{"id":2134,"date":"2021-03-31T10:49:29","date_gmt":"2021-03-31T01:49:29","guid":{"rendered":"http:\/\/www.hcfm.jp\/journal\/?p=2134"},"modified":"2021-03-31T10:49:29","modified_gmt":"2021-03-31T01:49:29","slug":"%e4%bd%8e%e7%b7%9a%e9%87%8fct%e3%81%ab%e3%82%88%e3%82%8b%e8%82%ba%e3%81%8c%e3%82%93%e6%a4%9c%e8%a8%ba%e3%81%ae%e6%9c%89%e7%9b%8a%e6%80%a7","status":"publish","type":"post","link":"https:\/\/www.hcfm.jp\/journal\/?p=2134","title":{"rendered":"\u4f4e\u7dda\u91cfCT\u306b\u3088\u308b\u80ba\u304c\u3093\u691c\u8a3a\u306e\u6709\u76ca\u6027"},"content":{"rendered":"

\uff0d\u6587\u732e\u540d\uff0d
\nMark H. Ebell, Michelle Bentivegna and Cassie Hulme. Cancer-Specific Mortality, All-Cause Mortality, and Overdiagnosis in Lung Cancer Screening Trials: A Meta-Analysis. The Annals of Family Medicine November 2020, 18 (6) 545-552.<\/p>\n

