{"id":1091,"date":"2016-08-15T17:03:50","date_gmt":"2016-08-15T08:03:50","guid":{"rendered":"http:\/\/www.hcfm.jp\/journal\/?p=1091"},"modified":"2016-08-15T17:03:50","modified_gmt":"2016-08-15T08:03:50","slug":"%e3%80%90ebm%e3%81%ae%e5%ad%a6%e3%81%b3%e3%80%91%e5%b9%b4%e9%bd%a2%e5%88%a5%e3%81%ae%e9%aa%a8%e7%b2%97%e9%ac%86%e7%97%87%e8%96%ac%e3%81%ae%e5%8a%b9%e6%9e%9c","status":"publish","type":"post","link":"https:\/\/www.hcfm.jp\/journal\/?p=1091","title":{"rendered":"\u3010EBM\u306e\u5b66\u3073\u3011\u5e74\u9f62\u5225\u306e\u9aa8\u7c97\u9b06\u75c7\u85ac\u306e\u52b9\u679c"},"content":{"rendered":"<p><strong>STEP1\u3000\u81e8\u5e8a\u60a3\u8005\u306b\u5373\u3057\u305fPI(E)CO<\/strong><br \/>\n\u3010\u8a55\u4fa1\u3092\u884c\u3063\u305f\u65e5\u4ed8\u3011<br \/>\n\u30002016\u5e746\u670810\u65e5<br \/>\n\u3010\u81e8\u5e8a\u72b6\u6cc1\u306e\u30b5\u30de\u30ea\u30fc\u3011<br \/>\n\u300081\u6b73\u5973\u6027\u3000\u753a\u306b\u5728\u4f4f\u3067\u592b\u30682\u4eba\u66ae\u3089\u3057\u3002\u6628\u5e741\u6708\u306b\u8133\u6897\u585e\u3067\u4ed6\u9662\u5165\u9662\u6b74\u304c\u3042\u308a\u305d\u306e\u969b\u306b\u9aa8\u7c97\u9b06\u75c7\u3092\u6307\u6458\u3055\u308c\u3066\u3044\u308b\u3002(\u5927\u817f\u9aa8\u306e\u9aa8\u5bc6\u5ea6\u304cYAM\u306766%\u3068\u8a3a\u7642\u60c5\u5831\u63d0\u4f9b\u3042\u308a)\u3002<br \/>\n\u3000\u305d\u306e\u5f8c\u30d3\u30b9\u30db\u30b9\u30db\u30cd\u30fc\u30c8\u5185\u670d\u306b\u3064\u3044\u3066\u76f8\u8ac7\u304c\u3042\u3063\u305f\u3088\u3046\u3060\u304c\u5185\u670d\u3092\u5897\u3084\u3057\u305f\u304f\u306a\u3044\u3053\u3068\u3068\u3001\u526f\u4f5c\u7528\u306e\u5fc3\u914d\u3082\u3042\u308a\u7d4c\u904e\u89b3\u5bdf\u3068\u306a\u3063\u3066\u3044\u305f\u3002\u4eca\u5e74\u306e4\u6708\u306b\u518d\u5ea6\u9aa8\u5bc6\u5ea6\u3092\u6e2c\u5b9a(\u6a48\u9aa8\u3067YAM\u304c55%\u3001T-score\u304c-5.56)\u3002\u518d\u5ea6\u30d3\u30b9\u30db\u30b9\u30db\u30cd\u30fc\u30c8\u5185\u670d\u306e\u76f8\u8ac7\u3092\u3059\u308b\u304c\u3001\u904e\u53bb\u306e\u8ee2\u5012\u3082\u306a\u304f\u3084\u306f\u308a\u5185\u670d\u306e\u526f\u4f5c\u7528\u306b\u4e0d\u5b89\u304c\u3042\u308b\u3068\u3002\u73fe\u5728\u306f\u300c\u6bce\u65e5\u9aa8\u30b1\u30a2\u300d\u3068\u3044\u3046\u30ab\u30eb\u30b7\u30a6\u30e0\u98f2\u6599\u3092\u98f2\u3093\u3067\u3044\u308b\u3002\u6708\u984d\u306f5000\u5186\u7a0b\u5ea6\u3067\u3042\u308b\u3002<\/p>\n<p>\u3000\u65e2\u5f80:\u8133\u6897\u585e(\u30d7\u30e9\u30d3\u30c3\u30af\u30b9\u5185\u670d\u3057\u3066\u3044\u308b)\u3002<br \/>\n\u3000ADL:\u81ea\u7acb(\u6628\u5e74\u306e\u8133\u6897\u585e\u3067\u5de6\u534a\u8eab\u9ebb\u75fa\u304c\u3042\u3063\u305f\u304c\u3001\u4eca\u306f\u6756\u3082\u306a\u304f\u6b69\u884c\u53ef\u80fd\u3002\u307b\u307c\u6bce\u65e52\u6642\u9593\u30d1\u30fc\u30af\u30b4\u30eb\u30d5\u3092\u3057\u3066\u3044\u308b)\u3002<br \/>\n\u3000\u8a8d\u77e5\u6a5f\u80fd:\u554f\u984c\u306a\u3057\u3002<\/p>\n<p>\u3000\u9aa8\u6298\u306e\u30ea\u30b9\u30af\u3092\u8003\u3048\u308b\u3068BP\u5264\u3092\u98f2\u3093\u3060\u65b9\u304c\u826f\u3044\u3068\u306f\u601d\u3046\u304c\u5b9f\u969b\u306bBP\u5264\u306e\u30b3\u30f3\u30d7\u30e9\u30a4\u30a2\u30f3\u30b9\u3082\u826f\u304f\u306f\u306a\u304f\u3001\u672c\u4eba\u306e\u526f\u4f5c\u7528\u306e\u61f8\u5ff5\u3082\u308f\u304b\u308b\u3002\u4e00\u5ea6\u6587\u732e\u3092\u8aad\u3093\u3067\u8aac\u660e\u3057\u305f\u65b9\u304c\u7d0d\u5f97\u51fa\u6765\u308b\u306e\u3067\u306f\u306a\u3044\u304b\u3002\u300c\u6bce\u65e5\u9aa8\u30b1\u30a2\u300d\u306f\u3069\u3046\u3060\u308d\u3046\u304b?\u305f\u3060\u3053\u308c\u3092\u6bd4\u8f03\u3057\u305f\u8ad6\u6587\u306f\u306a\u3044\u3002<\/p>\n<p>\u3000P\uff1b80\u4ee3\u9589\u7d4c\u5f8c\u306eADL\u304c\u81ea\u7acb\u3057\u3066\u3044\u308b\u5973\u6027\u3067<br \/>\n\u3000I(E)\uff1b\u30d3\u30b9\u30db\u30b9\u30db\u30cd\u30fc\u30c8\u5185\u670d\u3057\u3066\u3044\u308b\u4eba<br \/>\n\u3000C\uff1b\u5185\u670d\u3057\u3066\u3044\u306a\u3044\u4eba\u3067<br \/>\n\u3000O\uff1b\u9aa8\u6298\u306e\u767a\u751f\u7387\u306b\u5dee\u304c\u3067\u308b\u304b?<\/p>\n<p><strong>STEP2\u3000\u691c\u7d22\u3057\u3066\u898b\u3064\u3051\u305f\u6587\u732e\u306e\u540d\u524d<\/strong><br \/>\n\u3010\u898b\u3064\u3051\u305f\u8ad6\u6587\u3011<br \/>\n\u691c\u7d22\u3057\u305f\u30a8\u30f3\u30b8\u30f3\uff1bup to date \u3067\u3000\u300c\u9aa8\u7c97\u9b06\u75c7\u3000\u6cbb\u7642\u300d\u3067\u691c\u7d22<br \/>\n\u300c\u9589\u7d4c\u5f8c\u5973\u6027\u306e\u9aa8\u7c97\u9b06\u75c7\u306e\u30de\u30cd\u30fc\u30b8\u30e1\u30f3\u30c8\u300d\u306b\u884c\u304d\u3064\u304d\u3001\u9ad8\u9f62\u8005\u306e\u30a2\u30ec\u30f3\u30c9\u30ed\u30cd\u30fc\u30c8\u306e\u8ad6\u6587\u3092\u691c\u7d22\u3002\u30b7\u30b9\u30c6\u30de\u30c6\u30a3\u30c3\u30af\u30ec\u30d3\u30e5\u30fc\u3067\u306f\u9069\u5207\u306a\u8ad6\u6587\u3082\u3042\u3063\u305f\u304c\u3001\u4eca\u56de\u306fRCT\u306e\u5b66\u3073\u3092\u6df1\u3081\u305f\u3044\u3068\u8003\u3048\u305f\u3002\u305d\u306e\u4e0a\u3067RCT\u3067\u306e\u9069\u5207\u306a\u8ad6\u6587\u306f\u898b\u3064\u3051\u3089\u308c\u306a\u304b\u3063\u305f\u306e\u3067Pub