{"id":2173,"date":"2021-07-20T11:08:06","date_gmt":"2021-07-20T02:08:06","guid":{"rendered":"https:\/\/www.hcfm.jp\/journal\/?p=2173"},"modified":"2021-07-20T11:08:06","modified_gmt":"2021-07-20T02:08:06","slug":"%e7%89%b9%e7%99%ba%e6%80%a7%e8%82%ba%e7%b7%9a%e7%b6%ad%e7%97%87%e3%81%ae%e6%97%a9%e6%9c%9f%e8%a8%ba%e6%96%ad%e3%81%ab%e3%81%8a%e3%81%91%e3%82%8bfine-crackles","status":"publish","type":"post","link":"https:\/\/www.hcfm.jp\/journal\/?p=2173","title":{"rendered":"\u7279\u767a\u6027\u80ba\u7dda\u7dad\u75c7\u306e\u65e9\u671f\u8a3a\u65ad\u306b\u304a\u3051\u308bfine crackles"},"content":{"rendered":"

\u2015\u6587\u732e\u540d\u2015
\nOnofre Moran-Mendoza, Thomas Ritchie, Sharina Aldhaheri. Fine crackles on chest auscultation in the early diagnosis of idiopathic pulmonary fibrosis: a prospective cohort study. BMJ Open Resp Res: first published as 10.1136\/bmjresp-2020-000815 on 7 July 2021.<\/p>\n

\u2015\u8981\u7d04\u2015
\nIntroduction\uff1a<\/strong>
\n\u7279\u767a\u6027\u80ba\u7dda\u7dad\u75c7\uff08IPF\uff09\u306f\u3001\u539f\u56e0\u4e0d\u660e\u306e\u9593\u8cea\u6027\u80ba\u75be\u60a3\uff08ILD\uff09\u3067\u3042\u308a\u3001\u901a\u5e3860\u6b73\u4ee5\u4e0a\u3067\u767a\u75c7\u3057\u3001\u4e88\u5f8c\u306f\u4e0d\u826f\u3067\u3001\u8a3a\u65ad\u6642\u304b\u3089\u306e\u751f\u5b58\u671f\u9593\u306e\u4e2d\u592e\u5024\u306f2\uff5e3\u5e74\u3067\u3042\u308b\u3002IPF\u306f\u3001\u539f\u56e0\u4e0d\u660e\u306e\u547c\u5438\u56f0\u96e3\u3092\u4f34\u3046\u3059\u3079\u3066\u306e\u6210\u4eba\u60a3\u8005\u3067\u8003\u616e\u3055\u308c\u308b\u3079\u304d\u3067\u3042\u308a\u3001\u4e00\u822c\u306b\u54b3\u3001\u4e8c\u57fa\u5e95\u6027\u5438\u6c17\u6027\u30e9\u97f3\u3001\u3070\u3061\u6307\u3092\u5448\u3059\u308b\u3002IPF\u306e\u8a3a\u65ad\u3068\u6cbb\u7642\u306e\u958b\u59cb\u306f2\u5e74\u4ee5\u4e0a\u9045\u308c\u308b\u3053\u3068\u304c\u3042\u308a\u3001\u305d\u306e\u7d50\u679c\u6b7b\u4ea1\u7387\u304c\u9ad8\u304f\u306a\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u308b\u3002\u73fe\u5728\u3001\u30cb\u30f3\u30c6\u30c0\u30cb\u30d6\u3068\u30d4\u30eb\u30d5\u30a7\u30cb\u30c9\u30f3\u306e2\u3064\u306e\u5229\u7528\u53ef\u80fd\u306a\u6297\u7dda\u7dad\u5316\u85ac\u304c\u3042\u308a\u3001\u3053\u308c\u3089\u306f\u75c5\u6c17\u306e\u9032\u884c\u3092\u9045\u3089\u305b\u3001\u6b7b\u4ea1\u7387\u3092\u4f4e\u4e0b\u3055\u305b\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3002IPF\u304c\u7591\u308f\u308c\u308b\u60a3\u8005\u3092\u5c02\u9580\u533b\u306b\u65e9\u671f\u306b\u7d39\u4ecb\u3059\u308b\u3053\u3068\u3067\u3001\u65e9\u671f\u306e\u6cbb\u7642\u3068\u4e88\u5f8c\u306e\u6539\u5584\u306b\u7e4b\u304c\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3002
\n\u9ad8\u89e3\u50cf\u5ea6\u80f8\u90e8CT\u306f\u3001ILD\u3092\u8a3a\u65ad\u3059\u308b\u305f\u3081\u306e\u6700\u826f\u306e\u975e\u4fb5\u8972\u7684\u691c\u67fb\u3060\u304c\u3001\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u3068\u3057\u3066\u4f7f\u7528\u3059\u308b\u306b\u306f\u8cbb\u7528\u304c\u304b\u304b\u308a\u3001\u5b9f\u7528\u7684\u3067\u306f\u306a\u3044\u3002\u80f8\u90e8\u8074\u8a3a\u306b\u3088\u308bfine crackles\u306f\u3001\u73fe\u5728\u3001IPF\u3092\u65e9\u671f\u306b\u8a3a\u65ad\u3059\u308b\u305f\u3081\u306e\u552f\u4e00\u306e\u73fe\u5b9f\u7684\u306a\u624b\u6bb5\u3067\u3042\u308b\u3053\u3068\u304c\u793a\u5506\u3055\u308c\u3066\u3044\u308b\u3002\u3053\u308c\u307e\u3067\u3001IPF\u306e\u65e9\u671f\u8a3a\u65ad\u306b\u304a\u3051\u308bfine crackles\u306e\u5f79\u5272\u3092\u8a55\u4fa1\u3057\u305f\u7814\u7a76\u306f\u306a\u3044\u3002
\n\u4eca\u56de\u3001IPF\u304a\u3088\u3073\u4ed6\u306eILD\u306e\u65e9\u671f\u8a3a\u65ad\u306b\u304a\u3051\u308bfine crackles\u306e\u6709\u7528\u6027\u3092\u8a55\u4fa1\u3059\u308b\u76ee\u7684\u3067\u7814\u7a76\u3092\u884c\u3063\u305f\u3002<\/p>\n