\uff0d\u8981\u7d04\uff0d
\n\u3010\u80cc\u666f\u3011\u80ba\u304c\u3093\u306f\u7f79\u60a3\u7387\u3068\u6b7b\u4ea1\u7387\u306e\u91cd\u8981\u306a\u539f\u56e0\u3067\u3042\u308a\u30012020\u5e74\u306b\u306f\u63a8\u5b9a228,820\u4eba\u304c\u65b0\u305f\u306b\u8a3a\u65ad\u3055\u308c\u3001135,720\u4eba\u304c\u6b7b\u4ea1\u3059\u308b\u3068\u4e88\u60f3\u3055\u308c\u3066\u3044\u308b\u3002\u65e9\u671f\u767a\u898b\u306f\u4e73\u304c\u3093\u3068\u5927\u8178\u304c\u3093\u306e\u75be\u60a3\u7279\u7570\u7684\u6b7b\u4ea1\u7387\u3092\u6e1b\u5c11\u3055\u305b\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u308b\u3002\u80f8\u90e8X\u7dda\u64ae\u5f71\u306b\u3088\u308b\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u306f\u80ba\u304c\u3093\u8a3a\u65ad\u6642\u304b\u3089\u306e\u751f\u5b58\u7387\u3092\u6539\u5584\u3059\u308b\u304c\u3001\u3053\u306e\u52b9\u679c\u306f\u30ea\u30fc\u30c9\u30bf\u30a4\u30e0\u30d0\u30a4\u30a2\u30b9\u306b\u3088\u308b\u3082\u306e\u3067\u3042\u308a\u3001\u80ba\u304c\u3093\u7279\u7570\u7684\u6b7b\u4ea1\u7387\u3068\u5168\u6b7b\u4ea1\u7387\u306f\u6539\u5584\u3055\u308c\u3066\u3044\u306a\u3044\u3002National Lung Screening Trial\uff08NLST\uff09\u3067\u306f\u300155\uff5e74\u6b73\u3067\u5c11\u306a\u304f\u3068\u308230\u5e74\u4ee5\u4e0a\u306e\u55ab\u7159\u6b74\u304c\u3042\u308a\u3001\u73fe\u5728\u55ab\u7159\u8005\u3067\u3042\u308b\u304b\u3001\u307e\u305f\u306f\u904e\u53bb15\u5e74\u4ee5\u5185\u306b\u7981\u7159\u3057\u305f\u3053\u3068\u304c\u3042\u308b53,454\u4eba\u306e\u53c2\u52a0\u8005\u3092\u5bfe\u8c61\u306b\u3001\u4f4e\u7dda\u91cf\u30b3\u30f3\u30d4\u30e5\u30fc\u30bf\u65ad\u5c64\u64ae\u5f71\uff08LDCT\uff09\u3068\u80f8\u90e8X\u7dda\u64ae\u5f71\u3092\u6bd4\u8f03\u3057\u305f\u3002 NLST\u306e\u7d50\u679c\u306f2011\u5e74\u306b\u767a\u8868\u3055\u308c\u30012013\u5e74\u306b\u306f\u7c73\u56fd\u4e88\u9632\u30b5\u30fc\u30d3\u30b9\u30bf\u30b9\u30af\u30d5\u30a9\u30fc\u30b9\u304c\u3001\u73fe\u5728\u306e\u55ab\u7159\u8005\u307e\u305f\u306f\u904e\u53bb15\u5e74\u9593\u306b\u7981\u7159\u3057\u305f\u55ab\u7159\u6b7430\u5e74\u306e55\uff5e80\u6b73\u306e\u4eba\u306bLDCT\u3092\u7528\u3044\u305f\u80ba\u304c\u3093\u691c\u8a3a\u3092\u63a8\u5968\u3057\u305f\u3002 \u30a4\u30bf\u30ea\u30a2\u306eDetection and Screening of Early Lung Cancer With Novel Imaging Technology\uff08DANTE\uff09\u8a66\u9a13\u3067\u306f1.01\uff0895\uff05CI\u30010.70-1.44\uff09\u3001\u30c7\u30f3\u30de\u30fc\u30af\u306e\u80ba\u304c\u3093\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u8a66\u9a13\uff08DLCST\uff09\u3067\u306f1.03\uff0895\uff05CI\u30010.66-1.60\uff09\u3067\u3042\u3063\u305f.2019\u5e74\u306e\u30e1\u30bf\u30a2\u30ca\u30ea\u30b7\u30b9\u3067\u306f\u3001\u6b7b\u4ea1\u7387\u306e\u7d50\u679c\u304c\u5f97\u3089\u308c\u305f5\u4ef6\u306e\u7814\u7a76\u306e\u307f\u304c\u540c\u5b9a\u3055\u308c\u305f\u3002 \u540c\u5e74\u306e\u7b2c2\u56de\u30e1\u30bf\u30a2\u30ca\u30ea\u30b7\u30b9\u3067\u306f\u3001LDCT\u3092\u7528\u3044\u305f\u80ba\u304c\u3093\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u306e\u30e9\u30f3\u30c0\u30e0\u5316\u8a66\u9a139\u4ef6\u306e\u6b7b\u4ea1\u7387\u30c7\u30fc\u30bf\u304c\u5831\u544a\u3055\u308c\u305f\u304c\u3001\u30aa\u30e9\u30f3\u30c0\u3068\u30d9\u30eb\u30ae\u30fc\u306e\u8a66\u9a13\u3067\u3042\u308bNederlands-Leuvens Longkanker Screenings