{"id":2266,"date":"2023-03-23T11:07:56","date_gmt":"2023-03-23T02:07:56","guid":{"rendered":"https:\/\/www.hcfm.jp\/journal\/?p=2266"},"modified":"2023-03-23T11:07:56","modified_gmt":"2023-03-23T02:07:56","slug":"%e5%a4%89%e5%bd%a2%e6%80%a7%e8%86%9d%e3%83%bb%e8%82%a1%e9%96%a2%e7%af%80%e7%97%87%e3%81%b8%e3%81%aensaids%e3%80%81%e3%82%aa%e3%83%94%e3%82%aa%e3%82%a4%e3%83%89%e6%b2%bb%e7%99%82%e3%81%ae%e6%9c%89","status":"publish","type":"post","link":"https:\/\/www.hcfm.jp\/journal\/?p=2266","title":{"rendered":"\u5909\u5f62\u6027\u819d\u30fb\u80a1\u95a2\u7bc0\u75c7\u3078\u306eNSAIDs\u3001\u30aa\u30d4\u30aa\u30a4\u30c9\u6cbb\u7642\u306e\u6709\u52b9\u6027\u3068\u5b89\u5168\u6027"},"content":{"rendered":"<p>\u2015\u6587\u732e\u540d\u2015<br \/>\nBruno R da Costa. Effectiveness and safety of non-steroidal anti-inflammatory drugs and opioid treatment for knee and hip osteoarthritis: network meta-analysis. BMJ 2021;375:n2321: published 12 October 2021.<\/p>\n<p>\u2015\u8981\u7d04\u2015<br \/>\nIntroduction\uff1a<br \/>\n\u3000\u5909\u5f62\u6027\u95a2\u7bc0\u75c7\u306f\u75db\u307f\u306b\u3088\u308a\u3001\u8eab\u4f53\u6a5f\u80fd\u3068QOL\u304c\u4f4e\u4e0b\u3057\u3001\u5168\u3066\u306e\u539f\u56e0\u306b\u3088\u308b\u6b7b\u4ea1\u30ea\u30b9\u30af\u304c\u9ad8\u307e\u308b\u3002\u5c40\u6240\u307e\u305f\u306f\u7d4c\u53e3NSAID\u3001\u30d1\u30e9\u30bb\u30bf\u30e2\u30fc\u30eb\uff08\u30a2\u30bb\u30c8\u30a2\u30df\u30ce\u30d5\u30a7\u30f3\uff09\u3001\u30aa\u30d4\u30aa\u30a4\u30c9\u304c\u4e00\u6b21\u85ac\u7269\u7642\u6cd5\u3068\u306a\u308b\u3002\u3053\u308c\u307e\u3067\u306e\u30a8\u30d3\u30c7\u30f3\u30b9\u3067\u306f\u3001\u75db\u307f\u3068\u8eab\u4f53\u6a5f\u80fd\u306e\u6539\u5584\u304c\u30aa\u30d4\u30aa\u30a4\u30c9\u3068NSAID\u3067\u4f3c\u901a\u3063\u3066\u3044\u308b\u53ef\u80fd\u6027\u3092\u793a\u5506\u3057\u3066\u3044\u308b\u304c\u3001\u30aa\u30d4\u30aa\u30a4\u30c9\u306f\u591a\u304f\u306e\u6709\u5bb3\u4e8b\u8c61\u3092\u5f15\u304d\u8d77\u3053\u3059\u3002\u30aa\u30d4\u30aa\u30a4\u30c9\u306b\u3088\u308b\u60aa\u5fc3\u30fb\u5614\u5410\u3001\u7720\u6c17\u306a\u3069\u306e\u526f\u4f5c\u7528\u306b\u52a0\u3048\u3066\u3001\u6162\u6027\u7684\u306a\u4f7f\u7528\u306b\u3088\u308a\u9aa8\u6298\u3001\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\u3001\u30aa\u30d4\u30aa\u30a4\u30c9\u4f9d\u5b58\u3001\u6b7b\u4ea1\u30ea\u30b9\u30af\u306e\u5897\u52a0\u3068\u95a2\u9023\u3057\u3066\u3044\u308b\u3002\u30ab\u30ca\u30c0\u3067\u306f2000\u5e74\u304b\u30892017\u5e74\u306e\u9593\u306b\u3001\u30aa\u30d4\u30aa\u30a4\u30c9\u95a2\u9023\u306e\u6b7b\u4ea1\u7387\u304c