Method\uff1a<\/strong>
\n\u30ab\u30ca\u30c0\u306e\u30aa\u30f3\u30bf\u30ea\u30aa\u5dde\u306b\u3042\u308b\u30ad\u30f3\u30b0\u30b9\u30c8\u30f3\u5065\u5eb7\u79d1\u5b66\u30bb\u30f3\u30bf\u30fc\u306eILD\u30af\u30ea\u30cb\u30c3\u30af\u306b\u7d39\u4ecb\u3055\u308c\u305f\u3059\u3079\u3066\u306e\u60a3\u8005\u306e\u80f8\u90e8\u8074\u8a3a\u306b\u304a\u3051\u308b\u30af\u30e9\u30c3\u30af\u30eb\u97f3\u306e\u5b58\u5728\u3068\u7a2e\u985e\u3092\u524d\u5411\u304d\u306b\u8a55\u4fa1\u3057\u305f\u3002\u3053\u306e\u7814\u7a76\u306b\u542b\u307e\u308c\u308b\u60a3\u8005\u306f\u3001IPF\u306e\u4e8b\u524d\u8a3a\u65ad\u304c\u306a\u304f\u3001\u4e00\u90e8\u306e\u60a3\u8005\u306f\u7121\u75c7\u5019\u6027\u3067\u3042\u308b\u304b\u3001\u547c\u5438\u6a5f\u80fd\u691c\u67fb\u3067\u6b63\u5e38\u3068\u3055\u308c\u3066\u3044\u305f\u3002ILD\u306e\u6700\u7d42\u8a3a\u65ad\u304c\u78ba\u7acb\u3055\u308c\u308b\u524d\u306b\u3001\u69d8\u3005\u306a\u30ec\u30d9\u30eb\u306e\u7d4c\u9a13\u3092\u6301\u3064\u81e8\u5e8a\u533b\u304c\u80f8\u90e8\u8074\u8a3a\u3092\u884c\u3044\u3001\u4ed6\u306e\u81e8\u5e8a\u533b\u306e\u8a55\u4fa1\u3068\u6700\u7d42\u8a3a\u65ad\u3092\u77e5\u3089\u3055\u308c\u3066\u3044\u306a\u3044\u6a19\u6e96\u5316\u3055\u308c\u305f\u30c7\u30fc\u30bf\u53ce\u96c6\u30d5\u30a9\u30fc\u30e0\u306bcrackles\u306e\u5b58\u5728\u3068\u7a2e\u985e\u3092\u8a18\u9332\u3057\u305f\u3002
\nCrackles\u306e\u5b58\u5728\u3068\u7a2e\u985e\u306f\u3001\u5404\u60a3\u8005\u306e\u6700\u521d\u3068\u305d\u306e\u5f8c\u306e\u6765\u9662\u6642\u306b\u3001\u81e8\u5e8a\u533b\u306b\u3088\u3063\u3066\u6b21\u306e\u3088\u3046\u306b\u8a18\u9332\u3055\u308c\u305f\uff1a(a) no crackles, (b) fine crackles, (c) coarse crackles, (d) fine crackles\u3068coarse crackles\u306e\u4e21\u65b9\u3002crackles\u306e\u8b58\u5225\u306f\u3001\u8a3a\u65ad\uff08IPF\u3068\u975eIPF\uff09\u3001\u304a\u3088\u3073crackles\u306e\u8b58\u5225\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u53ef\u80fd\u6027\u306e\u3042\u308b\u60a3\u8005\u3068\u81e8\u5e8a\u533b\u306e\u7279\u6027\u306b\u3088\u3063\u3066\u5c64\u5225\u5316\u3055\u308c\u305f\u3002<\/p>\n

