{"id":1321,"date":"2017-05-19T10:50:34","date_gmt":"2017-05-19T01:50:34","guid":{"rendered":"http:\/\/www.hcfm.jp\/journal\/?p=1321"},"modified":"2017-05-19T10:50:34","modified_gmt":"2017-05-19T01:50:34","slug":"%e6%84%9f%e6%9f%93%e3%82%92%e4%bc%b4%e3%81%a3%e3%81%9f%e5%b0%8f%e5%85%90%e6%b9%bf%e7%96%b9%e3%81%ab%e5%af%be%e3%81%99%e3%82%8b%e7%b5%8c%e5%8f%a3%e3%81%8a%e3%82%88%e3%81%b3%e5%a4%96%e7%94%a8%e6%8a%97","status":"publish","type":"post","link":"https:\/\/www.hcfm.jp\/journal\/?p=1321","title":{"rendered":"\u611f\u67d3\u3092\u4f34\u3063\u305f\u5c0f\u5150\u6e7f\u75b9\u306b\u5bfe\u3059\u308b\u7d4c\u53e3\u304a\u3088\u3073\u5916\u7528\u6297\u751f\u5264\u6cbb\u7642\u306e\u662f\u975e"},"content":{"rendered":"

\u2015\u6587\u732e\u540d\u2015
\nFrancis NA, Ridd MJ, Thomas-Jones E, et al. Oral and Topical Antibiotics for Clinically Infected Eczema in Children: A Pragmatic Randomized Controlled Trial in Ambulatory Care. Ann Fam Med. 2017;15(2):124-130. <\/p>\n

\u2015\u8981\u7d04\u2015
\nIntroduction<\/strong>
\n\u3000\u6e7f\u75b9\u306e\u3042\u308b\u60a3\u8005\u3067\u306f\u76ae\u819a\u304b\u308970\uff05\u306b\u9ec4\u8272\u30d6\u30c9\u30a6\u7403\u83cc\u304c\u691c\u51fa\u3055\u308c\u3001\u60aa\u5316\u306e\u969b\u306f\u5e83\u304f\u5916\u7528\u6297\u751f\u5264\u304c\u51e6\u65b9\u3055\u308c\u3066\u3044\u308b\u3002\u3057\u304b\u30572010\u5e74\u306e\u6e7f\u75b9\u3078\u306e\u6297\u751f\u5264\u52a0\u7642\u306b\u3064\u3044\u3066Cochrane review\u3067\u306e\u6700\u65b0\u60c5\u5831\u3067\u306f\u3001\u95a2\u9023\u7814\u7a76\u306e\u591a\u304f\u306f\u898f\u6a21\u304c\u5c0f\u3055\u304f\u3001\u8cea\u306b\u6b20\u3051\u3066\u3044\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3001\u8457\u8005\u306f\u6e7f\u75b9\u306e\u60aa\u5316\u3078\u6297\u751f\u5264\u304c\u4f7f\u7528\u3055\u308c\u308b\u3053\u3068\u306b\u7591\u554f\u3092\u62b1\u3044\u305f\u3002
\n\u3000\u305d\u306e\u305f\u3081\u81e8\u5e8a\u7684\u306b\u6e7f\u75b9\u306b\u611f\u67d3\u3092\u4f34\u3063\u305f\u3068\u5224\u65ad\u3055\u308c\u308b\u5c0f\u5150\u306b\u5bfe\u3057\u3066\u3001\u6a19\u6e96\u6cbb\u7642\u3067\u3042\u308b\u30b9\u30c6\u30ed\u30a4\u30c9\u5916\u7528\u306b\u8ffd\u52a0\u3057\u3066\u7d4c\u53e3\u3084\u5916\u7528\u6297\u751f\u5264\u3092\u6295\u4e0e\u3059\u308b\u3053\u3068\u304c\u6e7f\u75b9\u306e\u4e3b\u89b3\u7684\u306a\u91cd\u75c7\u5ea6\u3092\u8efd\u6e1b\u3059\u308b\u3046\u3048\u3067\u3088\u308a\u52b9\u679c\u7684\u304b\u3069\u3046\u304b\u3092\u5224\u65ad\u3059\u308b\u305f\u3081\u672c\u7814\u7a76\u3092\u5b9f\u65bd\u3057\u305f\u3002<\/p>\n