Onderzoek\uff08NELSON\uff09\u8a66\u9a13\u306e\u6700\u7d42\u30c7\u30fc\u30bf\u306f\u30012020\u5e742\u6708\u307e\u3067\u516c\u8868\u3055\u308c\u3066\u304a\u3089\u305a\u3001\u542b\u307e\u308c\u3066\u3044\u306a\u304b\u3063\u305f\u3002\u3055\u3089\u306b\u3001\u3053\u306e\u30e1\u30bf\u30a2\u30ca\u30ea\u30b7\u30b9\u3067\u306f\u3001\u6b20\u9665\u306e\u3042\u308b\u8a66\u9a13\u306e\u30c7\u30fc\u30bf\u304c\u542b\u307e\u308c\u3066\u304a\u308a\u3001\u5168\u6b7b\u56e0\u6b7b\u4ea1\u7387\u306e\u30c7\u30fc\u30bf\u3068NELSON\u8a66\u9a13\u306e\u5973\u6027\u306e\u30c7\u30fc\u30bf\u304c\u9664\u5916\u3055\u308c\u3066\u304a\u308a\u3001\u7d76\u5bfe\u7684\u306a\u30ea\u30b9\u30af\u4f4e\u4e0b\u3068\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u306b\u5fc5\u8981\u306a\u6570\u304c\u63a8\u5b9a\u3055\u308c\u3066\u3044\u306a\u304b\u3063\u305f\u3002\u305d\u3053\u3067\u6211\u3005\u306f\u3001\u80ba\u304c\u3093\u306b\u5bfe\u3059\u308bLDCT\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u3068\u75be\u60a3\u7279\u7570\u7684\u6b7b\u4ea1\u7387\u304a\u3088\u3073\u5168\u6b7b\u56e0\u6b7b\u4ea1\u7387\u3068\u306e\u95a2\u4fc2\u3092\u7406\u89e3\u3059\u308b\u3053\u3068\u3092\u76ee\u7684\u3068\u3057\u3066\u3001\u3053\u308c\u3089\u306e\u5236\u9650\u306b\u5bfe\u51e6\u3057\u305f\u8cea\u306e\u9ad8\u3044\u30e9\u30f3\u30c0\u30e0\u5316\u6bd4\u8f03\u8a66\u9a13\u306e\u30e1\u30bf\u30a2\u30ca\u30ea\u30b7\u30b9\u3092\u65b0\u305f\u306b\u5b9f\u65bd\u3057\u305f\u3002\u7b2c\u4e8c\u306b\u3001\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u306e\u91cd\u8981\u306a\u6f5c\u5728\u7684\u5371\u5bb3\u3067\u3042\u308b\u904e\u5270\u8a3a\u65ad\u306e\u8a3c\u62e0\u3092\u8a55\u4fa1\u3057\u305f\u3002
\n\u3010\u76ee\u7684\u3011\u80ba\u304c\u3093\u7279\u7570\u7684\u6b7b\u4ea1\u7387\u304a\u3088\u3073\u5168\u6b7b\u4ea1\u7387\u3092\u6e1b\u5c11\u3055\u305b\u308b\u305f\u3081\u306e\u4f4e\u7dda\u91cf\u30b3\u30f3\u30d4\u30e5\u30fc\u30bf\u65ad\u5c64\u64ae\u5f71\uff08LDCT\uff09\u3092\u7528\u3044\u305f\u80ba\u304c\u3093\u691c\u8a3a\u306e\u6709\u76ca\u6027\u306f\u660e\u3089\u304b\u3067\u306f\u306a\u3044\u3002\u6211\u3005\u306f\u3001\u8ee2\u5e30\u3068\u306e\u95a2\u9023\u3092\u8a55\u4fa1\u3059\u308b\u305f\u3081\u306b\u30e1\u30bf\u30a2\u30ca\u30ea\u30b7\u30b9\u3092\u5b9f\u65bd\u3057\u305f\u3002
\n\u3010\u65b9\u6cd5\u3011LDCT\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u3068\u901a\u5e38\u306e\u30b1\u30a2\u307e\u305f\u306f\u80f8\u90e8X\u7dda\u64ae\u5f71\u3092\u6bd4\u8f03\u3059\u308b\u30e9\u30f3\u30c0\u30e0\u5316\u6bd4\u8f03\u8a66\u9a13\u3092\u540c\u5b9a\u3059\u308b\u305f\u3081\u306b\u3001\u6587\u732e\u304a\u3088\u3073\u4ee5\u524d\u306e\u30b7\u30b9\u30c6\u30de\u30c6\u30a3\u30c3\u30af\u30ec\u30d3\u30e5\u30fc\u3092\u691c\u7d22\u3057\u305f\u3002\u30e9\u30f3\u30c0\u30e0\u52b9\u679c\u30e2\u30c7\u30eb\u3092\u7528\u3044\u3066\u30e1\u30bf\u30a2\u30ca\u30ea\u30b7\u30b9\u3092\u884c\u3063\u305f\u3002\u4e3b\u8981\u30a2\u30a6\u30c8\u30ab\u30e0\u306f\u3001\u80ba\u304c\u3093\u7279\u7570\u7684\u6b7b\u4ea1\u7387\u3001\u5168\u6b7b\u56e0\u6b7b\u4ea1\u7387\u3001\u304a\u3088\u3073\u904e\u5270\u8a3a\u65ad\u306e\u6307\u6a19\u3068\u3057\u3066\u306e\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u7fa4\u3068\u975e\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u7fa4\u306e\u9593\u306e\u80ba\u304c\u3093\u306e\u7d2f\u7a4d\u767a\u751f\u7387\u3067\u3042\u3063\u305f\u3002
