{"id":1623,"date":"2019-02-06T13:42:46","date_gmt":"2019-02-06T04:42:46","guid":{"rendered":"http:\/\/www.hcfm.jp\/journal\/?p=1623"},"modified":"2019-02-06T13:42:46","modified_gmt":"2019-02-06T04:42:46","slug":"%e7%a6%81%e7%85%99%e3%81%ab%e3%82%88%e3%82%8b%e4%bd%93%e9%87%8d%e5%a2%97%e5%8a%a0%e3%81%ae%e5%bd%b1%e9%9f%bf","status":"publish","type":"post","link":"https:\/\/www.hcfm.jp\/journal\/?p=1623","title":{"rendered":"\u7981\u7159\u306b\u3088\u308b\u4f53\u91cd\u5897\u52a0\u306e\u5f71\u97ff"},"content":{"rendered":"<p>\u2015\u6587\u732e\u540d\u2015<br \/>\nYang Hu. et al. Smoking Cessation, Weight Change, Type 2 Diabetes, and Mortality. N Engl J Med 2018; 379:623-632.<\/p>\n<p>\u2015\u8981\u7d04\u2015<br \/>\nIntroduction\uff1a<br \/>\n\u7981\u7159\u5f8c\u306e\u4f53\u91cd\u5897\u52a0\u306b\u3088\u3063\u3066\u3001\u7981\u7159\u306b\u3088\u308b\u5065\u5eb7\u4e0a\u306e\u5229\u76ca\u304c\u6e1b\u5c11\u3059\u308b\u304b\u3069\u3046\u304b\u306f\u660e\u3089\u304b\u306b\u3055\u308c\u3066\u3044\u306a\u3044\u3002<br \/>\nMethod\uff1a<br \/>\n\u7c73\u56fd\u306e\u7537\u5973\u3092\u5bfe\u8c61\u3068\u3057\u305f3\u3064\u306e\u30b3\u30db\u30fc\u30c8\u7814\u7a76\u3067\u3001\u7981\u7159\u3057\u305f\u4eba\u3092\u7279\u5b9a\u3057\u3001\u7981\u7159\u72b6\u6cc1\u3068\u4f53\u91cd\u306e\u5909\u5316\u3092\u524d\u5411\u304d\u306b\u8a55\u4fa1\u3057\u305f\u3002\u7981\u7159\u8005\u306b\u304a\u3051\u308b2\u578b\u7cd6\u5c3f\u75c5\u30fb\u5fc3\u8840\u7ba1\u75be\u60a3\u306b\u3088\u308b\u6b7b\u4ea1\u30fb\u5168\u6b7b\u56e0\u6b7b\u4ea1\u306e\u30ea\u30b9\u30af\u3092\u7981\u7159\u5f8c\u306e\u4f53\u91cd\u306e\u5909\u5316\u91cf\u5225\u306b\u8a55\u4fa1\u3057\u305f\u3002<br \/>\nResults\uff1a<br \/>\n<a href=\"https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2019\/02\/201902\u8cb4\u5cf61.png\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft size-large wp-image-1624\" src=\"https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2019\/02\/201902\u8cb4\u5cf61-1024x1007.png\" alt=\"201902\u8cb4\u5cf61\" width=\"640\" height=\"629\" srcset=\"https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2019\/02\/201902\u8cb4\u5cf61-1024x1007.png 1024w, https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2019\/02\/201902\u8cb4\u5cf61-300x295.png 300w, https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2019\/02\/201902\u8cb4\u5cf61.png 1288w\" sizes=\"auto, (max-width: 640px) 100vw, 640px\" \/><\/a><br \/>\n\u6700\u8fd1\uff08\u7981\u71592\u301c6\u5e74\u9593\uff09\u7981\u7159\u3057\u305f\u4eba\u306f\u3001\u73fe\u5728\u306e\u55ab\u7159\u8005\u3088\u308a\u3082\u30012\u578b\u7cd6\u5c3f\u75c5\u306e\u30ea\u30b9\u30af\u304c\u9ad8\u304f\u3001HR\uff1a1.22\u3000\uff0895\uff05CI\uff1a1.12-1.32\uff09\u3002<br \/>\n\u3057\u304b\u3057\u3001\u5fc3\u8840\u7ba1\u75be\u60a3\u306b\u3088\u308b\u6b7b\u4ea1\u306eHR\u306f\u73fe\u5728\u306e\u55ab\u7159\u8005\u3068\u6bd4\u8f03\u3057\u3066\u3001\u4f53\u91cd\u5897\u52a0\u306e\u7a0b\u5ea6\u3092\u554f\u308f\u305a\u6700\u8fd1\u306e\u55ab\u7159\u8005\u304a\u3088\u3073\u9577\u671f\u9593\uff08\uff1e6\u5e74\u9593)\u306e\u7981\u7159\u8005\u3068\u3082\u306b\u4f4e\u4e0b\u3057\u305f\u3002<br \/>\n2\u578b\u7cd6\u5c3f\u75c5\u306e\u30ea\u30b9\u30af\u306f\u3001\u4f53\u91cd\u306e\u5897\u52a0\u91cf\u306b\u6b63\u6bd4\u4f8b\u3057\u3066\u304a\u308a\u3001\u4f53\u91cd\u5897\u52a0\u304c\u306a\u3044\u30fb0.1\u301c5kg\u5897\u3067\u306f\u30ea\u30b9\u30af\u4e0a\u6607\u306e\u6709\u610f\u5dee\u306f\u306a\u304b\u3063\u305f\u3002<br \/>\n\u7981\u7159\u3057\u305f\u4eba\u3067\u306f\u3001\u7981\u7159\u5f8c\u306e\u4f53\u91cd\u5909\u5316\u306b\u304b\u304b\u308f\u3089\u305a\u3001\u6b7b\u4ea1\u7387\u306b\u4e00\u6642\u7684\u306a\u4e0a\u6607\u306f\u8a8d\u3081\u3089\u308c\u306a\u304b\u3063\u305f\u3002\u73fe\u5728\u306e\u55ab\u7159\u8005\u3068\u6bd4\u8f03\u3057\u3066\u3001\u5fc3\u8840\u7ba1\u75be\u60a3\u306b\u3088\u308b\u6b7b\u4ea1\u306eHR\u306f\u3001\u6700\u8fd1\u306e\u7981\u7159\u8005\u306e\u3046\u3061\u3001\u4f53\u91cd\u304c\u5897\u52a0\u3057\u306a\u304b\u3063\u305f\u7fa4\u30670.69\uff0895\uff05CI\uff1a0.54\uff5e0.88\uff09\u30010.1\uff5e5.0 kg\u5897\u52a0\u306e\u7fa4\u30670.47\uff0895\uff05CI\uff1a0.35\uff5e0.63\uff09\u30015.1\uff5e10.0 kg\u5897\u52a0\u306e\u7fa4\u3067 0.25\uff0895\uff05CI\uff1a0.15\uff5e0.42\uff09\u3001\uff1e10.0 kg\u5897\u52a0\u306e\u7fa4\u30670.33\uff0895\uff05CI\uff1a0.18\uff5e0.60\uff09\u3001\u307e\u305f\u3001\u9577\u671f\u7981\u7159\u8005\u30670.50\uff0895\uff05CI\uff1a0.46\uff5e0.55\uff09\u3067\u3042\u3063\u305f\u3002\u5168\u6b7b\u56e0\u6b7b\u4ea1\u306b\u3064\u3044\u3066\u3082\u540c\u69d8\u306e\u95a2\u9023\u304c\u8a8d\u3081\u3089\u308c\u305f\u3002<\/p>\n<p><a href=\"https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2019\/02\/201902\u8cb4\u5cf62.png\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft size-large wp-image-1625\" src=\"https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2019\/02\/201902\u8cb4\u5cf62-639x1024.png\" alt=\"201902\u8cb4\u5cf62\" width=\"639\" height=\"1024\" srcset=\"https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2019\/02\/201902\u8cb4\u5cf62-639x1024.png 639w, https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2019\/02\/201902\u8cb4\u5cf62-187x300.png 187w, https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2019\/02\/201902\u8cb4\u5cf62.png 728w\" sizes=\"auto, (max-width: 639px) 100vw, 639px\" \/><\/a><\/p>\n<p>Fig1<br \/>\n\u56f3A\uff1a2\u578b\u7cd6\u5c3f\u75c5\u306e\u30ea\u30b9\u30af\u306f\u7981\u7159\u5f8c5\u301c7\u5e74\u3067\u30d4\u30fc\u30af\u3068\u306a\u308a\u3001\u305d\u306e\u5f8c\u6e1b\u5c11\u3059\u308b\u3002<br \/>\n\u56f3B\uff1a\u4f53\u91cd\u5897\u52a0\u3092\u4f34\u308f\u306a\u3044\u6700\u8fd1\u306e\u7981\u7159\u8005\u306e2\u578b\u7cd6\u5c3f\u75c5\u306e\u30ea\u30b9\u30af\u306f\u3001\u4f53\u91cd\u304c\u5897\u52a0\u3057\u305f\u7981\u7159\u8005\u306b\u304a\u3051\u308b\u30ea\u30b9\u30af\u3088\u308a\u3082\u3001\u55ab\u7159\u3092\u3057\u305f\u3053\u3068\u304c\u306a\u3044\u4eba\u306e\u30ea\u30b9\u30af\u306b\u65e9\u304f\u8fd1\u3065\u3044\u305f\u3002<\/p>\n<p><a href=\"https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2019\/02\/201902\u8cb4\u5cf63.png\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft size-large wp-image-1626\" src=\"https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2019\/02\/201902\u8cb4\u5cf63-1024x705.png\" alt=\"201902\u8cb4\u5cf63\" width=\"640\" height=\"441\" srcset=\"https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2019\/02\/201902\u8cb4\u5cf63-1024x705.png 1024w, https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2019\/02\/201902\u8cb4\u5cf63-300x207.png 300w, https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2019\/02\/201902\u8cb4\u5cf63.png 