Method<\/strong>
\n\u3000\u82f1\u56fd\u306e\u5916\u6765\u8a3a\u7642\u306e\u30bb\u30c3\u30c6\u30a3\u30f3\u30b0\u30673\u7fa4\u9593\u306e\u76f2\u691c\u5316\u30e9\u30f3\u30c0\u30e0\u5316\u6bd4\u8f03\u8a66\u9a13\u3092\u884c\u3063\u305f\u3002\u611f\u67d3\u5fb4\u5019\u3092\u4f34\u3046\u6e7f\u75b9\u306e\u3042\u308b3\u304b\u6708\u304b\u30898\u6b73\u306e\u5c0f\u5150\u60a3\u8005\u306b\u5bfe\u3057\u3001\u7d4c\u53e3\u3068\u5916\u7528\u306e\u507d\u85ac\uff08\u5bfe\u7167\u7fa4\uff09\u3001\u5916\u7528\u306e\u507d\u85ac\u3068\u7d4c\u53e3\u6297\u751f\u5264\u3001\u5916\u7528\u6297\u751f\u5264\u3068\u7d4c\u53e3\u306e\u507d\u85ac\u306e\u3044\u305a\u308c\u304b\u3092\u305d\u308c\u305e\u308c\u7121\u4f5c\u70ba\u306b1\u9031\u9593\u51e6\u65b9\u3092\u53d7\u3051\u305f\u3002\u305f\u3060\u3057potent\u3082\u3057\u304f\u306fvery potent\u5916\u7528\u30b9\u30c6\u30ed\u30a4\u30c9\u3084\u6297\u751f\u5264\u306e\u6700\u8fd1\u306e\u670d\u7528\u6b74\u3001\u91cd\u75c7\u611f\u67d3\u306e\u5fb4\u5019\u3092\u8a8d\u3081\u308b\u3001\u307e\u305f\u91cd\u7be4\u306a\u4f75\u5b58\u75be\u60a3\u3092\u3082\u3064\u4e8b\u4f8b\u306f\u9664\u5916\u3055\u308c\u305f\u30021\u6b21\u30a2\u30a6\u30c8\u30ab\u30e0\u3092\u6e7f\u75b9\u306e\u4e3b\u89b3\u7684\u91cd\u75c7\u5ea6\u5c3a\u5ea6\u3067\u3042\u308bPatient Oriented Eczema Measure\uff08\u4ee5\u4e0b\u3001POEM\uff09\u3068\u3057\u30012\u9031\u9593\u5f8c\u306ePOEM\u30b9\u30b3\u30a2\u3092\u5171\u5206\u6563\u5206\u6790\u3092\u7528\u3044\u6bd4\u8f03\u3057\u305f\u3002
\n\u3000\u30b5\u30f3\u30d7\u30eb\u30b5\u30a4\u30ba\u306f\u03b1\uff1d0.025\u300190\uff05\u306e\u691c\u51fa\u529b\u3068\u3057\u305f\u3068\u304d\u300120\uff05\u304c\u8ffd\u8de1\u304b\u3089\u3082\u308c\u308b\u3053\u3068\u3092\u60f3\u5b9a\u3057517\u4eba\u3068\u8a2d\u8a08\u3057\u305f\u30022014\u5e744\u6708\u6642\u70b9\u3067\u306e\u89e3\u6790\u7d50\u679c\u304b\u3089\u306f225\u4eba\u304c\u5fc5\u8981\u3068\u3055\u308c\u305f\u3002<\/p>\n

Result<\/strong>
\n\u30002013\u5e747\u6708\u304b\u30892014\u5e7412\u6708\u307e\u306794\u306e\u533b\u7642\u6a5f\u95a2\u304c\u53c2\u52a0\u3057\u300133\u304b\u6240\u30671\u540d\u4ee5\u4e0a\u306e\u53c2\u52a0\u8005\u304c\u5f97\u3089\u308c\u305f\u3002\u76ee\u6a19\u306e\u30b5\u30f3\u30d7\u30eb\u30b5\u30a4\u30ba\u306b\u6e80\u305f\u306a\u304b\u3063\u305f\u3082\u306e\u306e113\u540d\u306e\u53c2\u52a0\u8005\u304c\u7121\u4f5c\u70ba\u5272\u308a\u4ed8\u3051\u3055\u308c\u305f\u30023\u7fa4\u9593\u3067\u60a3\u8005\u80cc\u666f\u306b\u6709\u610f\u306a\u9055\u3044\u306f\u306a\u304b\u3063\u305f\uff08Table\uff11\uff09\u3002\u7814\u7a76\u958b\u59cb\u6642\u306e\u5e73\u5747POEM\u30b9\u30b3\u30a2\u306f\u5bfe\u7167\u7fa4\u306713.4\uff08\u6a19\u6e96\u504f\u5dee5.1\uff09\u3001\u7d4c\u53e3\u6297\u751f\u5264\u7fa4\u306714.6\uff085.3\uff09\u3001\u5916\u7528\u6297\u751f\u5264\u7fa4\u306716.9\uff085.5\uff09\u3067\u3042\u308a\u30012\u9031\u5f8c\u306f\u305d\u308c\u305e\u308c6.2\uff086.0\uff09\u30018.3\uff087.3\uff09\u30019.3\uff086.2\uff09\u3067\u3042\u308a\u3001\u6297\u751f\u5264\u306e\u52b9\u679c\u306f\u7d4c\u53e3\u5264\u30671.5\uff0895\uff05\u4fe1\u983c\u533a\u9593\uff1a-1.4-4..4\uff09\u3001\u5916\u7528\u5264\u30671.5\uff08-1.6-4.5\uff09\u3068\u6709\u610f\u5dee\u3092\u8a8d\u3081\u306a\u304b\u3063\u305f\uff08Table\uff12\uff09\u3002
\n\"\u4e0a\u91ce\u5148\u751f\u56f3\uff11\"<\/a><\/p>\n

