{"id":1255,"date":"2017-02-06T15:41:29","date_gmt":"2017-02-06T06:41:29","guid":{"rendered":"http:\/\/www.hcfm.jp\/journal\/?p=1255"},"modified":"2017-02-06T15:41:29","modified_gmt":"2017-02-06T06:41:29","slug":"%e3%80%90ebm%e3%81%ae%e5%ad%a6%e3%81%b3%e3%80%91%e6%80%a5%e6%80%a7%e4%b8%8b%e7%97%a2%e7%97%87%e3%81%ab%e5%af%be%e3%81%99%e3%82%8b%e6%95%b4%e8%85%b8%e5%89%a4%e3%81%ae%e5%8a%b9%e6%9e%9c","status":"publish","type":"post","link":"https:\/\/www.hcfm.jp\/journal\/?p=1255","title":{"rendered":"\u3010EBM\u306e\u5b66\u3073\u3011\u6025\u6027\u4e0b\u75e2\u75c7\u306b\u5bfe\u3059\u308b\u6574\u8178\u5264\u306e\u52b9\u679c"},"content":{"rendered":"<p><strong>STEP1\u3000\u81e8\u5e8a\u60a3\u8005\u306b\u5373\u3057\u305fPI(E)CO<\/strong><br \/>\n\u3010\u8a55\u4fa1\u3092\u884c\u3063\u305f\u65e5\u4ed8\u3011<br \/>\n\u30002016\u5e7412\u670823\u65e5<br \/>\n\u3010\u81e8\u5e8a\u72b6\u6cc1\u306e\u30b5\u30de\u30ea\u30fc\u3011<br \/>\n\u300011\u6b73\u3001\u7537\u5150\u3002<br \/>\n\u3000\u53d7\u8a3a1\u65e5\u524d\u304b\u3089\u8179\u75db\u3092\u81ea\u899a\u3057\u3001\u305d\u306e\u5f8c\u8907\u6570\u56de\u306e\u4e0b\u75e2\u3042\u308a\u3002<br \/>\n\u3000\u4fbf\u306e\u6027\u72b6\u306f\u6c34\u69d8\u6027\u3067\u3001\u8840\u4fbf\u3084\u9ed2\u8272\u4fbf\u306f\u306a\u3044\u3002\u305d\u306e\u4ed6\u3001\u60aa\u5fc3\u30fb\u5614\u5410\u30fb\u767a\u71b1\u306a\u3069\u306e\u968f\u4f34\u75c7\u72b6\u306f\u306a\u3057\u3002<br \/>\n\u3000\u5468\u56f2\u6d41\u884c\u6b74\u306f\u306a\u304f\u3001\u751f\u3082\u306e\u306a\u3069\u306e\u98df\u4e8b\u6442\u53d6\u306f\u306a\u3044\u3002<br \/>\n\u3000\u80c3\u8178\u708e\u3068\u8a3a\u65ad\u3057\u3001\u6574\u8178\u5264\u3092\u51e6\u65b9\u3059\u308b\u65e8\u3092\u4f1d\u3048\u305f\u3068\u3053\u308d\u3001\u540c\u4f34\u3057\u305f\u6bcd\u89aa\u304b\u3089\u300c\u3053\u308c(\u6574\u8178\u5264)\u3092\u98f2\u3080\u3068\u3001\u4e0b\u75e2\u306f\u3059\u3050\u826f\u304f\u306a\u308a\u307e\u3059\u304b\uff1f\u300d\u300c\u30e8\u30fc\u30b0\u30eb\u30c8\u3082\u52b9\u679c\u3042\u308a\u307e\u3059\u304b\uff1f\u300d\u3068\u8cea\u554f\u304c\u3042\u3063\u305f\u3002<\/p>\n<p>\u3000\u3000P\uff1b\u5c0f\u5150\u306e\u6025\u6027\u80c3\u8178\u708e\u306b\u5bfe\u3057<br \/>\n\u3000\u3000I(E)\uff1b\u6574\u8178\u5264\u3092\u51e6\u65b9\u3057\u305f\u5834\u5408 \/ \u4e73\u88fd\u54c1\u3092\u6442\u53d6\u3057\u305f\u3068\u304d\u3068<br \/>\n\u3000\u3000C\uff1b\u5185\u670d\u3057\u306a\u3044 \/ \u6442\u53d6\u3057\u306a\u3044\u3068\u304d\u3068\u6bd4\u8f03\u3057\u3066<br \/>\n\u3000\u3000O\uff1a\u4e0b\u75e2\u75c7\u72b6\u306e\u671f\u9593\u77ed\u7e2e\u306b\u3064\u306a\u304c\u308b\u304b<\/p>\n<p><strong>STEP2\u3000\u691c\u7d22\u3057\u3066\u898b\u3064\u3051\u305f\u6587\u732e\u306e\u540d\u524d<\/strong><br \/>\n\u3010\u898b\u3064\u3051\u305f\u8ad6\u6587\u3011<br \/>\n\u3000Probiotics for treatment of acute diarrhoea in children randomised clinical trial of five different preparations<\/p>\n<p><strong>STEP3\uff1b\u8ad6\u6587\u306e\u8a55\u4fa1<\/strong><br \/>\n<strong>STEP3-1.