593\uff05\u5897\u52a0\u3057\u305f\u3002\u306b\u3082\u95a2\u308f\u3089\u305a\u3001\u30aa\u30d4\u30aa\u30a4\u30c9\u306f\u82f1\u56fd\u3001\u7c73\u56fd\u3001\u30ab\u30ca\u30c0\u3001\u30aa\u30fc\u30b9\u30c8\u30e9\u30ea\u30a2\u3067\u5909\u5f62\u6027\u95a2\u7bc0\u75c7\u306e\u75db\u307f\u306b\u5bfe\u3057\u3066\u6700\u3082\u51e6\u65b9\u3055\u308c\u3066\u3044\u308b\u85ac\u306e\u4e00\u3064\u3068\u306a\u3063\u3066\u3044\u308b\u3002<br \/>\n\u3000\u4ee5\u524d\u306e\u30b7\u30b9\u30c6\u30de\u30c6\u30a3\u30c3\u30af\u30ec\u30d3\u30e5\u30fc\u3067\u306f\u3001\u5909\u5f62\u6027\u95a2\u7bc0\u75c7\u306e\u75db\u307f\u306b\u5bfe\u3059\u308bNSAID\u3068\u30aa\u30d4\u30aa\u30a4\u30c9\u306e\u6709\u52b9\u6027\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u308b\u3002\u4e00\u65b9\u3001\u3053\u308c\u307e\u3067\u306e\u30ec\u30d3\u30e5\u30fc\u3067\u306f\u3001\u85ac\u5264\u306e\u6709\u52b9\u91cf\u306e\u4e2d\u3067\u6700\u4f4e\u7528\u91cf\u3092\u51e6\u65b9\u3059\u308b\u3001\u3068\u3044\u3046\u63a8\u5968\u4e8b\u9805\u3092\u5b9f\u65bd\u3059\u308b\u306e\u306b\u5341\u5206\u306a\u30a8\u30d3\u30c7\u30f3\u30b9\u306f\u5f97\u3089\u308c\u3066\u3044\u306a\u3044\u3002\u8a73\u7d30\u306a\u30a8\u30d3\u30c7\u30f3\u30b9\u3092\u63d0\u793a\u3057\u3001\u3088\u308a\u5b89\u5168\u306a\u51e6\u65b9\u3092\u53ef\u80fd\u306b\u3059\u308b\u305f\u3081\u306b\u3001\u819d\u3068\u80a1\u95a2\u7bc0\u306e\u5909\u5f62\u6027\u95a2\u7bc0\u75c7\u306e\u75db\u307f\u3068\u8eab\u4f53\u6a5f\u80fd\u306b\u5bfe\u3059\u308bNSAIDs\u3001\u30aa\u30d4\u30aa\u30a4\u30c9\u3001\u30d1\u30e9\u30bb\u30bf\u30e2\u30fc\u30eb\u306e\u69d8\u3005\u306a\u88fd\u5264\u3068\u7528\u91cf\u306e\u6709\u52b9\u6027\u3068\u5b89\u5168\u6027\u3092\u8a55\u4fa1\u3057\u305f\u3002<br \/>\nMethod\uff1a<br \/>\n\u30b7\u30b9\u30c6\u30de\u30c6\u30a3\u30c3\u30af\u30ec\u30d3\u30e5\u30fc\u3068\u30e1\u30bf\u30a2\u30ca\u30ea\u30b7\u30b9\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u306e\u512a\u5148\u30ec\u30dd\u30fc\u30c8\u9805\u76ee\u306b\u5f93\u3044\u3001\u819d\u307e\u305f\u306f\u80a1\u95a2\u7bc0\u306e\u5909\u5f62\u6027\u95a2\u7bc0\u75c7\u306e\u60a3\u8005\u306e\u5927\u898f\u6a21\u30e9\u30f3\u30c0\u30e0\u5316\u8a66\u9a13\u3092\u691c\u8a0e\u3057\u305f\u3002NSAID\u3001\u30aa\u30d4\u30aa\u30a4\u30c9\u3001\u30d1\u30e9\u30bb\u30bf\u30e2\u30fc\u30eb\u3001\u307e\u305f\u306f\u30d7\u30e9\u30bb\u30dc\u3002\u819d\u307e\u305f\u306f\u80a1\u95a2\u7bc0\u4ee5\u5916\u306e\u95a2\u7bc0\u708e\u3092\u542b\u3080\u8a66\u9a13\u306f\u3001\u60a3\u8005\u306e75\uff05\u4ee5\u4e0a\u304c\u819d\u307e\u305f\u306f\u80a1\u95a2\u7bc0\u306e\u5909\u5f62\u6027\u95a2\u7bc0\u75c7\u3092\u78ba\u8a8d\u3057\u305f\u5834\u5408\u306b\u306e\u307f\u542b\u307e\u308c\u305f\u3002<\/p>\n<p>Results\uff1a<br \/>\n102 829\u4eba\u306e\u53c2\u52a0\u8005\u304b\u3089\u306a\u308b192\u4ef6\u306e\u8a66\u9a13\u3067\u300190\u7a2e\u985e\u306e\u6709\u52b9\u306a\u88fd\u5264\u307e\u305f\u306f\u7528\u91cf\u304c\u691c\u8a0e\u3055\u308c\u305f\uff08NSAID\u3067\u306f68\u3001\u30aa\u30d4\u30aa\u30a4\u30c9\u3067\u306f19\u3001\u30d1\u30e9\u30bb\u30bf\u30e2\u30fc\u30eb\u3067\u306f3\uff09\u30025\u3064\u306e\u7d4c\u53e3\u88fd\u5264\uff08\u30b8\u30af\u30ed\u30d5\u30a7\u30ca\u30af150 mg \/\u65e5\u3001\u30a8\u30c8\u30ea\u30b3\u30ad\u30b7\u30d660\u304a\u3088\u307390 mg \/\u65e5\u3001\u30ed\u30d5\u30a7\u30b3\u30ad\u30b7\u30d625\u304a\u3088\u307350 mg \/\u65e5\uff09\u306f\u3001\u81e8\u5e8a\u7684\u306b\u95a2\u9023\u3059\u308b\u6700\u5c0f\u9650\u306e\u75db\u307f\u306e\u8efd\u6e1b\u3088\u308a\u3082\u6cbb\u7642\u52b9\u679c\u304c\u5927\u304d\u304f\u306a\u308b\u78ba\u7387\u304c99\uff05\u4ee5\u4e0a\u3060\u3063\u305f\u3002\u5c40\u6240\u30b8\u30af\u30ed\u30d5\u30a7\u30ca\u30af\uff0870-81\u304a\u3088\u3073140-160mg \/\u65e5\uff09\u306e\u78ba\u7387\u306f92.3\uff05\u4ee5\u4e0a\u3067\u3042\u308a\u3001\u3059\u3079\u3066\u306e\u30aa\u30d4\u30aa\u30a4\u30c9\u306f\u3001\u81e8\u5e8a\u7684\u306b\u95a2\u9023\u3059\u308b\u6700\u5c0f\u9650\u306e\u75db\u307f\u306e\u8efd\u6e1b\u3088\u308a\u3082\u6cbb\u7642\u52b9\u679c\u304c\u5927\u304d\u304f\u306a\u308b\u78ba\u7387\u304c53\uff05\u4ee5\u4e0b\u3060\u3063\u305f\u3002\u7d4c\u53e3NSAID\u3001\u5c40\u6240NSAID\u3001\u304a\u3088\u3073\u30aa\u30d4\u30aa\u30a4\u30c9\u306e\u305d\u308c\u305e\u308c18.5\uff05\u30010\uff05\u300183.3\uff05\u306f\u3001\u6709\u5bb3\u4e8b\u8c61\u306b\u3088\u308b\u8131\u843d\u306e\u30ea\u30b9\u30af\u304c\u5897\u52a0\u3057\u3066\u3044\u305f\u3002\u7d4c\u53e3NSAID\u3001\u5c40\u6240NSAID\u3001\u304a\u3088\u3073\u30aa\u30d4\u30aa\u30a4\u30c9\u306e\u305d\u308c\u305e\u308c29.8\uff05\u30010\uff05\u3001\u304a\u3088\u307389.5\uff05\u3067\u3001\u6709\u5bb3\u4e8b\u8c61\u306e\u30ea\u30b9\u30af\u304c\u5897\u52a0\u3057\u305f\u3002<\/p>\n<p>Discussion\uff1a<br \/>\n\u30a8\u30c8\u30ea\u30b3\u30ad\u30b7\u30d660mg \/\u65e5\u3068\u30b8\u30af\u30ed\u30d5\u30a7\u30ca\u30af150mg \/\u65e5\u306f\u3001\u5909\u5f62\u6027\u95a2\u7bc0\u75c7\u60a3\u8005\u306e\u75db\u307f\u3068\u6a5f\u80fd\u306b\u6700\u3082\u52b9\u679c\u7684\u306a\u7d4c\u53e3NSAID\u3067\u3042\u308b\u3088\u3046\u3002\u305f\u3060\u3057\u3001\u3053\u308c\u3089\u306e\u6cbb\u7642\u6cd5\u306f\u3001\u6709\u5bb3\u4e8b\u8c61\u306e\u30ea\u30b9\u30af\u304c\u308f\u305a\u304b\u306b\u5897\u52a0\u3059\u308b\u305f\u3081\u3001\u4f75\u5b58\u75c7\u306e\u3042\u308b\u60a3\u8005\u3084\u9577\u671f\u4f7f\u7528\u306b\u306f\u304a\u305d\u3089\u304f\u9069\u5207\u3067\u306f\u306a\u3044\u3002\u3055\u3089\u306b\u3001\u6709\u5bb3\u4e8b\u8c61\u306b\u3088\u308b\u8131\u843d\u306e\u30ea\u30b9\u30af\u306e\u5897\u52a0\u306f\u3001\u30b8\u30af\u30ed\u30d5\u30a7\u30ca\u30af150mg \/\u65e5\u3067\u591a\u304f\u307f\u3089\u308c\u305f\u3002\u5c40\u6240\u30b8\u30af\u30ed\u30d5\u30a7\u30ca\u30af70-81mg \/\u65e5\u306f\u3001\u5168\u8eab\u66dd\u9732\u306e\u6e1b\u5c11\u3068\u4f4e\u7528\u91cf\u306e\u305f\u3081\u3001\u52b9\u679c\u7684\u3067\u3001\u4e00\u822c\u7684\u306b\u5b89\u5168\u3067\u3042\u308a\u3001\u5909\u5f62\u6027\u819d\u95a2\u7bc0\u75c7\u306e\u7b2c\u4e00\u9078\u629e\u306e\u85ac\u7406\u5b66\u7684\u6cbb\u7642\u3068\u3057\u3066\u8003\u616e\u3055\u308c\u308b\u3079\u304d\u3067\u3042\u308b\u3002\u30aa\u30d4\u30aa\u30a4\u30c9\u6cbb\u7642\u306e\u81e8\u5e8a\u7684\u5229\u70b9\u306f\u3001\u6e96\u5099\u3084\u6295\u4e0e\u91cf\u306b\u95a2\u4fc2\u306a\u304f\u3001\u5909\u5f62\u6027\u95a2\u7bc0\u75c7\u306e\u60a3\u8005\u306b\u5f15\u304d\u8d77\u3053\u3059\u53ef\u80fd\u6027\u306e\u3042\u308b\u5bb3\u3092\u4e0a\u56de\u3063\u3066\u3044\u306a\u3044\u3002<\/p>\n<p><a href=\"https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2023\/03\/d6e6af4685b5022ee0c9efad4156cda5.jpg\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2023\/03\/d6e6af4685b5022ee0c9efad4156cda5.jpg\" alt=\"\" width=\"1593\" height=\"2000\" class=\"aligncenter size-full wp-image-2267\" srcset=\"https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2023\/03\/d6e6af4685b5022ee0c9efad4156cda5.jpg 1593w, https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2023\/03\/d6e6af4685b5022ee0c9efad4156cda5-239x300.jpg 239w, https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2023\/03\/d6e6af4685b5022ee0c9efad4156cda5-816x1024.jpg 816w, https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2023\/03\/d6e6af4685b5022ee0c9efad4156cda5-768x964.jpg 768w, https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2023\/03\/d6e6af4685b5022ee0c9efad4156cda5-1223x1536.jpg 1223w\" sizes=\"auto, (max-width: 1593px) 100vw, 1593px\" \/><\/a><br \/>\nFig2\uff1a\u5909\u5f62\u6027\u95a2\u7bc0\u75c7\u306e\u75db\u307f\u306b\u5bfe\u3059\u308b\u6cbb\u7642\u52b9\u679c\u306e\u5927\u304d\u3055\u306b\u5f93\u3063\u3066\u9806\u5e8f\u4ed8\u3051\u3089\u308c\u305f\u3001\u7d4c\u53e3\u30d7\u30e9\u30bb\u30dc\u3068\u6bd4\u8f03\u3057\u305f\u6709\u5bb3\u4e8b\u8c61\u306b\u3088\u308b\u5909\u5f62\u6027\u95a2\u7bc0\u75c7\u306e\u75db\u307f\u304a\u3088\u3073\u8131\u843d\u306b\u5bfe\u3059\u308b\u6cbb\u7642\u52b9\u679c\u3002\u9752\uff1a\u7d4c\u53e3\u975e\u30b9\u30c6\u30ed\u30a4\u30c9\u6027\u6297\u708e\u75c7\u85ac; \u7dd1\uff1a\u5c40\u6240\u975e\u30b9\u30c6\u30ed\u30a4\u30c9\u6027\u6297\u708e\u75c7\u85ac; \u30aa\u30ec\u30f3\u30b8\uff1a\u30aa\u30d4\u30aa\u30a4\u30c9\u3002<\/p>\n<p><a href=\"https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2023\/03\/918177c73603e11af0f09a398695925d.jpg\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2023\/03\/918177c73603e11af0f09a398695925d.jpg\" alt=\"\" width=\"2000\" height=\"1908\" class=\"aligncenter size-full wp-image-2268\" srcset=\"https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2023\/03\/918177c73603e11af0f09a398695925d.jpg 2000w, https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2023\/03\/918177c73603e11af0f09a398695925d-300x286.jpg 300w, https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2023\/03\/918177c73603e11af0f09a398695925d-1024x977.jpg 1024w, https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2023\/03\/918177c73603e11af0f09a398695925d-768x733.jpg 768w, https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2023\/03\/918177c73603e11af0f09a398695925d-1536x1465.jpg 1536w\" sizes=\"auto, (max-width: 2000px) 100vw, 2000px\" \/><\/a><br \/>\nFig3\uff1a\u56f32\u306e\u7d9a\u304d\u3002\u5909\u5f62\u6027\u95a2\u7bc0\u75c7\u306e\u75db\u307f\u306b\u5bfe\u3059\u308b\u6cbb\u7642\u52b9\u679c\u306e\u5927\u304d\u3055\u306b\u5f93\u3063\u3066\u9806\u5e8f\u4ed8\u3051\u3089\u308c\u305f\u3001\u7d4c\u53e3\u30d7\u30e9\u30bb\u30dc\u3068\u6bd4\u8f03\u3057\u305f\u6709\u5bb3\u4e8b\u8c61\u306b\u3088\u308b\u5909\u5f62\u6027\u95a2\u7bc0\u75c7\u306e\u75db\u307f\u304a\u3088\u3073\u8131\u843d\u306b\u5bfe\u3059\u308b\u6cbb\u7642\u52b9\u679c\u3002\u9752\uff1a\u7d4c\u53e3\u975e\u30b9\u30c6\u30ed\u30a4\u30c9\u6027\u6297\u708e\u75c7\u85ac; \u7dd1\uff1a\u5c40\u6240\u975e\u30b9\u30c6\u30ed\u30a4\u30c9\u6027\u6297\u708e\u75c7\u85ac; \u30aa\u30ec\u30f3\u30b8\uff1a\u30aa\u30d4\u30aa\u30a4\u30c9; \u30d4\u30f3\u30af\uff1a\u30d1\u30e9\u30bb\u30bf\u30e2\u30fc\u30eb; \u9ed2\uff1a\u30d7\u30e9\u30bb\u30dc\u3002<\/p>\n<p><a href=\"https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2023\/03\/94758c85acffb26f68b88271b4a8ca35.jpg\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2023\/03\/94758c85acffb26f68b88271b4a8ca35.jpg\" alt=\"\" width=\"1056\" height=\"572\" class=\"aligncenter size-full