<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[17],"tags":[],"class_list":["post-1025","post","type-post","status-publish","format-standard","hentry","category-17"],"_links":{"self":[{"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/posts\/1025","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1025"}],"version-history":[{"count":5,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/posts\/1025\/revisions"}],"predecessor-version":[{"id":1032,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/posts\/1025\/revisions\/1032"}],"wp:attachment":[{"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1025"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1025"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1025"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}