\u8ad6\u6587\u306ePECO\u306f\u60a3\u8005\u306ePECO\u3068\u5408\u81f4\u3059\u308b\u304b\uff1f<\/strong><br \/>\n\u3000P\uff1b\u5c0f\u5150(3-36\u30f6\u6708)\u306e\u6025\u6027\u4e0b\u75e2\u75c7\u306b\u304a\u3044\u3066<br \/>\n\u3000I(E)\uff1b5\u7a2e\u985e\u306e\u6574\u8178\u5264\u3092\u8ffd\u52a0\u3057\u305f\u7fa4\u3068<br \/>\n\u3000C\uff1b\u7d4c\u53e3\u88dc\u6db2\u7642\u6cd5(ORT)\u306e\u307f\u306e\u7fa4\u3092\u6bd4\u3079<br \/>\n\u3000O\uff1b\u4e0b\u75e2\u306e\u671f\u9593\u3084\u6392\u4fbf\u56de\u6570\u304c\u7e2e\u5c0f\u3059\u308b\u304b<br \/>\n\u2192\u60a3\u8005\u306ePECO\u3068\u3000(\u5408\u81f4\u3059\u308b\u3000\u30fb\u3000<span style=\"text-decoration: underline;\"><strong>\u591a\u5c11\u7570\u306a\u308b\u304cOK<\/strong><\/span>\u3000\u30fb\u3000\u5927\u304d\u304f\u7570\u306a\u308b\u305f\u3081\u4e0d\u9069\u5207)<\/p>\n<p><strong>STEP3-2\u3000\u8ad6\u6587\u306e\u7814\u7a76\u30c7\u30b6\u30a4\u30f3\u306e\u8a55\u4fa1\uff1b\u5185\u7684\u59a5\u5f53\u6027\u306e\u8a55\u4fa1<\/strong><br \/>\n\u2460\u7814\u7a76\u65b9\u6cd5\u304cRCT\u306b\u306a\u3063\u3066\u3044\u308b\u304b\uff1f\u96a0\u853d\u5316\u3068\u76f2\u691c\u5316\u306f\u3055\u308c\u3066\u3044\u308b\u304b\uff1f<br \/>\n\u3000\u2192\u30e9\u30f3\u30c0\u30e0\u5272\u308a\u4ed8\u3051\u304c\u3000\uff08\u3000<span style=\"text-decoration: underline;\"><strong>\u3055\u308c\u3066\u3044\u308b<\/strong><\/span>\u3000\u30fb\u3000\u3000\u3055\u308c\u3066\u3044\u306a\u3044\u3000<br \/>\n\u3000\u2192\u96a0\u853d\u5316\u304c\uff08\u3000<span style=\"text-decoration: underline;\"><strong>\u3055\u308c\u3066\u3044\u308b<\/strong><\/span>\u3000\u30fb\u3000\u3000\u3055\u308c\u3066\u3044\u306a\u3044\u3000\u30fb\u3000\u4e0d\u660e \uff09<br \/>\n\u3000\u2192\u76f2\u691c\u5316\u304c\uff08\u3000<span style=\"text-decoration: underline;\"><strong>\u3055\u308c\u3066\u3044\u308b<\/strong><\/span>\u3000\u30fb\u3000\u4e00\u90e8\u3055\u308c\u3066\u3044\u308b\u3000\u30fb\u3000\u3000\u3055\u308c\u3066\u3044\u306a\u3044\u3000\u30fb\u8a18\u8f09\u306a\u3057\u3000\uff09<br \/>\n\u5b9f\u969b\u306eTable\u3067\u4ecb\u5165\u7fa4\u3068\u5bfe\u7167\u7fa4\u306f\u540c\u3058\u3088\u3046\u306a\u96c6\u56e3\u306b\u306a\u3063\u3066\u3044\u308b\u304b\uff1f<br \/>\n\u3000\u2192\uff08\u3000<span style=\"text-decoration: underline;\"><strong>\u306a\u3063\u3066\u3044\u308b<\/strong><\/span>\u3000\u30fb\u3000\u306a\u3063\u3066\u3044\u306a\u3044\u3000\u30fb\u3000\u8a18\u8f09\u306a\u3057\u3000\uff09<br \/>\n\u2461 \u89e3\u6790\u65b9\u6cd5\u306fITT(intention to treat)\u304b\uff1f<br \/>\n\u3000\u2192ITT\u304c\uff08 <span style=\"text-decoration: underline;\"><strong>\u3055\u308c\u3066\u3044\u308b<\/strong><\/span>\u3000\u30fb\u3000\u3055\u308c\u3066\u3044\u306a\u3044 \uff09<\/p>\n<p><strong>STEP3-3\u3000\u8ad6\u6587\u3067\u898b\u3044\u3060\u3055\u308c\u305f\u7d50\u679c\u306e\u8a55\u4fa1<\/strong><br \/>\nOutcome\u306b\u3064\u3044\u3066\u3001\u4ee5\u4e0b\u306e\u5024\u3092\u78ba\u8a8d\u3059\u308b<br \/>\n\u3010\u2460 \u6cbb\u7642\u52b9\u679c\u306e\u6709\u7121\uff1b P\u5024\u3092\u78ba\u8a8d\u3059\u308b\u3011<br \/>\n<a href=\"https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2017\/02\/\u3072\u308d\u3080\u5148\u751f\u56f3\u2460.png\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-1256\" src=\"https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2017\/02\/\u3072\u308d\u3080\u5148\u751f\u56f3\u2460.png\" alt=\"\u3072\u308d\u3080\u5148\u751f\u56f3\u2460\" width=\"676\" height=\"228\" srcset=\"https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2017\/02\/\u3072\u308d\u3080\u5148\u751f\u56f3\u2460.png 676w, https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2017\/02\/\u3072\u308d\u3080\u5148\u751f\u56f3\u2460-300x101.png 300w\" sizes=\"auto, (max-width: 676px) 100vw, 676px\" \/><\/a><\/p>\n<p><a href=\"https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2017\/02\/\u3072\u308d\u3080\u5148\u751f\u56f3\u2461.png\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-large wp-image-1257\" src=\"https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2017\/02\/\u3072\u308d\u3080\u5148\u751f\u56f3\u2461.png\" alt=\"\u3072\u308d\u3080\u5148\u751f\u56f3\u2461\" width=\"640\" height=\"228\" srcset=\"https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2017\/02\/\u3072\u308d\u3080\u5148\u751f\u56f3\u2461.png 677w, https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2017\/02\/\u3072\u308d\u3080\u5148\u751f\u56f3\u2461-300x107.png 300w\" sizes=\"auto, (max-width: 640px) 100vw, 640px\" \/><\/a><\/p>\n<p><a href=\"https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2017\/02\/\u3072\u308d\u3080\u5148\u751f\u56f3\u2462.png\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-large wp-image-1258\" src=\"https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2017\/02\/\u3072\u308d\u3080\u5148\u751f\u56f3\u2462.png\" alt=\"\u3072\u308d\u3080\u5148\u751f\u56f3\u2462\" width=\"640\" height=\"238\" srcset=\"https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2017\/02\/\u3072\u308d\u3080\u5148\u751f\u56f3\u2462.png 667w, https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2017\/02\/\u3072\u308d\u3080\u5148\u751f\u56f3\u2462-300x112.png 