{"id":1678,"date":"2019-05-22T18:05:29","date_gmt":"2019-05-22T09:05:29","guid":{"rendered":"http:\/\/www.hcfm.jp\/journal\/?p=1678"},"modified":"2019-05-22T18:05:29","modified_gmt":"2019-05-22T09:05:29","slug":"75%e6%ad%b3%e4%bb%a5%e4%b8%8a%e3%81%ae%e9%ab%98%e9%bd%a2%e8%80%85%e3%81%ab%e5%af%be%e3%81%99%e3%82%8b%e4%b8%80%e6%ac%a1%e4%ba%88%e9%98%b2%e7%9b%ae%e7%9a%84%e3%81%a7%e3%81%ae%e3%82%b9%e3%82%bf%e3%83%81","status":"publish","type":"post","link":"https:\/\/www.hcfm.jp\/journal\/?p=1678","title":{"rendered":"75\u6b73\u4ee5\u4e0a\u306e\u9ad8\u9f62\u8005\u306b\u5bfe\u3059\u308b\u4e00\u6b21\u4e88\u9632\u76ee\u7684\u3067\u306e\u30b9\u30bf\u30c1\u30f3\u6295\u4e0e\u306e\u662f\u975e"},"content":{"rendered":"<p>\u2015\u6587\u732e\u540d\u2015<br \/>\nRafel Ramos, et al. Statins for primary prevention of cardiovascular events and mortality in old and very old adults with and without type 2 diabetes: retrospective cohort study. BMJ 2018;362:k3359.<\/p>\n<p>\u2015\u8981\u7d04\u2015<br \/>\n\u3010\u80cc\u666f\u3011<br \/>\n75\u6b73\u4ee5\u4e0a\u306e\u9ad8\u9f62\u8005\u306b\u5bfe\u3059\u308b\u5fc3\u8840\u7ba1\u75be\u60a3\uff08CVD\uff09\u3042\u308b\u3044\u306f\u5fc3\u8840\u7ba1\u6b7b\u306e\u4e8c\u6b21\u4e88\u9632\u76ee\u7684\u3067\u306e\u30b9\u30bf\u30c1\u30f3\u6295\u4e0e\u306f\u4e00\u5b9a\u78ba\u7acb\u3055\u308c\u3066\u3044\u308b\u3002\u4e00\u65b9\u3067\u300175\u6b73\u4ee5\u4e0a\u3001\u3068\u304f\u306b85\u6b73\u4ee5\u4e0a\u306e\u9ad8\u9f62\u8005\u306b\u5bfe\u3059\u308b\u4e00\u6b21\u4e88\u9632\u76ee\u7684\u3067\u306e\u30b9\u30bf\u30c1\u30f3\u6295\u4e0e\u306f\u30a8\u30d3\u30c7\u30f3\u30b9\u304c\u4e0d\u8db3\u3057\u3066\u3044\u308b\u3002<br \/>\n\u3010\u76ee\u7684\u3011<br \/>\n\u30b9\u30bf\u30c1\u30f3\u304c75\u6b73\u4ee5\u4e0a\u306e\u9ad8\u9f62\u8005\u306eCVD\u767a\u75c7\u3042\u308b\u3044\u306f\u5168\u6b7b\u4ea1\u306e\u4e00\u6b21\u4e88\u9632\u306b\u5bc4\u4e0e\u3059\u308b\u304b\u3069\u3046\u304b\u8a55\u4fa1\u3059\u308b\u3002<br \/>\n\u3010\u65b9\u6cd5\u3011<br \/>\n\u5f8c\u308d\u5411\u304d\u30b3\u30db\u30fc\u30c8\u7814\u7a76<br \/>\n\u3010\u30bb\u30c3\u30c6\u30a3\u30f3\u30b0\u3011<br \/>\n\u30b9\u30da\u30a4\u30f3\u306e\u5927\u898f\u6a21\u30c7\u30fc\u30bf\u30d9\u30fc\u30b9\u300cDatabase of the Catalan primary care system (SIDIAP)\u300d\u306e2006-15\u5e74\u5206<br \/>\n\u3010\u4e3b\u8981\u30a2\u30a6\u30c8\u30ab\u30e0\u3011<br \/>\nCVD\u767a\u75c7\u3068\u5168\u6b7b\u4ea1<br \/>\n\u3010\u7d50\u679c\u3011<br \/>\n\u81e8\u5e8a\u7684\u306bCVD\u306e\u65e2\u5f80\u304c\u306a\u304446,864\u540d\uff08\u5e73\u574777\u6b73\u300163\uff05\u306f\u5973\u6027\u3001\u8ffd\u8de1\u671f\u9593\u4e2d\u592e\u50245.6\u5e74\uff09\u304c\u767b\u9332\u3055\u308c\u305f\u3002\uff08Fig.1\uff09<br \/>\n\u7cd6\u5c3f\u75c5\u304c\u306a\u3044\u88ab\u691c\u8005\u306e\u30b9\u30bf\u30c1\u30f3\u4f7f\u7528\u306b\u3088\u308b\u30cf\u30b6\u30fc\u30c9\u6bd4\u306f\u300175-84\u6b73\u3067\u306fCVD\u767a\u75c70.94 (95%CI 0.86-1.04)\u3001\u5168\u6b7b\u4ea10.98 (0.91-1.05)\u300185\u6b73\u4ee5\u4e0a\u3067\u306fCVD\u767a\u75c70.93 (0.82-1.06)\u3001\u5168\u6b7b\u4ea1\u7387\u30000.97 (0.90-1.05)\u3060\u3063\u305f\u3002\u7cd6\u5c3f\u75c5\u304c\u3042\u308b\u88ab\u691c\u8005\u306e\u30b9\u30bf\u30c1\u30f3\u4f7f\u7528\u306b\u3088\u308b\u30cf\u30b6\u30fc\u30c9\u6bd4\u300175-84\u6b73\u3067\u306fCVD\u767a\u75c70.76 (0.65-0.89)\u3001\u5168\u6b7b\u4ea10.84 (0.75-0.94)\u300185\u6b73\u4ee5\u4e0a\u3067\u306fCVD\u767a\u75c70.82 (0.53-1.26)\u3001 \u5168\u6b7b\u4ea11.05 (0.86-1.28)\u3060\u3063\u305f\u3002\uff08Table.4\uff09<br \/>\n\u540c\u69d8\u306b\u3001\u5e74\u9f62\u306b\u3088\u308bsplines\u3092\u7528\u3044\u305f\u9023\u7d9a\u30b9\u30b1\u30fc\u30eb\u52b9\u679c\u89e3\u6790\u3067\u3001\u7cd6\u5c3f\u75c5\u306e\u306a\u304474\u6b73\u4ee5\u4e0a\u306e\u88ab\u691c\u8005\u306b\u304a\u3051\u308b\u30b9\u30bf\u30c1\u30f3\u306eCVD\u767a\u75c7\u3068\u5168\u6b7b\u4ea1\u306b\u5bfe\u3059\u308b\u5229\u76ca\u6b20\u5982\u3092\u88cf\u4ed8\u3051\u305f\u3002\u7cd6\u5c3f\u75c5\u304c\u3042\u308b\u88ab\u691c\u8005\u3067\u306f\u3001\u30b9\u30bf\u30c1\u30f3\u306eCVD\u767a\u75c7\u3068\u5168\u6b7b\u4ea1\u306b\u5bfe\u3059\u308b\u4e88\u9632\u52b9\u679c\u304c\u793a\u3055\u308c\u305f\u304c\u3001\u3053\u306e\u52b9\u679c\u306f85\u6b73\u4ee5\u4e0a\u3067\u306f\u5b9f\u8cea\u7684\u306b\u6e1b\u5c11\u3057\u300190\u6b73\u4ee5\u4e0a\u3067\u306f\u6d88\u5931\u3057\u305f\u3002\uff08Fig.2\uff09<\/p>\n<p><a href=\"https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2019\/05\/JC\uff08\u4eca\u6c5f20190522\uff09.jpg\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2019\/05\/JC\uff08\u4eca\u6c5f20190522\uff09-1024x678.jpg\" alt=\"JC\uff08\u4eca\u6c5f20190522\uff09\" width=\"640\" height=\"424\" class=\"alignleft size-large wp-image-1679\" srcset=\"https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2019\/05\/JC\uff08\u4eca\u6c5f20190522\uff09-1024x678.jpg 1024w, https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2019\/05\/JC\uff08\u4eca\u6c5f20190522\uff09-300x199.jpg 300w, https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2019\/05\/JC\uff08\u4eca\u6c5f20190522\uff09.jpg 1106w\" sizes=\"auto, (max-width: 640px) 100vw, 640px\" \/><\/a><\/p>\n<p><a href=\"https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2019\/05\/JC\uff08\u4eca\u6c5f20190522\uff091.jpg\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2019\/05\/JC\uff08\u4eca\u6c5f20190522\uff091-1024x574.jpg\" alt=\"JC\uff08\u4eca\u6c5f20190522\uff091\" width=\"640\" height=\"359\" class=\"alignleft