Discussion<\/strong>
\n\u3000\u672c\u7814\u7a76\u3067\u306f\u30d7\u30e9\u30a4\u30de\u30ea\u30b1\u30a2\u3067\u5c0f\u5150\u306e\u611f\u67d3\u3092\u4f34\u3063\u305f\u6e7f\u75b9\u306fmild\u304b\u3089moderate\u306e\u30b9\u30c6\u30ed\u30a4\u30c9\u5916\u7528\u3067\u901f\u3084\u304b\u306b\u6539\u5584\u3057\u3001\u7d4c\u53e3\u3084\u5916\u7528\u6297\u751f\u5264\u306e\u8ffd\u52a0\u306f\u7121\u76ca\u3067\u3042\u308b\u3053\u3068\u304c\u308f\u304b\u3063\u305f\u3002\u5f53\u521d\u8a2d\u5b9a\u3057\u305f\u30b5\u30f3\u30d7\u30eb\u30b5\u30a4\u30ba\u306b\u306f\u6e80\u305f\u306a\u304b\u3063\u305f\u3082\u306e\u306e\u3001\u6297\u751f\u5264\u4f7f\u7528\u306e\u4ecb\u5165\u52b9\u679c\u306e\u4fe1\u983c\u533a\u9593\u4e0b\u9650\uff08-1.4\u3068-1.6\uff09\u3067\u3082\u81e8\u5e8a\u4e0a\u91cd\u8981\u306a\u6700\u5c0f\u306ePOEM\u306e\u5dee\u306b\u6e80\u305f\u305a\u3001\u3053\u308c\u3089\u306e\u7d50\u679c\u306f\u5076\u7136\u306b\u3088\u308b\u3082\u306e\u3067\u306f\u306a\u3044\u3068\u8003\u3048\u308b\u3002\u307e\u305f\uff12\u6b21\u5206\u6790\u3067\u3082\u4e00\u8cab\u3057\u3066\u540c\u69d8\u306e\u50be\u5411\u304c\u307f\u3089\u308c\u305f\u3002
\n\u3000\u672c\u7814\u7a76\u306f\u611f\u67d3\u3092\u4f34\u3063\u305f\u6e7f\u75b9\u306b\u5bfe\u3057\u3066\u7d4c\u53e3\u304a\u3088\u3073\u5916\u7528\u6297\u751f\u5264\u306e\u52b9\u679c\u3092\u8a55\u4fa1\u3057\u305f\u6700\u5927\u306e\u7814\u7a76\u3067\u3042\u308b\u3002\u611f\u67d3\u3092\u4f34\u3063\u305f\u6e7f\u75b9\u306f\u660e\u78ba\u306a\u5b9a\u7fa9\u306f\u5b58\u5728\u3057\u306a\u3044\u305f\u3081\u3001\u5b9f\u969b\u7684\u306a\u9069\u683c\u57fa\u6e96\u3092\u8a2d\u3051\u305f\u3002\u9ec4\u8272\u30d6\u30c9\u30a6\u7403\u83cc\u306f\u958b\u59cb\u6642\u306770\uff05\u306b\u3057\u304b\u8a8d\u3081\u306a\u304b\u3063\u305f\u304c\u3001\u3059\u3079\u3066\u306e\u60a3\u8005\u3067\u533b\u5e2b\u306f\u611f\u67d3\u3092\u8d77\u3053\u3057\u3066\u3044\u308b\u3068\u8003\u3048\u3066\u304a\u308a\u3001\u73fe\u5728\u306e\u8a3a\u7642\u306b\u76f4\u63a5\u53cd\u6620\u3055\u308c\u308b\u7d50\u679c\u3067\u306f\u306a\u3044\u3060\u308d\u3046\u304b\u3002
\n\"\u4e0a\u91ce\u5148\u751f\u56f3\uff12\"<\/a><\/p>\n

\u3010\u958b\u50ac\u65e5\u3011
\n\u30002017\u5e745\u670817\u65e5\uff08\u6c34\uff09<\/p>\n","protected":false},"excerpt":{"rendered":"

\u2015\u6587\u732e\u540d\u2015 Francis NA, Ridd MJ, Thomas-Jones E, et al. Oral and Topical Antibiotics for Clinically Infected Eczema … \u7d9a\u304d\u3092\u8aad\u3080 \u611f\u67d3\u3092\u4f34\u3063\u305f\u5c0f\u5150\u6e7f\u75b9\u306b\u5bfe\u3059\u308b\u7d4c\u53e3\u304a\u3088\u3073\u5916\u7528\u6297\u751f\u5264\u6cbb\u7642\u306e\u662f\u975e<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[17],"tags":[],"class_list":["post-1321","post","type-post","status-publish","format-standard","hentry","category-17"],"_links":{"self":[{"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/posts\/1321","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1321"}],"version-history":[{"count":1,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/posts\/1321\/revisions"}],"predecessor-version":[{"id":1324,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/posts\/1321\/revisions\/1324"}],"wp:attachment":[{"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1321"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1321"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1321"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}