wp-image-2269\" srcset=\"https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2023\/03\/94758c85acffb26f68b88271b4a8ca35.jpg 1056w, https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2023\/03\/94758c85acffb26f68b88271b4a8ca35-300x163.jpg 300w, https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2023\/03\/94758c85acffb26f68b88271b4a8ca35-1024x555.jpg 1024w, https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2023\/03\/94758c85acffb26f68b88271b4a8ca35-768x416.jpg 768w\" sizes=\"auto, (max-width: 1056px) 100vw, 1056px\" \/><\/a><br \/>\nFig4\uff1a\u7d4c\u53e3\u30d7\u30e9\u30bb\u30dc\u3068\u6bd4\u8f03\u3057\u3066\u81e8\u5e8a\u7684\u306b\u91cd\u8981\u306a\u5dee\u7570\u304c\u6700\u5c0f\u3067\u3042\u308b\u85ac\u5264\u306e\u78ba\u7387\u3068\u3001\u6709\u5bb3\u4e8b\u8c61\u306e\u305f\u3081\u306b\u53c2\u52a0\u8005\u304c\u6cbb\u7642\u3092\u4e2d\u65ad\u3059\u308b\u78ba\u7387\u3092\u793a\u30592\u6b21\u5143\u30b0\u30e9\u30d5\u3002\u6709\u5bb3\u4e8b\u8c61\u306b\u3088\u308a\u7d4c\u53e3\u30d7\u30e9\u30bb\u30dc\u304c\u8131\u843d\u3059\u308b\u78ba\u7387\u306f5\uff05\u3002MID =\u30b0\u30eb\u30fc\u30d7\u9593\u306e\u81e8\u5e8a\u7684\u306b\u91cd\u8981\u306a\u6700\u5c0f\u306e\u5dee\u3002<\/p>\n<p>\u3010\u958b\u50ac\u65e5\u3011<br \/>\n2021\u5e7412\u67081\u65e5\uff08\u6c34\uff09<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u2015\u6587\u732e\u540d\u2015 Bruno R da Costa. Effectiveness and safety of non-steroidal anti-inflammatory drugs and opioid treatment &hellip; <a href=\"https:\/\/www.hcfm.jp\/journal\/?p=2266\" class=\"more-link\">\u7d9a\u304d\u3092\u8aad\u3080 <span class=\"screen-reader-text\">\u5909\u5f62\u6027\u819d\u30fb\u80a1\u95a2\u7bc0\u75c7\u3078\u306eNSAIDs\u3001\u30aa\u30d4\u30aa\u30a4\u30c9\u6cbb\u7642\u306e\u6709\u52b9\u6027\u3068\u5b89\u5168\u6027<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[17],"tags":[],"class_list":["post-2266","post","type-post","status-publish","format-standard","hentry","category-17"],"_links":{"self":[{"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/posts\/2266","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2266"}],"version-history":[{"count":1,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/posts\/2266\/revisions"}],"predecessor-version":[{"id":2270,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/posts\/2266\/revisions\/2270"}],"wp:attachment":[{"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2266"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=2266"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=2266"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}