\u2015\u6587\u732e\u540d\u2015
\nAlexander C Ford, et al. Helicobacter pylori eradication therapy to prevent gastric cancer in healthy asymptomatic infected individuals: systematic review and meta-analysis of randomized controlled trials. BMJ. 2014 May 20:348:g3174.<\/p>\n
\u2015\u8981\u7d04\u2015
\n\u3010\u76ee\u7684\u3011
\n\u3000\u5065\u5e38\u8005\u306e\u7121\u75c7\u5019\u6027\u30d4\u30ed\u30ea\u83cc\u611f\u67d3\u306b\u9664\u83cc\u6cbb\u7642\u3092\u884c\u3046\u3068\u3001\u30d7\u30e9\u30bb\u30dc\u3084\u7121\u6cbb\u7642\u3068\u6bd4\u8f03\u3057\u3001\u80c3\u764c\u767a\u75c7\u3092\u6e1b\u3089\u305b\u308b\u304b\u3002<\/p>\n
\u3010\u65b9\u6cd5\u3011
\n\u3000Systematic review and meta-analysis of RCT<\/p>\n
\u3010\u60c5\u5831\u6e90\u3011
\n\u3000Medline\u3001Embase\u3001Cochrane\uff08\uff5e2013\u5e7412\u6708\uff09\u3001\u4f1a\u8b70\u9332\uff082001\uff5e2013\u5e74\uff09\u3001\u95a2\u9023\u7814\u7a76\u306e\u53c2\u8003\u6587\u732e\u3002\u8a00\u8a9e\u306b\u3088\u308b\u5236\u9650\u306a\u3057\u30022\u4eba\u306e\u72ec\u7acb\u3057\u305f\u7814\u7a76\u8005\u3067\u8a55\u4fa1\u3057\u3001\u4e0d\u4e00\u81f4\u3042\u308c\u3070\u5408\u610f\u5f62\u6210\u3002<\/p>\n
\u3010\u63a1\u7528\u57fa\u6e96\u3011
\n\u3000\u5065\u5e38\u8005\u306e\u7121\u75c7\u5019\u6027\u30d4\u30ed\u30ea\u83cc\u611f\u67d3\u306b\u5bfe\u3059\u308b\u9664\u83cc\u6cbb\u7642\u306e\u80c3\u764c\u767a\u75c7\u6e1b\u5c11\u52b9\u679c\u3092\u8abf\u3079\u305fRCT\u3002\u9664\u83cc\u6cbb\u7642\u306f\u6700\u4f4e\uff17\u65e5\u9593\u3002\u5bfe\u7167\u7fa4\u306f\u30d7\u30e9\u30bb\u30dc\u307e\u305f\u306f\u7121\u6cbb\u7642\u3002\u8ffd\u8de1\u671f\u9593\u304c\u6700\u4f4e2\u5e74\u9593\u3002<\/p>\n
\u3010\u4e3b\u8981\u30a2\u30a6\u30c8\u30ab\u30e0\u3011
\n\u3000\u9664\u83cc\u6cbb\u7642\u306b\u3088\u308b\u80c3\u764c\u767a\u75c7\u6e1b\u5c11\u52b9\u679c\uff08RR\uff1arelative risk\uff09<\/p>\n
\u3010\u7d50\u679c\u3011
\n\u30001560\u6587\u732e\u304c\u691c\u7d22\u3055\u308c6\u4ef6\u306eRCT\u3092\u63a1\u7528\u3001Random effects model\u3067\u7d50\u679c\u304c\u7d71\u5408\u3055\u308c\u305f\u3002\u9664\u83cc\u6cbb\u7642\u7fa43294\u540d\u4e2d51\u540d\uff081.6%\uff09\u3001\u5bfe\u7167\u7fa43203\u540d\u4e2d76\u540d\uff082.4%\uff09\u306b\u80c3\u764c\u304c\u767a\u75c7\u3057\u3001RR0.66\uff0895%\u4fe1\u983c\u533a\u95930.46-0.95\uff09\u3067\u6709\u610f\u5dee\u304c\u3042\u3063\u305f\u3002\u7814\u7a76\u9593\u306e\u7570\u8cea\u6027\u306a\u3057\uff08I2\uff1d0%\u3001P\uff1d0.60\uff09\u3002\u9664\u83cc\u6cbb\u7642\u52b9\u679c\u304c\u751f\u6daf\u7d9a\u304f\u3068\u4eee\u5b9a\u3059\u308b\u3068\u3001NNT16\uff08\u4e2d\u56fd\u4eba\u7537\u6027\uff09\u304b\u3089NNT246\uff08\u30a2\u30e1\u30ea\u30ab\u4eba\u5973\u6027\uff09\u3068\u4eba\u7a2e\u6027\u5225\u306b\u3088\u3063\u3066\u5e45\u3042\u308a\u3002\u306a\u304a\u3001\u65e5\u672c\u4eba\u7537\u6027NNT16\u3001\u65e5\u672c\u4eba\u5973\u6027NNT23\u3067\u3042\u3063\u305f\u3002<\/p>\n
\u3010\u9650\u754c\u3011
\n\u3000\u59a5\u5f53\u6027\u306e\u9ad8\u3044RCT\uff08Cochrane handbook\u306b\u3088\u308b\u8a55\u4fa1\uff09\u306f6\u4ef6\u4e2d3\u4ef6\u306e\u307f\u3002\u9664\u83cc\u30ec\u30b8\u30e1\u30f3\u304c\u7814\u7a76\u9593\u3067\u7570\u306a\u308b\u3002\u6709\u5bb3\u4e8b\u8c61\u306e\u691c\u8a0e\u306f\u3055\u308c\u3066\u3044\u306a\u3044\u3002<\/p>\n
\u3010\u7d50\u8ad6\u3011
\n\u3000\u30a2\u30b8\u30a2\u4eba\u5065\u5e38\u8005\u306e\u7121\u75c7\u5019\u6027\u30d4\u30ed\u30ea\u83cc\u611f\u67d3\u306b\u5bfe\u3059\u308b\u9664\u83cc\u6cbb\u7642\u306f\u3001\u80c3\u764c\u767a\u75c7\u4e88\u9632\u52b9\u679c\u3042\u308a\u3002<\/p>\n
\u3010\u958b\u50ac\u65e5\u3011
\n2015\u5e747\u670822\u65e5\uff08\u6c34\uff09<\/p>\n","protected":false},"excerpt":{"rendered":"