{"id":2083,"date":"2020-12-25T10:30:44","date_gmt":"2020-12-25T01:30:44","guid":{"rendered":"http:\/\/www.hcfm.jp\/journal\/?p=2083"},"modified":"2020-12-25T10:30:44","modified_gmt":"2020-12-25T01:30:44","slug":"%e5%b0%8f%e5%85%90%e3%82%a2%e3%83%88%e3%83%94%e3%83%bc%e6%80%a7%e7%9a%ae%e8%86%9a%e7%82%8e%e3%81%ab%e3%81%8a%e3%81%91%e3%82%8b%e9%a0%bb%e7%b9%81%e3%81%aa%e5%85%a5%e6%b5%b4%e3%81%a8%e9%a0%bb%e5%ba%a6","status":"publish","type":"post","link":"https:\/\/www.hcfm.jp\/journal\/?p=2083","title":{"rendered":"\u5c0f\u5150\u30a2\u30c8\u30d4\u30fc\u6027\u76ae\u819a\u708e\u306b\u304a\u3051\u308b\u983b\u7e41\u306a\u5165\u6d74\u3068\u983b\u5ea6\u306e\u5c11\u306a\u3044\u5165\u6d74\uff1a\u7121\u4f5c\u70ba\u5316\u81e8\u5e8a\u8a66\u9a13"},"content":{"rendered":"<p>\u203b\u3053\u306e\u6642\u671f\u306eUpToDate\u306b\u3042\u308b\u201dWhat\u2019s new in family medicine\u201d\u306eTopic\u3067\u53c2\u8003\u306b\u3055\u308c\u3066\u3044\u308b\u6587\u732e\u3067\u3059\u3002<br \/>\n\uff0d\u6587\u732e\u540d\uff0d<br \/>\nCardona ID, Kempe EE, Lary C, Ginder JH, Jain N. Frequent Versus Infrequent Bathing in Pediatric Atopic Dermatitis: A Randomized Clinical Trial. J Allergy Clin Immunol Pract. 2020;8(3):1014-1021. doi:10.1016\/j.jaip.2019.10.042<\/p>\n<p>\uff0d\u8981\u7d04\uff0d<br \/>\nIntroduction\uff1a\u30a2\u30c8\u30d4\u30fc\u6027\u76ae\u819a\u708e(AD)\u306f\u6162\u6027\u306e\u76ae\u819a\u708e\u75c7\u3067\u4e16\u754c\u4e2d\u306e\u3053\u3069\u3082\u306e15~30\uff05\u306b\u5f71\u97ff\u3092\u53ca\u307c\u3057\u3066\u3044\u308b\u3002\u30a2\u30c8\u30d4\u30fc\u6027\u76ae\u819a\u708e\u306f\u76ae\u819a\u30d0\u30ea\u30a2\u6a5f\u80fd\u969c\u5bb3\u3068\u514d\u75ab\u8abf\u6574\u969c\u5bb3\u3092\u7279\u5fb4\u3068\u3059\u308b\u3002\u305d\u306e\u9ad8\u3044\u6709\u75c5\u7387\u306b\u3082\u95a2\u308f\u3089\u305a\u3001\u5c0f\u5150\u30a2\u30c8\u30d4\u30fc\u6027\u76ae\u819a\u708e\u306b\u95a2\u3059\u308b\u5165\u6d74\u983b\u5ea6\u3092\u542b\u3080\u6700\u826f\u306e\u5165\u6d74\u65b9\u6cd5\u3092\u8a55\u4fa1\u3057\u305f\u7814\u7a76\u306f\u307b\u3068\u3093\u3069\u306a\u304f\u3001\u305d\u306e\u7d50\u679c\u3001\u30a2\u30c8\u30d4\u30fc\u6027\u76ae\u819a\u708e\u306e\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u3067\u306f\u4e00\u8cab\u3057\u305f\u6839\u62e0\u306f\u306a\u3044\u72b6\u614b\u3067\u3042\u308b\u3002\u30a2\u30c8\u30d4\u30fc\u6027\u76ae\u819a\u708e\u3092\u6301\u3064\u5b50\u4f9b\u306e\u89aa\u306f\u3057\u3070\u3057\u3070\u77db\u76fe\u3059\u308b\u60c5\u5831\u3092\u53d7\u3051\u53d6\u308a\u3001\u4e0d\u6e80\u3068\u6df7\u4e71\u3092\u751f\u3093\u3067\u3044\u308b\u3002\u30d7\u30e9\u30a4\u30de\u30ea\u30b1\u30a2\u533b\u306e50%\u4ee5\u4e0b\u3057\u304b\u6bce\u65e5\u306e\u5165\u6d74\u3092\u9032\u3081\u3066\u3044\u306a\u3044\u306e\u306b\u5bfe\u3057\u3066\u3001\u5c02\u9580\u533b\uff08\u30a2\u30ec\u30eb\u30ae\u30fc\u5c02\u9580\u533b\u3001\u514d\u75ab\u5b66\u8005\u3001\u5c0f\u5150\u76ae\u819a\u79d1\u533b\uff09\u306e50%\u4ee5\u4e0a\u304c\u6bce\u65e5\u306e\u5165\u6d74\u3092\u63a8\u5968\u3057\u3066\u3044\u308b\u3068\u3044\u3046\u30c7\u30fc\u30bf\u3082\u3042\u308b\u3002<br \/>\n\u3053\u308c\u3089\u306e\u7814\u7a76\u304b\u3089PCPs\u3088\u308a\u5c02\u9580\u533b\u306f\u6bce\u65e5\u306e\u5165\u6d74\u3092\u63a8\u5968\u3059\u308b\u50be\u5411\u306b\u3042\u308a\u3001\u77db\u76fe\u3057\u305f\u30a2\u30c9\u30d0\u30a4\u30b9\u306f\u6df7\u4e71\u3068\u4e0d\u6e80\u3092\u3046\u3080\u539f\u56e0\u3068\u306a\u308a\u3046\u308b\u3002<br \/>\n\u4e2d\u7b49\u5ea6\u304b\u3089\u91cd\u75c7\u306e\u30a2\u30c8\u30d4\u30fc\u6027\u76ae\u819a\u708e\u306e\u5c0f\u5150\u306b\u5bfe\u3059\u308bwet-wrap therapy(WWT)\u306b\u3088\u308b\u9589\u9396\u7642\u6cd5\u306f\u52b9\u679c\u7684\u3067\u3042\u308b\u3068\u3055\u308c\u3066\u3044\u308b\u3002Soak and smear(or Soak and Seal)(SS)\uff1a\u5c11\u306a\u304f\u3068\u308210\u301c15\u5206\u30d0\u30b9\u30bf\u30d6\u306b\u6d78\u304b\u3063\u3066\u3001\u3059\u3050\u306b\u4e7e\u304b\u3057\u3001\u76ae\u819a\u8edf\u5316\u5264\u3067\u9589\u9396\u3092\u3059\u308b\u65b9\u6cd5\u3082\u6025\u6027\u671f\u306b\u52b9\u679c\u7684\u3067\u3042\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u308b\u3002\u30a2\u30c8\u30d4\u30fc\u6027\u76ae\u819a\u708e\u306e\u75c5\u614b\u751f\u7406\u5b66\u306b\u7f6e\u3044\u3066\u76ae\u819a\u306e\u6c34\u5206\u88dc\u7d66\u3068\u7d4c\u8868\u76ae\u6c34\u5206\u55aa\u5931\u91cf\u306e\u91cd\u8981\u6027\u3092\u8003\u616e\u3057\u3001SS\u5165\u6d74\u306f\u5c40\u6240\u85ac\u5264\u306e\u6d78\u900f\u3092\u4fc3\u9032\u3057\u3001\u6c34\u5206\u55aa\u5931\u3092\u9632\u3050\u3053\u3068\u306b\u3088\u3063\u3066WWT\u3092\u6a21\u5023\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3053\u3068\u3092\u8003\u616e\u3057\u3001\u983b\u7e41\u306aSS\u5165\u6d74\u306f\u5c0f\u5150\u306e\u30a2\u30c8\u30d4\u30fc\u6027\u76ae\u819a\u708e\u306b\u304a\u3044\u3066\u5165\u6d74\u3092\u5236\u9650\u3059\u308b\u3088\u308a\u3082\u52b9\u679c\u7684\u3067\u3042\u308b\u304b\u3082\u3057\u308c\u306a\u3044\u3068\u4eee\u5b9a\u3057\u305f\u3002<br \/>\n\u6211\u3005\u306e\u76ee\u7684\u306f\u91cd\u75c7\u306e\u30a2\u30c8\u30d4\u30fc\u6027\u76ae\u819a\u708e\u306b\u5bfe\u3057\u3066\u6025\u6027\u671f\u306e\u6cbb\u7642\u4ecb\u5165\u3068\u3057\u3066\u30011\u65e5\uff12\u56de\u300115~20\u5206\u3001SS\u5165\u6d74\u3059\u308b\u3053\u3068(Wet method : WM)\u3068\u3001\u9031\uff12\u56de\u300110\u5206\u4ee5\u4e0b\u3067SS\u5165\u6d74\u3059\u308b\u3053\u3068(dry method : DM)\u306e\u52b9\u679c\u3092\u6bd4\u8f03\u3059\u308b\u3053\u3068\u3067\u3042\u308b\u3002\u307e\u305f\u3001\u6c34\u5206\u88dc\u7d66\u72b6\u614b\u3084Staohylococcus aureus\u306e\u30b3\u30ed\u30cb\u30fc\u5f62\u6210\u3059\u308b\u5bc6\u5ea6\u3092WM\u3001DM\u9593\u3067\u5b9a\u91cf\u5316\u3057\u305f\u3002<\/p>\n<p>Method\uff1a\u3069\u306e\u3088\u3046\u306a\u65b9\u6cd5\u3092\u7528\u3044\u305f\u306e\u304b\u3001\u7279\u6b8a\u306a\u65b9\u6cd5\u3067\u3042\u308c\u3070\u9069\u5b9c\u89e3\u8aac\u3092\u5165\u308c\u308b\u3002<br \/>\n\u30a2\u30e1\u30ea\u30ab\u306e\u30e1\u30a4\u30f3\u5dde\u306e\u75c5\u9662\u95a2\u9023\u306e\u30a2\u30ec\u30eb\u30ae\u30fc\u514d\u75ab\u5b66\u8a3a\u7642\u6240\u3067\u30b7\u30f3\u30b0\u30eb\u30d6\u30e9\u30a4\u30f3\u30c9\u306e\u30af\u30ed\u30b9\u30aa\u30fc\u30d0\u30fc\u8a66\u9a13\u3092\u4f7f\u7528\u3057\u305f\u30e9\u30f3\u30c0\u30e0\u5316\u8a66\u9a13\u3092\u5b9f\u65bd\u3057\u305f\u3002\u5bfe\u8c61\u8005\u306fSCORing Atopic Dermatitis(SCORAD)index*1\u306725\u4ee5\u4e0a(\u4e2d\u7b49\u5ea6\u301c\u91cd\u5ea6)\u306e\u30a2\u30c8\u30d4\u30fc\u6027\u76ae\u819a\u708e\u306e6\u30f6\u6708\u301c11\u6b73\u306e\u5c0f\u5150\u306b\u5bfe\u3059\u308b\u3001\u983b\u7e41\u306b\u884c\u3046SS\u5165\u6d74\u3068\u983b\u7e41\u306b\u306f\u884c\u308f\u306a\u3044SS\u5165\u6d74\u306e\u983b\u5ea6\u3092\u6bd4\u8f03\u3057\u305f\u3002<br \/>\n\uff12\u30b0\u30eb\u30fc\u30d7\u306b1\uff1a1\u3067\u30e9\u30f3\u30c0\u30e0\u5316\u3057\u305f\u3002<br \/>\n\u30b0\u30eb\u30fc\u30d7\uff11\u306f\u9031\u306b\uff12\u56de\u300110\u5206\u4ee5\u4e0b\u306eSS\u5165\u6d74\u3092\uff12\u9031\u9593\u306b\u6e21\u308b\uff08DM\uff09\u5b9f\u65bd\u3057\u305f\u306e\u3061\u3001\u65e5\u306b\uff12\u56de\u300115~20\u5206\u306eSS\u5165\u6d74\u30922\u9031\u9593\u306b\u6e21\u308b\uff08WM\uff09\u5b9f\u65bd\u3057\u305f\u3002\u30b0\u30eb\u30fc\u30d7\uff12\u306f\u305d\u306e\u53cd\u5bfe\u306e\u9806\u756a\u3067\u5b9f\u65bd\u3057\u305f\u3002<br \/>\n\u60a3\u8005\u306f\u540c\u3058\u4fdd\u6e7f\u5264\u3001\u6d17\u5264\u3001\u4f4e\u30e9\u30f3\u30af\u306e\u5c40\u6240\u30b3\u30eb\u30c1\u30b3\u30b9\u30c6\u30ed\u30a4\u30c9\uff08TCS\uff09\u3092\u6295\u4e0e\u3055\u308c\u305f\u3002Primary outcome\u306fSCORing Atopic Dermatitis(SCORAD)index\u3092\u5229\u7528\u3057\u3066AD\u306e\u91cd\u75c7\u5ea6\u3092\u8a55\u4fa1\u3057\u305f\u3002<br \/>\nSecondary outcome\u306f\u30a2\u30c8\u30d4\u30fc\u6027\u76ae\u819a\u708e\u306e\u91cd\u75c7\u5ea6\uff08\u30a2\u30c8\u30d4\u30fc\u6027\u76ae\u819a\u708e\u30af\u30a4\u30c3\u30af\u30b9\u30b3\u30a2\uff08ADQ\uff09*2\u3001QOL\u3001staphylococcal aureus\u306e\u30b3\u30ed\u30cb\u30fc\u5f62\u6210\u5bc6\u5ea6\u3001\u76ae\u819a\u306e\u6c34\u5206\u88dc\u7d66\u72b6\u614b\u3001\u4fdd\u6e7f\u5264\u3001\u5c40\u6240\u30b3\u30eb\u30c1\u30b3\u30b9\u30c6\u30ed\u30a4\u30c9\u306e\u4f7f\u7528\u91cf\u306b\u95a2\u3059\u308b\u8a55\u4fa1\u3055\u308c\u305f\u3002<\/p>\n<p>Results\uff1a<br \/>\n63\u4eba\u306e\u5c0f\u5150\u3092\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u3057\u300142\u4eba\u304c\u57fa\u6e96\u3092\u6e80\u305f\u3057\u3001\u30e9\u30f3\u30c0\u30e0\u5316\u3055\u308c\u305f\u3002(Figure1)<br \/>\nAD\u306e\u91cd\u8981\u5ea6\u306b\u95a2\u3057\u3066\u3001\u4e21\u7fa4\u3067WM\u306eSCORAD\u306e\u5e73\u5747\u5909\u5316\u304c\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3\u304b\u3089\u5927\u5e45\u306b\u6e1b\u5c11\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u308f\u304b\u3063\u305f\u3002<br \/>\nWM\u3001DM\u9593\u306eSCORAD\u6cbb\u7642\u52b9\u679c\u306e\u30e2\u30c7\u30eb\u63a8\u5b9a\u5024\u306f21.2\u3060\u3063\u305f\u3002[95%CI 14.9-27.6;P&lt;.0001](table2 