300w\" sizes=\"auto, (max-width: 640px) 100vw, 640px\" \/><\/a><\/p>\n<p><a href=\"https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2017\/02\/\u3072\u308d\u3080\u5148\u751f\u56f3\u2463.png\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-large wp-image-1259\" src=\"https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2017\/02\/\u3072\u308d\u3080\u5148\u751f\u56f3\u2463.png\" alt=\"\u3072\u308d\u3080\u5148\u751f\u56f3\u2463\" width=\"640\" height=\"213\" srcset=\"https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2017\/02\/\u3072\u308d\u3080\u5148\u751f\u56f3\u2463.png 668w, https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2017\/02\/\u3072\u308d\u3080\u5148\u751f\u56f3\u2463-300x100.png 300w\" sizes=\"auto, (max-width: 640px) 100vw, 640px\" \/><\/a><\/p>\n<p>\u3010\u2461\u6cbb\u7642\u52b9\u679c\u306e\u5927\u304d\u3055\uff1b\u6bd4\u306e\u6307\u6a19\u3068\u5dee\u306e\u6307\u6a19\u3092\u78ba\u8a8d\u3059\u308b\u3011<br \/>\n\u25cfRR(\u3042\u308b\u3044\u306fHR\u30fbOR)\u3092\u78ba\u8a8d\u3059\u308b<br \/>\n\u25cfARR\u3068NNT\u3092\u8a08\u7b97\u3059\u308b<br \/>\n\u203bP\u5024\u3067\u6709\u610f\u5dee\u304c\u51fa\u305f\u3082\u306e\u306b\u3064\u3044\u3066\u8a08\u7b97<br \/>\n\u2192\u6cbb\u7642\u52b9\u679c\u306f\u8a08\u7b97\u3067\u304d\u306a\u3044<\/p>\n<p>\u3010\u2462\u6cbb\u7642\u52b9\u679c\u306e\u3086\u3089\u304e\uff1b\u4fe1\u983c\u533a\u9593\u3092\u78ba\u8a8d\u3059\u308b\u3011<br \/>\n\u2192\u2460\u53c2\u7167<\/p>\n<p>STEP4\u3000\u60a3\u8005\u3078\u306e\u9069\u7528<br \/>\n\u3010\u2460\u8ad6\u6587\u306e\u60a3\u8005\u3068\u3001\u76ee\u306e\u524d\u306e\u60a3\u8005\u304c\u3001\u7d50\u679c\u304c\u9069\u7528\u3067\u304d\u306a\u3044\u307b\u3069\u7570\u306a\u3063\u3066\u3044\u306a\u3044\u304b\uff1f\u3011<br \/>\n\u3000\u9664\u5916\u57fa\u6e96\u3067\u3042\u308b\u6804\u990a\u5931\u8abf\u3084\u91cd\u7be4\u306a\u8131\u6c34\u3001\u4f75\u5b58\u3059\u308b\u611f\u67d3\u75c7(\u9ac4\u819c\u708e\u3001\u80ba\u708e\u3001sepsis)\u3001\u514d\u75ab\u4e0d\u5168\u3001\u98df\u7269\u30a2\u30ec\u30eb\u30ae\u30fc\u3001\u7814\u7a76\u958b\u59cb3\u9031\u4ee5\u5185\u306e\u6297\u83cc\u85ac\u3084\u6b62\u75e2\u5264\u306e\u4f7f\u7528\u7b49\u306f\u306a\u3044\u3002<br \/>\n\u3000\u4f46\u3057\u3001\u75c7\u4f8b\u306f11\u6b73\u3068\u3044\u3046\u5b66\u7ae5\u671f\u3067\u3001\u7814\u7a76\u3067\u306f3\u304b\u6708\uff5e3\u6b73\u3068\u3044\u3063\u305f\u4e73\u5e7c\u5150\u304c\u5bfe\u8c61\u3067\u3042\u308a\u3001\u5bfe\u8c61\u5e74\u9f62\u304b\u3089\u5916\u308c\u3066\u3044\u308b\u3002\u5b66\u7ae5\u671f\u3068\u4e73\u5e7c\u5150\u671f\u306e\u6025\u6027\u4e0b\u75e2\u75c7\u306b\u304a\u3051\u308b\u767a\u75c7\u7d4c\u904e\u3084\u81e8\u5e8a\u