1200w\" sizes=\"auto, (max-width: 640px) 100vw, 640px\" \/><\/a><\/p>\n<p>Fig2<br \/>\n\u56f3A\uff1a\u5fc3\u8840\u7ba1\u7cfb\u6b7b\u4ea1\u7387\u306f\u7981\u7159\u5f8c\u306b\u5927\u5e45\u306b\u6e1b\u5c11\u3057\u300110\u301c15\u5e74\u3067\u6700\u4f4e\u306b\u9054\u3057\u3001\u305d\u306e\u5f8c\u3086\u3063\u304f\u308a\u4e0a\u6607\u3057\u307e\u3057\u305f\u304c\u3001\u73fe\u5728\u306e\u55ab\u7159\u8005\u306e\u30ec\u30d9\u30eb\u306b\u306f\u5230\u9054\u3057\u306a\u304b\u3063\u305f<br \/>\n\u56f3B\uff1a\u5c64\u5225\u5206\u6790\u3067\u306f\u3001\u3053\u306e\u3088\u3046\u306a\u95a2\u9023\u30d1\u30bf\u30fc\u30f3\u304c\u3059\u3079\u3066\u306e\u4f53\u91cd\u5897\u52a0\u7fa4\u3067\u89b3\u5bdf\u3055\u308c\u305f\u304c\u3001\u4f53\u91cd\u5897\u52a0\u306a\u3057\u306e\u7fa4\u306e\u4e2d\u3067\u306f\u3001\u5fc3\u8840\u7ba1\u6b7b\u4ea1\u7387\u306f5\u301c10\u5e74\u9593\u7981\u7159\u3057\u305f\u5f8c\u6e1b\u5c11\u3057\u3001\u305d\u306e\u5f8c\u4e0a\u6607\u50be\u5411\u306a\u3057\u306b\u6a2a\u3070\u3044\u306b\u306a\u3063\u305f<br \/>\n\u56f3C\uff1a\u5168\u6b7b\u56e0\u6b7b\u4ea1\u7387\u306f5\u301c7\u5e74\u306e\u4e2d\u6b62\u3067\u5358\u8abf\u306a\u6e1b\u5c11\u3092\u793a\u3057\u3001\u305d\u306e\u5f8c\u6a2a\u3070\u3044\u72b6\u614b\u306b\u306a\u3063\u305f<br \/>\n\u56f3D\uff1a\u3053\u306e\u30d1\u30bf\u30fc\u30f3\u306f\u3001\u4f53\u91cd\u5897\u52a0\u306a\u3057\u306e\u7981\u7159\u8005\u304c\u7981\u7159\u5f8c\u306b\u76f4\u7dda\u7684\u306a\u30ea\u30b9\u30af\u6e1b\u5c11\u3092\u793a\u3057\u305f\u3053\u3068\u3092\u9664\u3044\u3066\u3001\u3059\u3079\u3066\u306e\u4f53\u91cd\u5909\u5316\u7fa4\u3067\u89b3\u5bdf\u3055\u308c\u305f<\/p>\n<p>CONCLUSIONS\uff1a<br \/>\n\u5927\u5e45\u306a\u4f53\u91cd\u5897\u52a0\u3092\u4f34\u3063\u305f\u7981\u7159\u306f\u30012\u578b\u7cd6\u5c3f\u75c5\u306e\u77ed\u671f\u7684\u306a\u30ea\u30b9\u30af\u306e\u4e0a\u6607\u306b\u95a2\u9023\u3057\u305f\u304c\u3001\u5fc3\u8840\u7ba1\u6b7b\u4ea1\u3068\u5168\u6b7b\u56e0\u6b7b\u4ea1\u306e\u6e1b\u5c11\u306b\u5bfe\u3059\u308b\u7981\u7159\u306e\u5229\u76ca\u3092\u6e1b\u5c11\u3055\u305b\u306a\u304b\u3063\u305f\u3002<\/p>\n<p>[\u958b\u50ac\u65e5]2019\u5e742\u67086\u65e5\uff08\u6c34\uff09<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u2015\u6587\u732e\u540d\u2015 Yang Hu. et al. Smoking Cessation, Weight Change, Type 2 Diabetes, and Mortality. N Engl J Med 2018; 379 &hellip; <a href=\"https:\/\/www.hcfm.jp\/journal\/?p=1623\" class=\"more-link\">\u7d9a\u304d\u3092\u8aad\u3080 <span class=\"screen-reader-text\">\u7981\u7159\u306b\u3088\u308b\u4f53\u91cd\u5897\u52a0\u306e\u5f71\u97ff<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[5,23],"tags":[],"class_list":["post-1623","post","type-post","status-publish","format-standard","hentry","category-5","category-23"],"_links":{"self":[{"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/posts\/1623","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1623"}],"version-history":[{"count":1,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/posts\/1623\/revisions"}],"predecessor-version":[{"id":1627,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/posts\/1623\/revisions\/1627"}],"wp:attachment":[{"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1623"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1623"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1623"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}