95%CI,14.9-27.6;P&lt;.0001).SCORAD\u306e\u81e8\u5e8a\u7684\u306b\u91cd\u8981\u306a\u5024\u306e\u5909\u5316\u306f8.7\u3067\u3042\u308a\u3001\u3053\u306e\u5909\u5316\u306f\u305d\u306e\u5dee\u3092\u8d85\u3048\u3066\u3044\u305f\u3002<br \/>\n\u3042\u308b\u7814\u7a76\u3067\u306f\u75c7\u72b6\u306e30%\u306e\u6e1b\u5c11\u304c\u81e8\u5e8a\u7684\u306b\u91cd\u8981\u3067\u3042\u308b\u3068\u898b\u306a\u3055\u308c\u3066\u304a\u308a\u3001\u30de\u30af\u30de\u30cd\u30fc\u691c\u5b9a\u3067\u4e8c\u6b21\u89e3\u6790\u3059\u308b\u3068\u3001WM\u306730%\u306e\u6539\u5584\u3092\u9054\u6210\u3057\u305f\u60a3\u8005\u306f23\u4eba\u3067\u3001DM\u3067\u306f6\u4eba\u3060\u3063\u305f\u3002WM\u306fDM\u306b\u5bfe\u3057\u3066\u5927\u5e45\u306a\u6539\u5584\u3092\u793a\u3057\u3066\u3044\u305f\uff08Figure 2: McNemar\u2019sX2=8.83,df=1,P=.0030) \u540c\u69d8\u306bWM\u306fADQ\u30925.8\u6e1b\u5c11\u3055\u305b\u3001(table\u2161 95%CI,1.8-9.7)\u7d71\u8a08\u7684\u306b\u512a\u4f4d\u306a\u6539\u5584\u3092\u793a\u3057\u305f\u3002\u3055\u3089\u306bSCORAD\u306e\u5909\u5316\u306fADQ\u306e\u5909\u5316\u3068\u76f8\u95a2\u3057\u3066\u3044\u305f\uff08\u56f3\uff13r=0.66\uff09\u3057\u304b\u3057\u3001ADQ\u306e\u89e3\u6790\u3067\u306fSCORAD\u3068\u540c\u69d8\u306e\u50be\u5411\u3092\u793a\u3057\u305f\u304c\u3001\u512a\u4f4d\u6027\u306b\u306f\u9054\u3057\u306a\u304b\u3063\u305f\u3002(P=.061)<br \/>\n\u305d\u306e\u307b\u304b\u306e\u4e8c\u6b21\u89e3\u6790\u3067\u306f\u512a\u4f4d\u306a\u5909\u5316\u306f\u8a8d\u3081\u306a\u304b\u3063\u305f<\/p>\n<p>Discussion\uff1a\u4eca\u56de\u306e\u7814\u7a76\u306e\u9650\u754c\u3001\u6b8b\u3055\u308c\u305f\u8ab2\u984c\u306a\u3069\u3092\u8a18\u8f09\u3059\u308b\u3002<br \/>\n\u4e2d\u7b49\u5ea6\u304b\u3089\u91cd\u5ea6\u306e\u30a2\u30c8\u30d4\u30fc\u6027\u76ae\u819a\u708e\u306e\u5c0f\u5150\u306b\u5bfe\u3059\u308b\u3001\u4fdd\u6e7f\u5264\u3084\u30b9\u30c6\u30ed\u30a4\u30c9\u5916\u7528\u306a\u3069\u306e\u901a\u5e38\u30b1\u30a2\u306b\u52a0\u3048\u3001\u5165\u6d74\u306e\u983b\u5ea6\u306e\u5f71\u97ff\u3092\u8abf\u3079\u3001Wet method\u306fSCORAD\u3084ADQ\u3067\u6bd4\u8f03\u3057\u305f\u5834\u5408\u306b\u7d71\u8a08\u7684\u3001\u81e8\u5e8a\u7684\u306b\u512a\u4f4d\u306b\u6539\u5584\u3092\u793a\u3059\u3053\u3068\u304c\u308f\u304b\u3063\u305f\u3002\u3053\u308c\u3089\u306e\u30c7\u30fc\u30bf\u306b\u3088\u308a1\u65e5\uff12\u5ea6\u306eSoak and seal\u5165\u6d74\u304c\u4e2d\u7b49\u5ea6\u304b\u3089\u91cd\u5ea6\u306e\u30a2\u30c8\u30d4\u30fc\u6027\u76ae\u819a\u708e\u306e\u91cd\u75c7\u5ea6\u3092\u6e1b\u3089\u3059\u3053\u3068\u304c\u793a\u3055\u308c\u305f\u3002<br \/>\n\u4eca\u56de\u306e\u7814\u7a76\u306fsingle blind \u306e\u524d\u5411\u304d\u3001\u30af\u30ed\u30b9\u30aa\u30fc\u30d0\u30fc\u30c7\u30b6\u30a4\u30f3\u306e\u30e9\u30f3\u30c0\u30e0\u5316\u8a66\u9a13\u3092\u4f7f\u3063\u305f\u3001SS\u3092\u7d44\u307f\u5408\u308f\u305b\u305f\u5165\u6d74\u983b\u5ea6\u306b\u95a2\u3059\u308b\u7591\u554f\u306b\u304a\u3051\u308b\u521d\u3081\u3066\u306e\u7814\u7a76\u3067\u3042\u308b\u3002SS\u3068\u7d44\u307f\u5408\u308f\u305b\u3066\u5165\u6d74\u983b\u5ea6\u3092\u8a55\u4fa1\u3059\u308b\u7814\u7a76\u306f\u6570\u3001\u30b5\u30a4\u30ba\u3001\u8cea\u3001\u306b\u5236\u9650\u304c\u3042\u308b\u304c\u3001\u6211\u3005\u306e\u7814\u7a76\u3067\u898b\u3089\u308c\u305fWM\u30a2\u30d7\u30ed\u30fc\u30c1\u306e\u6709\u52b9\u6027\u306f\u3053\u308c\u307e\u3067\u306e\u7814\u7a76\u3068\u4e00\u81f4\u3057\u3066\u3044\u308b\u3002<br \/>\n\u4eca\u56de\u306e\u7814\u7a76\u306e\u7d50\u679c\u306e\u8aac\u660e\u3068\u3057\u3066\u6700\u3082\u53ef\u80fd\u6027\u306e\u9ad8\u3044\u306e\u306fTCS\u306e\u5438\u53ce\u306e\u5f37\u5316\u3068\u6f5c\u5728\u7684\u306a\u30a2\u30ec\u30eb\u30b2\u30f3\u3084\u523a\u6fc0\u7269\u306e\u300c\u6d17\u3044\u6d41\u3057\u300d\u304c\u76ae\u819a\u30d0\u30ea\u30a2\u306e\u6539\u5584\u3067\u306f\u306a\u304f\u514d\u75ab\u8abf\u6574\u4e0d\u5168\u3092\u6539\u5584\u3057\u305f\u3053\u3068\u3067\u3042\u308b\u3002\u3053\u308c\u307e\u3067\u306e\u30a8\u30d3\u30c7\u30f3\u30b9\u3067\u306f\u4e7e\u71e5\u3057\u3066\u3044\u308b\u89d2\u8cea\u5c64\u3088\u308a\u6e7f\u6f64\u3057\u3066\u3044\u308b\u89d2\u8cea\u5c64\u306e\u65b9\u304c\u5c40\u6240\u85ac\u306f\u3088\u304f\u6d78\u900f\u3059\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u308b\u3002\u305d\u306e\u7d50\u679cWM\u306fwet wrap therapy\u306e\u6709\u52b9\u6027\u3092\u793a\u3055\u308c\u305f\u30e1\u30ab\u30cb\u30ba\u30e0\u3068\u540c\u69d8\u306b\u3001TCS\u306e\u6709\u52b9\u6027\u3092\u9ad8\u3081\u308b\u3053\u3068\u306b\u3088\u308a\u30b9\u30c6\u30ed\u30a4\u30c9\u3092\u7bc0\u7d04\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u308b\u304b\u3082\u3057\u308c\u306a\u3044\u3002\u307e\u305f\u3001\u76ae\u819a\u3078\u306e\u30a2\u30ec\u30eb\u30b2\u30f3\u306e\u66b4\u9732\u304c\u30a2\u30c8\u30d4\u30fc\u6027\u76ae\u819a\u708e\u306e\u708e\u75c7\u3092\u5f15\u304d\u8d77\u3053\u3057\u3066\u3044\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u3001WM\u306f\u3053\u306e\u708e\u75c7\u306e\u539f\u56e0\u3068\u306a\u308b\u9c57\u5c51\u3001\u5916\u76ae\u3001\u30a2\u30ec\u30eb\u30b2\u30f3\u3001\u523a\u6fc0\u7269\u3092\u3088\u308a\u52b9\u679c\u7684\u306b\u9664\u53bb\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3002<br \/>\n\u5c0f\u5150AD\u306e\u8868\u73fe\u578b\u306f\u6210\u4eba\u306e\u6162\u6027\u75be\u60a3\u3068\u306f\u5b9f\u8cea\u7684\u306b\u3053\u3068\u306a\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u304a\u308a\u3001\u4eca\u56de\u306f\u5c0f\u5150\u96c6\u56e3\u3092\u7814\u7a76\u3057\u3066\u304a\u308a\u3001\u6210\u4eba\u306b\u305d\u306e\u307e\u307e\u9069\u5fdc\u3059\u308b\u3053\u3068\u306f\u3067\u304d\u306a\u3044\u3002\u5c0f\u5150AD\u3067\u306fTH2\u304a\u3088\u3073TH17\/TH22\u5fdc\u7b54\u306e\u5897\u52a0\u3068TH\uff11\u6d3b\u6027\u5316\u304a\u3088\u3073INF-\u03b3\u5fdc\u7b54\u306e\u4f4e\u4e0b\u3092\u7279\u5fb4\u3068\u3059\u308b\u3002\u30a2\u30c8\u30d4\u30fc\u6027\u306e\u4f4e\u3044\u6210\u4eba\u96c6\u56e3\u3067\u3053\u308c\u3089\u306e\u7d50\u679c\u304c\u4e00\u8cab\u3057\u3066\u3044\u308b\u304b\u3069\u3046\u304b\u306f\u3063\u304d\u308a\u3057\u3066\u3044\u306a\u3044\u3002<br \/>\n\u73fe\u5b9f\u306e\u4e16\u754c\u30671\u65e5\uff12\u56de\u306eSS\u5165\u6d74\u306f\u624b\u9593\u304c\u304b\u304b\u308a\u3001\u5bb6\u65cf\u306b\u3068\u3063\u3066\u306f\u30a2\u30c9\u30d2\u30a2\u30e9\u30f3\u30b9\u304c\u96e3\u3057\u304f\u306a\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3068\u8a8d\u8b58\u3057\u3066\u3044\u308b\u3002\u6211\u3005\u306e\u7814\u7a76\u3067\u306f\u9ad8\u3044\u30a2\u30c9\u30d2\u30a2\u30e9\u30f3\u30b9\u3060\u3063\u305f\u304c\u3001\u5165\u6d74\u30ed\u30b0\u3068\u60a3\u8005\u3078\u306e\u76f4\u63a5\u306e\u96fb\u8a71\u9023\u7d61\u304c\u5fc5\u8981\u306a\u3053\u3068\u3082\u3042\u308a\u3001\u3053\u308c\u3089\u306e\u30a4\u30f3\u30bb\u30f3\u30c6\u30a3\u30d6\u306f\u7814\u7a76\u4ee5\u5916\u306e\u74b0\u5883\u3067\u306f\u5b58\u5728\u3057\u306a\u3044\u3002\u6211\u3005\u306e\u7814\u7a76\u306f\u60a3\u8005\u304c\u4e2d\u7b49\u75c7\u304b\u3089\u91cd\u75c7\u306e\u5834\u5408\u306b\u77ed\u671f\u9593\uff08\uff12\u9031\u9593\uff09\u306e\u6025\u6027\u6cbb\u7642\u4ecb\u5165\u3067\u3042\u308b\u3053\u3068\u3092\u610f\u5473\u3057\u3066\u304a\u308a\u30011\u65e5\u306b\uff12\u56de\u306e\u5165\u6d74\u306f\u5bb6\u65cf\u306b\u3088\u308a\u52b4\u529b\u3092\u5f37\u3044\u308b\u3053\u3068\u306b\u306a\u308b\u304c\u3001\u5c11\u306a\u3044\u5165\u6d74\u3088\u308a\u306f\u3088\u308a\u52b9\u679c\u7684\u3067\u3042\u308b\u3053\u3068\u3092\u793a\u3057\u305f\u3002\u307e\u305f\u3001\u4e2d\u7b49\u5ea6\u304b\u3089\u91cd\u5ea6\u7a0b\u5ea6\u306e\u5834\u5408\u306b\u30a6\u30a7\u30c3\u30c8\u30e9\u30c3\u30d7\u4e21\u65b9\u3092\u884c\u3046\u5fc5\u8981\u3084\u3088\u308a\u5f37\u529b\u306a\u5c40\u6240\u30b9\u30c6\u30ed\u30a4\u30c9\u306a\u3057\u306b\u3001\u6e7f\u75b9\u306e\u91cd\u75c7\u5ea6\u3092\u6539\u5584\u3059\u308b\u53ef\u80fd\u6027\u3092\u793a\u3057\u305f<br \/>\nAD\u306e\u6cbb\u7642\u304a\u3088\u3073\u4e88\u9632\u306b\u304a\u3051\u308bSS\u5165\u6d74\u983b\u5ea6\u306e\u5f79\u5272\u3092\u8a55\u4fa1\u3059\u308b\u306b\u306f\u3001\u3088\u308a\u5927\u898f\u6a21\u306a\u7814\u7a76\u304c\u5fc5\u8981\u3067\u3042\u308b\u3002 \u66f4\u306a\u308b\u7814\u7a76\u306b\u3088\u308a\u3001TCS\u3092\u4f7f\u7528\u3057\u306a\u3044WM\u30a2\u30d7\u30ed\u30fc\u30c1\u304c\u9577\u671f\u7684\u306bAD\u306e\u30ea\u30b9\u30af\u3092\u8efd\u6e1b\u3067\u304d\u308b\u304b\u3069\u3046\u304b\u5224\u65ad\u3055\u308c\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u304c\u3001\u4e2d\u7b49\u5ea6\u304b\u3089\u91cd\u5ea6\u306eAD\u306e6\u30f6\u6708\u301c11\u6b73\u306e\u5c0f\u5150\u3067\u306f\u3001\u6025\u6027\u671f\u6cbb\u7642\u3068\u3057\u3066WM\u30a2\u30d7\u30ed\u30fc\u30c1\u3092\u884c\u3046\u3053\u3068\u304c\u3001\u6a19\u6e96\u6cbb\u7642\u306eTCS\u3078\u306e\u4ecb\u5165\u3068\u3057\u3066\u5b89\u5168\u3067\u3042\u308a\u3001AD\u306e\u91cd\u75c7\u5ea6\u3092\u4f4e\u4e0b\u3055\u305b\u3001\u30b9\u30c6\u30ed\u30a4\u30c9\u306e\u7bc0\u7d04\u52b9\u679c\u304c\u3042\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3002<\/p>\n<p>&nbsp;<\/p>\n<p>*1&lt;\u30a2\u30c8\u30d4\u30fc\u6027\u76ae\u819a\u708e\u8a3a\u7642\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u30002018\u3088\u308a\uff1e<br \/>\n<a href=\"https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2020\/12\/JC2020\u767d\u6c34\uff11.png\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-2084\" src=\"https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2020\/12\/JC2020\u767d\u6c34\uff11.png\" alt=\"JC2020\u767d\u6c34\uff11\" width=\"591\" height=\"594\" srcset=\"https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2020\/12\/JC2020\u767d\u6c34\uff11.png 591w, https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2020\/12\/JC2020\u767d\u6c34\uff11-150x150.png 150w, https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2020\/12\/JC2020\u767d\u6c34\uff11-298x300.png 298w\" sizes=\"auto, (max-width: 591px) 100vw, 591px\" \/><\/a><\/p>\n<p>*2 ADQ<br \/>\n<a href=\"https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2020\/12\/JC2020\u767d\u6c34\uff12.png\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-2085\" src=\"https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2020\/12\/JC2020\u767d\u6c34\uff12.png\" alt=\"JC2020\u767d\u6c34\uff12\" width=\"824\" height=\"502\" srcset=\"https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2020\/12\/JC2020\u767d\u6c34\uff12.png 824w, https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2020\/12\/JC2020\u767d\u6c34\uff12-300x183.png 300w\" sizes=\"auto, (max-width: 824px) 100vw, 824px\" \/><\/a><\/p>\n<p>Carel K, Bratton DL, Miyazawa N, Gyorkos E, Kelsay K, Bender B, Strand M, Atkins D, Gelfand EW, Klinnert MD. The Atopic Dermatitis Quickscore (ADQ): validation of a new parent-administered atopic dermatitis scoring tool. Ann Allergy Asthma Immunol. 2008 Nov;101(5):500-7. doi: 10.1016\/S1081-1206(10)60289-X. PMID: 19055204.<\/p>\n<p>Figure 1<br \/>\n<a href=\"https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2020\/12\/JC2020\u767d\u6c34\uff13.png\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-2086\" src=\"https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2020\/12\/JC2020\u767d\u6c34\uff13.png\" alt=\"JC2020\u767d\u6c34\uff13\" width=\"719\" height=\"667\" srcset=\"https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2020\/12\/JC2020\u767d\u6c34\uff13.png 719w, https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2020\/12\/JC2020\u767d\u6c34\uff13-300x278.png 300w\" sizes=\"auto, (max-width: 719px) 100vw, 719px\" \/><\/a><\/p>\n<p>Table\u2161<br \/>\n<a href=\"https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2020\/12\/JC2020\u767d\u6c34\uff14.png\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-2087\" src=\"https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2020\/12\/JC2020\u767d\u6c34\uff14.png\" alt=\"JC2020\u767d\u6c34\uff14\" width=\"550\" height=\"473\" srcset=\"https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2020\/12\/JC2020\u767d\u6c34\uff14.png 550w, https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2020\/12\/JC2020\u767d\u6c34\uff14-300x258.png 