med\u304b\u3089similar articles\u3092\u691c\u7d22\u3057\u3066\u8ad6\u6587\u3092\u898b\u3064\u3051\u305f\u3002<br \/>\n\u898b\u3064\u3051\u305f\u8ad6\u6587\uff1bEffects of Alendronate on the Age-Specific incidence of Symptomatic Osteoporotic Fractures<\/p>\n<p><strong>STEP3\uff1b\u8ad6\u6587\u306e\u8a55\u4fa1<br \/>\nSTEP3-1.\u8ad6\u6587\u306ePECO\u306f\u60a3\u8005\u306ePECO\u3068\u5408\u81f4\u3059\u308b\u304b\uff1f<\/strong><br \/>\n\u3000P\uff1b\u9589\u7d4c\u5f8c2\u5e74\u4ee5\u4e0a\u7d4c\u904e\u3057\u305f\u9aa8\u7c97\u9b06\u75c7\u304c\u3042\u308b55-80\u6b73\u5973\u6027\u306e<br \/>\n\u3000I(E)\uff1b\u30a2\u30ec\u30f3\u30c9\u30ed\u30cd\u30fc\u30c8\u5185\u670d\u7fa4\u3068<br \/>\n\u3000C\uff1b\u30d7\u30e9\u30bb\u30dc\u7fa4\u3067<br \/>\n\u3000O\uff1b\u5e74\u4ee3\u6bce\u3067\u9aa8\u6298\u4e88\u9632\u306e\u52b9\u679c\u304c\u5909\u308f\u308b\u304b?<br \/>\n\u3000\u2192\u60a3\u8005\u306ePECO\u3068\u3000(\u5408\u81f4\u3059\u308b\u3000\u30fb\u3000<strong>\u591a\u5c11\u7570\u306a\u308b\u304cOK<\/strong>\u3000\u30fb\u3000\u5927\u304d\u304f\u7570\u306a\u308b\u305f\u3081\u4e0d\u9069\u5207)<\/p>\n<p><strong>STEP3-2\u3000\u8ad6\u6587\u306e\u7814\u7a76\u30c7\u30b6\u30a4\u30f3\u306e\u8a55\u4fa1\uff1b\u5185\u7684\u59a5\u5f53\u6027\u306e\u8a55\u4fa1<\/strong><br \/>\n\u2460\u7814\u7a76\u65b9\u6cd5\u304cRCT\u306b\u306a\u3063\u3066\u3044\u308b\u304b\uff1f\u96a0\u853d\u5316\u3068\u76f2\u691c\u5316\u306f\u3055\u308c\u3066\u3044\u308b\u304b\uff1f<br \/>\n\u3000\u2192\u30e9\u30f3\u30c0\u30e0\u5272\u308a\u4ed8\u3051\u304c\u3000\uff08\u3000<span style=\"text-decoration: underline;\"><strong>\u3055\u308c\u3066\u3044\u308b<\/strong><\/span>\u3000\u30fb\u3000\u3000\u3055\u308c\u3066\u3044\u306a\u3044\u3000\uff09<br \/>\n\u3000\u2192\u96a0\u853d\u5316\u304c\u3000\u3000\u3000\u3000\u3000\u3000\uff08\u3000\u3055\u308c\u3066\u3044\u308b\u3000\u30fb\u3000\u3000\u3055\u308c\u3066\u3044\u306a\u3044\u3000\u30fb\u3000<span style=\"text-decoration: underline;\"><strong>\u8a18\u8f09\u306a\u3057<\/strong><\/span>\uff09<br \/>\n\u3000\u2192\u76f2\u691c\u5316\u304c\u3000\u3000\u3000\u3000\u3000\u3000\uff08\u3000<span style=\"text-decoration: underline;\"><strong>\u3055\u308c\u3066\u3044\u308b<\/strong><\/span>\u3000\u30fb\u3000\u3000\u3055\u308c\u3066\u3044\u306a\u3044\u3000\uff09<br \/>\n\u5b9f\u969b\u306eTable\u3067\u4ecb\u5165\u7fa4\u3068\u5bfe\u7167\u7fa4\u306f\u540c\u3058\u3088\u3046\u306a\u96c6\u56e3\u306b\u306a\u3063\u3066\u3044\u308b\u304b\uff1f<br \/>\n\u3000\u2192\uff08\u3000<span style=\"text-decoration: underline;\"><strong>\u306a\u3063\u3066\u3044\u308b<\/strong><\/span>\u3000\u30fb\u3000\u306a\u3063\u3066\u3044\u306a\u3044\uff09<br \/>\n\u3000\u3000\u3069\u3046\u7570\u306a\u308b\u304b\uff1f\uff1aTable1\u3067\u60a3\u8005\u306e\u30ad\u30e3\u30e9\u30af\u30bf\u30fc\u306f\u6574\u3063\u3066\u3044\u308b\u304c\u3001\u305d\u308c\u3092table2\u306b\u3057\u305f\u6642\u70b9\u3067\u4e16\u4ee3\u6bce\u306e\u5c64\u306b\u308f\u3051\u3089\u308c\u3066\u3057\u307e\u3046\u306e\u3067\u3001\u4ecb\u5165\u7fa4\u3068\u5bfe\u7167\u7fa4\u304c\u540c\u3058\u304b\u3069\u3046\u304b\u4e0d\u660e<br \/>\n\u2461 \u89e3\u6790\u65b9\u6cd5\u306fITT(intention to treat)\u304b\uff1f<br \/>\n\u3000\u2192ITT\u304c\u3000\uff08<span style=\"text-decoration: underline;\"><strong>\u3055\u308c\u3066\u3044\u308b<\/strong><\/span>\u3000\u3000\u30fb\u3000\u3000\u3055\u308c\u3066\u3044\u306a\u3044\uff09<\/p>\n<p><strong>STEP3-3\u3000\u8ad6\u6587\u3067\u898b\u3044\u3060\u3055\u308c\u305f\u7d50\u679c\u306e\u8a55\u4fa1<\/strong><br \/>\nOutcome\u306b\u3064\u3044\u3066\u3001\u4ee5\u4e0b\u306e\u5024\u3092\u78ba\u8a8d\u3059\u308b<br \/>\n\u3000Table 2\u3092\u53c2\u7167.\u3053\u3053\u304b\u3089cox proportional hazards\u306b\u30c7\u30fc\u30bf\u3092\u5f53\u3066\u306f\u3081\u305f\u306e\u304cFig.1(P\u5024\u3001RR)\u3001Fig.2(\u6700\u5e74\u5c11\u3001\u6700\u9ad8\u9f62\u306e\u4e16\u4ee3\u5225\u306eARR)<br \/>\n\u3000\u3000Table2<br \/>\n\u3000\u3000\u80a1\u95a2\u7bc0\/\u5927\u817f\u9aa8\u3000P: 0.43\u3000\u690e\u4f53\u3000P:0.47\u3000\u624b\u9996\u3000P:0.36\u3000\u8907\u5408\u3000P:0.53<br \/>\n<a href=\"https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2016\/08\/\u5b89\u9054\u5148\u751f\u56f3.jpg\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2016\/08\/\u5b89\u9054\u5148\u751f\u56f3-300x214.jpg\" alt=\"\u5b89\u9054\u5148\u751f\u56f3\" width=\"300\" height=\"214\" class=\"aligncenter size-medium wp-image-1094\" srcset=\"https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2016\/08\/\u5b89\u9054\u5148\u751f\u56f3-300x214.jpg 300w, https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2016\/08\/\u5b89\u9054\u5148\u751f\u56f3.jpg 