7d4c\u904e\u3001\u6cbb\u7652\u904e\u7a0b\u306a\u3069\u306b\u3064\u3044\u3066\u306e\u5dee\u7570\u3092\u306f\u3063\u304d\u308a\u3068\u3055\u305b\u308b\u3053\u3068\u304c\u3067\u304d\u306a\u304b\u3063\u305f\u305f\u3081\u3001\u3053\u306e\u70b9\u306b\u304a\u3044\u3066\u672c\u75c7\u4f8b\u3078\u306e\u9069\u5fdc\u304c\u53ef\u80fd\u304b\u306f\u4e0d\u660e\u3067\u3042\u308b\u3002<\/p>\n<p>\u30fb\u5185\u7684\u59a5\u5f53\u6027\u306e\u554f\u984c\u70b9\u306f\uff1f<br \/>\n\u3000\u7814\u7a76\u306f\u30e9\u30f3\u30c0\u30e0\u5316\u3001\u96a0\u853d\u5316\u3001\u76f2\u691c\u5316\u3055\u308c\u3066\u3044\u308b\u3002\u5272\u4ed8\u3055\u308c\u305f6\u3064\u306e\u7fa4\u306e\u7279\u5fb4\u304c\u8a18\u8f09\u3055\u308c\u3066\u304a\u308a\u3001\u6bd4\u8f03\u304c\u306a\u3055\u308c\u3066\u3044\u308b\u3002<\/p>\n<p>\u3010\u2461\u6cbb\u7642\u305d\u306e\u3082\u306e\u306f\u5fe0\u5b9f\u306b\u5b9f\u884c\u53ef\u80fd\u304b\uff1f\u3011<br \/>\n<a href=\"https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2017\/02\/\u3072\u308d\u3080\u5148\u751f\u56f3\u2464.png\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-1260\" src=\"https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2017\/02\/\u3072\u308d\u3080\u5148\u751f\u56f3\u2464.png\" alt=\"\u3072\u308d\u3080\u5148\u751f\u56f3\u2464\" width=\"960\" height=\"720\" srcset=\"https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2017\/02\/\u3072\u308d\u3080\u5148\u751f\u56f3\u2464.png 960w, https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2017\/02\/\u3072\u308d\u3080\u5148\u751f\u56f3\u2464-300x225.png 300w\" sizes=\"auto, (max-width: 960px) 100vw, 960px\" \/><\/a><\/p>\n<p>\u3000\u4e0a\u8a18\u8868\u306f\u3042\u308b\u8a3a\u7642\u6240\u3067\u306e\u6574\u8178\u5264\u306e\u63a1\u7528\u85ac\u3060\u304c\u3001\u3069\u306e\u6574\u8178\u5264\u30826\u5186\u524d\u5f8c\u3067\u3042\u308a\u3001\u5185\u670d\u671f\u9593\u3082\u77ed\u671f\u9593\u3067\u5185\u670d\u7ba1\u7406\u306f\u89aa\u304c\u884c\u3046\u3053\u3068\u304c\u4e88\u60f3\u3055\u308c\u3001\u5185\u670d\u306f\u5b9f\u884c\u53ef\u80fd\u3068\u8003\u3048\u3089\u308c\u308b\u3002<br \/>\n\u3000\u6295\u85ac\u91cf\u306b\u3064\u3044\u3066\u306f\u3001\u6574\u8178\u5264\u306e\u83cc\u7a2e\u306e\u8868\u8a18\u304c<br \/>\n\u3000\u3000\u65e5\u672c\uff1a\u88fd\u52641\u9320\/1g\u4e2d\u306b\u3007\u3007\u83cc\u25b3mg\u542b\u307e\u308c\u3066\u3044\u308b<br \/>\n\u3000\u3000\u6d77\u5916\uff1a\u3007\u3007\u83cc\u304c10\u25b3CFU\/dose(twice daily)<br \/>\n\u3068\u3044\u3063\u305f\u3088\u3046\u306b\u8a18\u8f09\u306b\u76f8\u9055\u70b9\u304c\u3042\u308a\u3001\u6295\u85ac\u91cf\u306e\u63db\u7b97\u306f\u56f0\u96e3\u3067\u3042\u308b\u3002<br \/>\n\u3000Group5\u306f4\u7a2e\u985e\u306e\u83cc\u7a2e\u304c\u542b\u307e\u308c\u3066\u3044\u308b\u306e\u3067\u3001\u8907\u6570\u306e\u83cc\u7a2e\u306b\u3088\u308a\u4eca\u56de\u306e\u7d50\u679c\u304c\u51fa\u305f\u306e\u304b\u3001\u307e\u305f\u306f\u8907\u6570\u306e\u83cc\u7a2e\u306e\u3046\u3061\u3069\u308c\u304c\u52b9\u679c\u3092\u767a\u63ee\u3057\u305f\u306e\u304b\u306f\u4e0d\u660e\u3067\u3042\u308b\u3002<\/p>\n<p>\u3010\u2462\u91cd\u8981\u306a\u30a2\u30a6\u30c8\u30ab\u30e0\u306f\u30b3\u30b9\u30c8\u3084\u5bb3\u3092\u542b\u3081\u3066\u5168\u3066\u8a55\u4fa1\u3055\u308c\u305f\u304b\uff1f\u3011<br 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loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-1261\" src=\"https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2017\/02\/\u3072\u308d\u3080\u5148\u751f\u56f3\u2465.png\" alt=\"\u3072\u308d\u3080\u5148\u751f\u56f3\u2465\" width=\"960\" height=\"720\" srcset=\"https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2017\/02\/\u3072\u308d\u3080\u5148\u751f\u56f3\u2465.png 960w, https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2017\/02\/\u3072\u308d\u3080\u5148\u751f\u56f3\u2465-300x225.png 300w\" sizes=\"auto, (max-width: 960px) 100vw, 960px\" \/><\/a><\/p>\n<p>\u203b\u30d3\u30aa\u30d5\u30a7\u30eb\u30df\u30f3\u300c\u9320\u300d\u300c\u6563\u300d\u306b\u3064\u3044\u3066<br \/>\n\u3000\u2192\u5264\u578b\u304c\u7570\u306a\u308b\u3068\u4f7f\u7528\u3055\u308c\u3066\u3044\u308b\u83cc\u7a2e\u304c\u7570\u306a\u308b\u5225\u306e\u85ac\u306b\u306a\u308b\u3002<br \/>\n\u3000 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\u3000\u4fbf\u306e\u6027\u72b6\u306f\u6c34\u69d8\u6027\u3067\u3001\u8840\u4fbf\u3084\u9ed2 &hellip; <a href=\"https:\/\/www.hcfm.jp\/journal\/?p=1255\" class=\"more-link\">\u7d9a\u304d\u3092\u8aad\u3080 <span class=\"screen-reader-text\">\u3010EBM\u306e\u5b66\u3073\u3011\u6025\u6027\u4e0b\u75e2\u75c7\u306b\u5bfe\u3059\u308b\u6574\u8178\u5264\u306e\u52b9\u679c<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[17],"tags":[],"class_list":["post-1255","post","type-post","status-publish","format-standard","hentry","category-17"],"_links":{"self":[{"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/posts\/1255","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1255"}],"version-history":[{"count":2,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/posts\/1255\/revisions"}],"predecessor-version":[{"id":1263,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/posts\/1255\/revisions\/1263"}],"wp:attachment":[{"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1255"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1255"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1255"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}