300w\" sizes=\"auto, (max-width: 550px) 100vw, 550px\" \/><\/a><\/p>\n<p>Figure \uff12<br \/>\n<a href=\"https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2020\/12\/JC2020\u767d\u6c34\uff15.png\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-2088\" src=\"https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2020\/12\/JC2020\u767d\u6c34\uff15.png\" alt=\"JC2020\u767d\u6c34\uff15\" width=\"542\" height=\"529\" srcset=\"https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2020\/12\/JC2020\u767d\u6c34\uff15.png 542w, https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2020\/12\/JC2020\u767d\u6c34\uff15-300x293.png 300w\" sizes=\"auto, (max-width: 542px) 100vw, 542px\" \/><\/a><\/p>\n<p>Figure \uff13<br \/>\n<a href=\"https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2020\/12\/JC2020\u767d\u6c34\uff16.png\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-2089\" src=\"https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2020\/12\/JC2020\u767d\u6c34\uff16.png\" alt=\"JC2020\u767d\u6c34\uff16\" width=\"536\" height=\"651\" srcset=\"https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2020\/12\/JC2020\u767d\u6c34\uff16.png 536w, https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2020\/12\/JC2020\u767d\u6c34\uff16-247x300.png 247w\" sizes=\"auto, (max-width: 536px) 100vw, 536px\" \/><\/a><\/p>\n<p>\u3010\u958b\u50ac\u65e5\u30112020\u5e7412\u67089\u65e5\uff08\u6c34\uff09<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u203b\u3053\u306e\u6642\u671f\u306eUpToDate\u306b\u3042\u308b\u201dWhat\u2019s new in family medicine\u201d\u306eTopic\u3067\u53c2\u8003\u306b\u3055\u308c\u3066\u3044\u308b\u6587\u732e\u3067\u3059\u3002 \uff0d\u6587\u732e\u540d\uff0d Cardona ID, Kempe EE, Lary C, Ginde &hellip; <a href=\"https:\/\/www.hcfm.jp\/journal\/?p=2083\" class=\"more-link\">\u7d9a\u304d\u3092\u8aad\u3080 <span class=\"screen-reader-text\">\u5c0f\u5150\u30a2\u30c8\u30d4\u30fc\u6027\u76ae\u819a\u708e\u306b\u304a\u3051\u308b\u983b\u7e41\u306a\u5165\u6d74\u3068\u983b\u5ea6\u306e\u5c11\u306a\u3044\u5165\u6d74\uff1a\u7121\u4f5c\u70ba\u5316\u81e8\u5e8a\u8a66\u9a13<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[33,10],"tags":[],"class_list":["post-2083","post","type-post","status-publish","format-standard","hentry","category-whats-new","category-10"],"_links":{"self":[{"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/posts\/2083","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2083"}],"version-history":[{"count":4,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/posts\/2083\/revisions"}],"predecessor-version":[{"id":2093,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/posts\/2083\/revisions\/2093"}],"wp:attachment":[{"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2083"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=2083"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=2083"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}