884w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a><br \/>\n\u3010\u2460 \u6cbb\u7642\u52b9\u679c\u306e\u6709\u7121\uff1b P\u5024\u3092\u78ba\u8a8d\u3059\u308b\u3011<br \/>\n\u3000Table2\u306eP\u5024\u306f0.05\u4ee5\u4e0a\u3067\u3042\u308a\u52b9\u679c\u306b\u5dee\u304c\u51fa\u306a\u3044\u3002Figure1\u306eP\u5024\u306f0.05\u672a\u6e80\u3067\u3042\u308a\u52b9\u679c\u306b\u5dee\u304c\u3042\u308b\u3002<\/p>\n<p>\u3010\u2461\u6cbb\u7642\u52b9\u679c\u306e\u5927\u304d\u3055\uff1b\u6bd4\u306e\u6307\u6a19\u3068\u5dee\u306e\u6307\u6a19\u3092\u78ba\u8a8d\u3059\u308b\u3011<br \/>\n\u3000\u4e0a\u8a18\u8868\u3092\u53c2\u7167\u3002ARR\u306fFig2\u304b\u3089\u51fa\u3057\u3066\u305d\u3053\u304b\u3089NNT\u3082\u51fa\u3057\u3066\u3044\u308b\u3002\u9ad8\u9f62\u8005\u306e\u65b9\u304cARR\u3001NNT\u304c\u9ad8\u304f\u306a\u3063\u3066\u3044\u308b\u3002<\/p>\n<p>\u3010\u2462\u6cbb\u7642\u52b9\u679c\u306e\u3086\u3089\u304e\uff1b\u4fe1\u983c\u533a\u9593\u3092\u78ba\u8a8d\u3059\u308b\u3011<br \/>\n\u3000Fig1\u3067\u306f\u3069\u308c\u308295%Cl\u304c1\u3092\u542b\u3093\u3067\u3044\u306a\u3044\u3002<\/p>\n<p>STEP4\u3000\u60a3\u8005\u3078\u306e\u9069\u7528<br \/>\n\u3010\u2460\u8ad6\u6587\u306e\u60a3\u8005\u3068\u3001\u76ee\u306e\u524d\u306e\u60a3\u8005\u304c\u3001\u7d50\u679c\u304c\u9069\u7528\u3067\u304d\u306a\u3044\u307b\u3069\u7570\u306a\u3063\u3066\u3044\u306a\u3044\u304b\uff1f\u3011<br \/>\n\u3000Table 1\u3092\u53c2\u7167\u3001\u9589\u7d4c\u5f8c\u5973\u6027\u3001\u9ad8\u9f62\u8005\u3001\u9aa8\u7c97\u9b06\u75c7\u306f\u4e00\u81f4\u3057\u3066\u3044\u308b\u3002\u5bfe\u8c61\u8005\u306e\u5e74\u9f62\u304c\u5e73\u5747\u3057\u306610\u6b73\u307b\u3069\u82e5\u3044\u3002\u767d\u4eba\u306e\u7814\u7a76\u3002\u30a2\u30ec\u30f3\u30c9\u30ed\u30cd\u30fc\u30c8\u306f2\u5e74\u5f8c\u304b\u30895\u338e\u304b\u308910mg\u306b\u5909\u66f4\u306b\u306a\u3063\u3066\u3044\u308b\u306e\u3067\u65e5\u672c\u3067\u306f\u884c\u308f\u306a\u3044\u65b9\u6cd5\u3002T-score\u304c\u8170\u690e\u3068\u5927\u817f\u9aa8\u3067\u20102.0~-2.5\u3060\u304c\u5b9f\u969b\u306f\u6a48\u9aa8\u3067\u20105.56\u3067\u3042\u3063\u305f\u3002<br \/>\n\u30fb\u5185\u7684\u59a5\u5f53\u6027\u306e\u554f\u984c\u70b9\u306f\uff1f(STEP3\u306e\u7d50\u679c\u306e\u30b5\u30de\u30ea\u30fc)<br \/>\n\u3000\u2192\u96a0\u853d\u5316\u3055\u308c\u3066\u3044\u306a\u3044\u90e8\u5206\u304c\u554f\u984c\u3002\u9aa8\u6298\u306e\u4e88\u9632\u3068\u3044\u3046\u30a2\u30a6\u30c8\u30ab\u30e0\u306f\u554f\u984c\u306a\u3044\u3002<br \/>\n\u3010\u2461\u6cbb\u7642\u305d\u306e\u3082\u306e\u306f\u5fe0\u5b9f\u306b\u5b9f\u884c\u53ef\u80fd\u304b\uff1f\u3011<br \/>\n\u3000\u9ad8\u9f62\u592b\u5a66\u3067\u3042\u308b\u304c\u8a8d\u77e5\u9762\u306f\u554f\u984c\u306a\u304f\u670d\u85ac\u30b3\u30f3\u30d7\u30e9\u30a4\u30a2\u30f3\u30b9\u306f\u826f\u597d\u3002\u5185\u670d\u306f\u53ef\u80fd\u3002\u305f\u3060\u3057\u526f\u4f5c\u7528\u3068\u30b3\u30f3\u30d7\u30e9\u30a4\u30a2\u30f3\u30b9\u306b\u3064\u3044\u3066\u306e\u8aac\u660e\u306f\u5fc5\u8981\u3002(\u670d\u85ac\u56de\u6570\u306b\u3064\u3044\u3066\u3042\u3089\u304b\u3058\u3081\u3082\u30d7\u30e9\u30f3\u3068\u3057\u3066\u63d0\u793a\u3057\u305f\u65b9\u304c\u826f\u3055\u305d\u3046)\u3002<br \/>\n\u3010\u2462\u91cd\u8981\u306a\u30a2\u30a6\u30c8\u30ab\u30e0\u306f\u30b3\u30b9\u30c8\u3084\u5bb3\u3092\u542b\u3081\u3066\u5168\u3066\u8a55\u4fa1\u3055\u308c\u305f\u304b\uff1f\u3011<br \/>\n\u3000\u30b3\u30b9\u30c8\u306b\u95a2\u3057\u3066\u306f105\u5186\u00d730\u65e5=3150\u5186\u3068\u6bce\u65e5\u9aa8\u30b1\u30a2\u3088\u308a\u5b89\u3044\u3002\u9aa8\u6298\u4e88\u9632\u306e\u30a2\u30a6\u30c8\u30ab\u30e0\u306f\u3042\u308b\u3002<br \/>\n\u3010\u2463\u60a3\u8005\u306e\u8003\u3048\u30fb\u55dc\u597d\u306f\u3069\u3046\u306a\u306e\u304b\uff1f\u3011<br \/>\n\u3000\u30fb\u3053\u308c\u307e\u3067\u306e\u305d\u306e\u6cbb\u7642\u306b\u5bfe\u3059\u308b\u7d4c\u9a13\u306f\u3069\u3046\u304b\uff1f<br \/>\n\u3000\u3000\u2192\u30d3\u30b9\u30db\u30b9\u30db\u30cd\u30fc\u30c8\u3092\u4eca\u307e\u3067\u65b0\u898f\u3067\u51e6\u65b9\u3057\u305f\u3053\u3068\u306f\u306a\u3044\u3002<br \/>\n\u3000\u30fb\u81ea\u5206\u306e\u719f\u9054\u5ea6\u304b\u3089\u5b9f\u884c\u306f\u53ef\u80fd\u3060\u308d\u3046\u304b\uff1f<br \/>\n\u3000\u3000\u2192\u672c\u4eba\u3068\u526f\u4f5c\u7528\u306b\u3064\u3044\u3066\u3042\u3089\u304b\u3058\u3081\u8a71\u3057\u5408\u3044\u306a\u304c\u3089\u8a08\u753b\u3092\u305f\u3066\u3066\u884c\u3048\u3070\u5927\u4e08\u592b\u3068\u8003\u3048\u308b\u3002<br \/>\n\u3000\u30fbillness\/context\u306e\u89b3\u70b9\u304b\u3089\u306f\u6cbb\u7642\u306f\u884c\u3046\u3079\u304d\u304b\uff1f\u3042\u308b\u3044\u306fillness\/context\u3092\u66f4\u306b\u78ba\u8a8d\u3059\u308b\u3079\u304d\u304b\uff1f<br \/>\n\u3000\u3000\u2192\u672c\u4eba\u306b\u3068\u3063\u3066\u306e\u5065\u5eb7\u611f\u306f\u8cb7\u3044\u7269\u306b\u884c\u3063\u305f\u308a\u3001\u75c5\u9662\u306b\u6765\u305f\u308a\u3059\u308b\u3053\u3068\u3002\u4ef2\u9593\u3068\u30d1\u30fc\u30af\u30b4\u30eb\u30d5\u3092\u3059\u308b\u3053\u3068\u3002\u9ad8\u9f62\u8005\u72ec\u5c45\u3067\u9aa8\u6298\u306e\u30ea\u30b9\u30af\u3082\u9ad8\u3044\u3068\u8003\u3048\u308b\u3068\u3001\u4eca\u56de\u306e\u7d50\u679c\u304b\u3089\u3082\u8aac\u660e\u3057\u3066\u6cbb\u7642\u306f\u884c\u3046\u3079\u304d\u3068\u601d\u3046\u3002\u305f\u3060\u306a\u305c\u5185\u670d\u3092\u3057\u305f\u304f\u306a\u3044\u304b\u306f\u3082\u3046\u5c11\u3057\u6df1\u304f\u805e\u304f\u5fc5\u8981\u306f\u3042\u308b\u3002<\/p>\n<p>\u3010\u958b\u50ac\u65e5\u3011<br \/>\n2016\u5e747\u670813\u65e5\uff08\u6c34\uff09<\/p>\n","protected":false},"excerpt":{"rendered":"<p>STEP1\u3000\u81e8\u5e8a\u60a3\u8005\u306b\u5373\u3057\u305fPI(E)CO \u3010\u8a55\u4fa1\u3092\u884c\u3063\u305f\u65e5\u4ed8\u3011 \u30002016\u5e746\u670810\u65e5 \u3010\u81e8\u5e8a\u72b6\u6cc1\u306e\u30b5\u30de\u30ea\u30fc\u3011 \u300081\u6b73\u5973\u6027\u3000\u753a\u306b\u5728\u4f4f\u3067\u592b\u30682\u4eba\u66ae\u3089\u3057\u3002\u6628\u5e741\u6708\u306b\u8133\u6897\u585e\u3067\u4ed6\u9662\u5165\u9662\u6b74\u304c\u3042\u308a\u305d\u306e\u969b\u306b\u9aa8\u7c97\u9b06\u75c7\u3092\u6307\u6458\u3055\u308c\u3066\u3044\u308b &hellip; <a href=\"https:\/\/www.hcfm.jp\/journal\/?p=1091\" class=\"more-link\">\u7d9a\u304d\u3092\u8aad\u3080 <span class=\"screen-reader-text\">\u3010EBM\u306e\u5b66\u3073\u3011\u5e74\u9f62\u5225\u306e\u9aa8\u7c97\u9b06\u75c7\u85ac\u306e\u52b9\u679c<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1,11],"tags":[],"class_list":["post-1091","post","type-post","status-publish","format-standard","hentry","category-1","category-11"],"_links":{"self":[{"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/posts\/1091","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1091"}],"version-history":[{"count":3,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/posts\/1091\/revisions"}],"predecessor-version":[{"id":1096,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/posts\/1091\/revisions\/1096"}],"wp:attachment":[{"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1091"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1091"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1091"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}