size-large wp-image-1680\" srcset=\"https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2019\/05\/JC\uff08\u4eca\u6c5f20190522\uff091-1024x574.jpg 1024w, https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2019\/05\/JC\uff08\u4eca\u6c5f20190522\uff091-300x168.jpg 300w, https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2019\/05\/JC\uff08\u4eca\u6c5f20190522\uff091.jpg 1646w\" sizes=\"auto, (max-width: 640px) 100vw, 640px\" \/><\/a><\/p>\n<p><a href=\"https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2019\/05\/JC\uff08\u4eca\u6c5f20190522\uff092.jpg\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2019\/05\/JC\uff08\u4eca\u6c5f20190522\uff092-1024x721.jpg\" alt=\"JC\uff08\u4eca\u6c5f20190522\uff092\" width=\"640\" height=\"451\" class=\"alignleft size-large wp-image-1683\" srcset=\"https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2019\/05\/JC\uff08\u4eca\u6c5f20190522\uff092-1024x721.jpg 1024w, https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2019\/05\/JC\uff08\u4eca\u6c5f20190522\uff092-300x211.jpg 300w, https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2019\/05\/JC\uff08\u4eca\u6c5f20190522\uff092.jpg 1496w\" sizes=\"auto, (max-width: 640px) 100vw, 640px\" \/><\/a><\/p>\n<p>\u3010\u958b\u50ac\u65e5\u30112019\u5e745\u670822\u65e5\uff08\u6c34\uff09<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u2015\u6587\u732e\u540d\u2015 Rafel Ramos, et al. Statins for primary prevention of cardiovascular events and mortality in old and ver &hellip; <a href=\"https:\/\/www.hcfm.jp\/journal\/?p=1678\" class=\"more-link\">\u7d9a\u304d\u3092\u8aad\u3080 <span class=\"screen-reader-text\">75\u6b73\u4ee5\u4e0a\u306e\u9ad8\u9f62\u8005\u306b\u5bfe\u3059\u308b\u4e00\u6b21\u4e88\u9632\u76ee\u7684\u3067\u306e\u30b9\u30bf\u30c1\u30f3\u6295\u4e0e\u306e\u662f\u975e<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[5,17],"tags":[],"class_list":["post-1678","post","type-post","status-publish","format-standard","hentry","category-5","category-17"],"_links":{"self":[{"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/posts\/1678","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1678"}],"version-history":[{"count":3,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/posts\/1678\/revisions"}],"predecessor-version":[{"id":1685,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/posts\/1678\/revisions\/1685"}],"wp:attachment":[{"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1678"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1678"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1678"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}