Results\uff1a<\/strong>
\nILD\u30af\u30ea\u30cb\u30c3\u30af\u306b\u7d39\u4ecb\u3055\u308c\u305f290\u540d\u306eILD\u60a3\u8005\u3092\u8a55\u4fa1\u3057\u305f\u3002\u6700\u521d\u306e\u6240\u898b\u3067\u306f\u3001IPF\u60a3\u8005\u306e93%\u3068\u975eIPF\u306eILD\u60a3\u8005\u306e73%\u304c\u8074\u8a3a\u3067fine crackles\u3092\u8a8d\u3081\u305f\u3002IPF\u306e\u60a3\u8005\u3067\u306f\u3001\u54b3\uff0886\uff05\uff09\u3001\u547c\u5438\u56f0\u96e3\uff0880\uff05\uff09\u3001\u62e1\u6563\u80fd\u306e\u4f4e\u4e0b\uff0887\uff05\uff09\u3001\u7dcf\u80ba\u6d3b\u91cf\u306e\u4f4e\u4e0b\uff0857\uff05\uff09\u3001\u5f37\u5236\u80ba\u6d3b\u91cf\u306e\u4f4e\u4e0b\uff0850\uff05\uff09\u3088\u308a\u3082fine crackles\u304c\u4e00\u822c\u7684\u3060\u3063\u305f\u3002\u305d\u306e\u5f8c\u306e\u6765\u9662\u6642\u306e\u8a3a\u5bdf\u3067\u306f\u3001\u6700\u521d\u306bfine crackles\u3092\u8a8d\u3081\u305f\u60a3\u8005\u306e90\uff05\u3067\u3001\u540c\u3058\u30bf\u30a4\u30d7\u306ecrackle\u97f3\u304c\u78ba\u8a8d\u3055\u308c\u305f\u3002\u91cd\u56de\u5e30\u5206\u6790\u3067\u306f\u3001fine crackles\u306e\u8b58\u5225\u306f\u3001\u80ba\u6a5f\u80fd\u3001\u75c7\u72b6\u3001\u80ba\u6c17\u816b\u3001COPD\u3001\u80a5\u6e80\u3001\u307e\u305f\u306f\u81e8\u5e8a\u533b\u306e\u7d4c\u9a13\u306b\u3088\u308b\u5f71\u97ff\u3092\u53d7\u3051\u306a\u304b\u3063\u305f\u3002<\/p>\n

Discussion\uff1a<\/strong>
\n\u672c\u7814\u7a76\u306e\u7d50\u679c\u3001\u7121\u75c7\u5019\u6027\u306e\u60a3\u8005\u3084\u547c\u5438\u6a5f\u80fd\u691c\u67fb\u3067\u6b63\u5e38\u3060\u3063\u305f\u60a3\u8005\u3092\u542b\u3080\u3001\u307b\u3068\u3093\u3069\u306eIPF\u60a3\u8005\u306bfine crackles\u304c\u5b58\u5728\u3057\u3001\u80ba\u6c17\u816b\u3001COPD\u3001\u80a5\u6e80\u306e\u60a3\u8005\u3001\u307e\u305f\u306f\u80f8\u90e8\u8074\u8a3a\u3092\u884c\u3063\u305f\u81e8\u5e8a\u533b\u306e\u7d4c\u9a13\u306b\u95a2\u4fc2\u306a\u304f\u3001\u9069\u5207\u306b\u8b58\u5225\u3067\u304d\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u305f\u3002\u80f8\u90e8\u8074\u8a3a\u306efine crackles\u306f\u3001IPF\u3084\u4ed6\u306eILD\u60a3\u8005\u306e\u65e9\u671f\u8a3a\u65ad\u3068\u6cbb\u7642\u306b\u7e4b\u304c\u308b\u53ef\u80fd\u6027\u306e\u3042\u308b\u3001\u9ad8\u611f\u5ea6\u3067\u5805\u7262\u306a\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u30c4\u30fc\u30eb\u3067\u3042\u308b\u3002<\/p>\n

\u3010\u958b\u50ac\u65e5\u3011
\n2021\u5e747\u670814\u65e5\uff08\u6c34\uff09<\/p>\n","protected":false},"excerpt":{"rendered":"

\u2015\u6587\u732e\u540d\u2015 Onofre Moran-Mendoza, Thomas Ritchie, Sharina Aldhaheri. Fine crackles on chest auscultation in the earl … \u7d9a\u304d\u3092\u8aad\u3080 \u7279\u767a\u6027\u80ba\u7dda\u7dad\u75c7\u306e\u65e9\u671f\u8a3a\u65ad\u306b\u304a\u3051\u308bfine crackles<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[23,17],"tags":[],"class_list":["post-2173","post","type-post","status-publish","format-standard","hentry","category-23","category-17"],"_links":{"self":[{"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/posts\/2173","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2173"}],"version-history":[{"count":1,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/posts\/2173\/revisions"}],"predecessor-version":[{"id":2174,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/posts\/2173\/revisions\/2174"}],"wp:attachment":[{"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2173"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=2173"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=2173"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}