\n\u3010\u7d50\u679c\u3011\u30d0\u30a4\u30a2\u30b9\u306e\u30ea\u30b9\u30af\u304c\u4f4e\u304490,475\u4eba\u306e\u60a3\u8005\u3092\u5bfe\u8c61\u3068\u3057\u305f8\u3064\u306e\u8a66\u9a13\u306b\u57fa\u3065\u3044\u3066\u30e1\u30bf\u30a2\u30ca\u30ea\u30b7\u30b9\u3092\u884c\u3063\u305f\u3002LDCT\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u306b\u3088\u308a\u80ba\u304c\u3093\u7279\u7570\u7684\u6b7b\u4ea1\u7387\u306e\u6709\u610f\u306a\u6e1b\u5c11\u304c\u8a8d\u3081\u3089\u308c\u305f\uff08\u76f8\u5bfe\u30ea\u30b9\u30af\uff1d0.81\uff1b95\uff05CI\u30010.74-0.89\uff09(Figure.2)\uff1b\u63a8\u5b9a\u7d76\u5bfe\u30ea\u30b9\u30af\u306e\u6e1b\u5c11\u306f0.4\uff05\uff08\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u306b\u5fc5\u8981\u306a\u6570\uff1d250\uff09\u3067\u3042\u3063\u305f\u3002\u5168\u6b7b\u56e0\u6b7b\u4ea1\u7387\u306e\u6e1b\u5c11\u306f\u7d71\u8a08\u7684\u306b\u6709\u610f\u3067\u306f\u306a\u304b\u3063\u305f\uff08\u76f8\u5bfe\u30ea\u30b9\u30af\uff1d0.96\uff1b95\uff05CI\u30010.92-1.01\uff09(Figure.3)\u304c\u3001\u7d76\u5bfe\u30ea\u30b9\u30af\u306e\u6e1b\u5c11\u306f\u80ba\u304c\u3093\u7279\u7570\u7684\u6b7b\u4ea1\u7387\u306e\u6e1b\u5c11\u3068\u4e00\u81f4\u3057\u3066\u3044\u305f\uff080.34\uff05\uff1b\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u306b\u5fc5\u8981\u306a\u6570\uff1d294\uff09\u3002\u8ffd\u8de1\u671f\u9593\u304c\u6700\u3082\u9577\u3044\u7814\u7a76\u3067\u306f\u3001\u80ba\u304c\u3093\u306e\u767a\u751f\u7387\u306f\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u7fa4\u306725\uff05\u9ad8\u304f\u3001\u904e\u5270\u8a3a\u65ad\u306e\u5272\u5408\u306f20\uff05\u3067\u3042\u3063\u305f\u3002
\n\u3010\u7d50\u8ad6\u3011\u3053\u306e\u30e1\u30bf\u30a2\u30ca\u30ea\u30b7\u30b9\u306f\u3001\u904e\u5270\u8a3a\u65ad\u306e\u53ef\u80fd\u6027\u306e\u30c8\u30ec\u30fc\u30c9\u30aa\u30d5\u306f\u3042\u308b\u3082\u306e\u306e\u3001\u80ba\u304c\u3093\u7279\u7570\u7684\u6b7b\u4ea1\u7387\u306e\u6709\u610f\u306a\u6e1b\u5c11\u3092\u793a\u3057\u3066\u304a\u308a\u3001\u80ba\u304c\u3093\u30ea\u30b9\u30af\u306e\u9ad8\u3044\u4eba\u306b\u306fLDCT\u306b\u3088\u308b\u80ba\u304c\u3093\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u3092\u63a8\u5968\u3059\u308b\u3053\u3068\u3092\u652f\u6301\u3057\u3066\u3044\u308b\u3002<\/p>\n

\"\"<\/p>\n

\"\"<\/p>\n

\"\"<\/p>\n

\u3010\u958b\u50ac\u65e5\u30112021\u5e743\u67083\u65e5\uff08\u6c34\uff09<\/p>\n","protected":false},"excerpt":{"rendered":"

\uff0d\u6587\u732e\u540d\uff0d Mark H. Ebell, Michelle Bentivegna and Cassie Hulme. Cancer-Specific Mortality, All-Cause Mortality, and … \u7d9a\u304d\u3092\u8aad\u3080 \u4f4e\u7dda\u91cfCT\u306b\u3088\u308b\u80ba\u304c\u3093\u691c\u8a3a\u306e\u6709\u76ca\u6027<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[5],"tags":[],"class_list":["post-2134","post","type-post","status-publish","format-standard","hentry","category-5"],"_links":{"self":[{"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/posts\/2134","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2134"}],"version-history":[{"count":1,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/posts\/2134\/revisions"}],"predecessor-version":[{"id":2138,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/posts\/2134\/revisions\/2138"}],"wp:attachment":[{"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2134"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=2134"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=2134"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}