{"id":2363,"date":"2023-05-18T10:30:46","date_gmt":"2023-05-18T01:30:46","guid":{"rendered":"https:\/\/www.hcfm.jp\/journal\/?p=2363"},"modified":"2023-05-18T10:30:46","modified_gmt":"2023-05-18T01:30:46","slug":"16%e3%82%ab%e5%9b%bd%e3%81%ab%e3%81%8a%e3%81%91%e3%82%8b%e3%83%92%e3%83%88%e3%81%ae%e3%82%b5%e3%83%ab%e7%97%98%e3%82%a6%e3%82%a4%e3%83%ab%e3%82%b9%e6%84%9f%e6%9f%93","status":"publish","type":"post","link":"https:\/\/www.hcfm.jp\/journal\/?p=2363","title":{"rendered":"16\u30ab\u56fd\u306b\u304a\u3051\u308b\u30d2\u30c8\u306e\u30b5\u30eb\u75d8\u30a6\u30a4\u30eb\u30b9\u611f\u67d3"},"content":{"rendered":"

\uff0d\u6587\u732e\u540d\uff0d
\nJohn P. Thornhill. et al. Monkeypox Virus Infection in Humans across 16 Countries \u2014 April\u2013June 2022. NEJM. July 21, 2022<\/p>\n

\uff0d\u8981\u7d04\uff0d
\nIntroduction\/Background
\n2022\u5e744\u6708\u4ee5\u524d\u306f\u3001\u30d2\u30c8\u306e\u30b5\u30eb\u75d8\u30a6\u30a4\u30eb\u30b9\u611f\u67d3\u306f\u3001\u6d41\u884c\u3057\u3066\u3044\u308b\u30a2\u30d5\u30ea\u30ab\u5730\u57df\u4ee5\u5916\u3067\u306f\u3001\u307b\u3068\u3093\u3069\u5831\u544a\u304c\u306a\u304b\u3063\u305f\u3002\u73fe\u5728\u306f\u3001\u4e16\u754c\u4e2d\u3067\u75c7\u4f8b\u304c\u767a\u751f\u3057\u3066\u3044\u308b\u3002\u3057\u304b\u3057\u3001\u4f1d\u67d3\u3001\u5371\u967a\u56e0\u5b50\u3001\u81e8\u5e8a\u75c7\u72b6\u3001\u304a\u3088\u3073\u611f\u67d3\u306e\u8ee2\u5e30\u306f\u5341\u5206\u306b\u5b9a\u7fa9\u3055\u308c\u3066\u3044\u306a\u3044\u3002<\/p>\n

Method
\n\u79c1\u305f\u3061\u306f\u3001\u81e8\u5e8a\u533b\u306e\u56fd\u969b\u5171\u540c\u30b0\u30eb\u30fc\u30d7\u3092\u7d50\u6210\u3057\u3001\u30dd\u30ea\u30e1\u30e9\u30fc\u30bc\u9023\u9396\u53cd\u5fdc\uff08PCR\uff09\u3067\u78ba\u8a8d\u3055\u308c\u305f\u30b5\u30eb\u75d8\u30a6\u30a4\u30eb\u30b9\u611f\u67d3\u75c7\u306e\u75c7\u72b6\u3001\u81e8\u5e8a\u7d4c\u904e\u3001\u8ee2\u5e30\u3092\u8aac\u660e\u3059\u308b\u305f\u3081\u306e\u56fd\u969b\u75c7\u4f8b\u30b7\u30ea\u30fc\u30ba\u4f5c\u6210\u306b\u8ca2\u732e\u3057\u305f\u3002<\/p>\n

Result
\n\u30002022\u5e744\u670827\u65e5\u304b\u30896\u670824\u65e5\u306e\u9593\u306b16\u304b\u56fd\u306e43\u304b\u6240\u3067\u8a3a\u65ad\u3055\u308c\u305f 528 \u4ef6\u306e\u611f\u67d3\u3092\u5831\u544a\u3059\u308b\u3002\u5168\u4f53\u3068\u3057\u3066\u3001\u611f\u67d3\u8005\u306e98%\u304c\u3001\u30b2\u30a4\u307e\u305f\u306f\u30d0\u30a4\u30bb\u30af\u30b7\u30e5\u30a2\u30eb\u306e\u7537\u6027\u3067\u300175%\u304c\u767d\u4eba\u3067\u300141%\u304c\u30d2\u30c8\u514d\u75ab\u4e0d\u5168\u30a6\u30a4\u30eb\u30b9\uff08HIV\uff09\u306b\u611f\u67d3\u3057\u3066\u3044\u305f\u3002\u5e74\u9f62\u306e\u4e2d\u592e\u5024\u306f38\u6b73\u3060\u3063\u305f\u3002\u4f1d\u67d3\u306f\u3001\u611f\u67d3\u8005\u306e95%\u3067\u6027\u884c\u70ba\u3092\u4ecb\u3057\u3066\u767a\u751f\u3057\u305f\u7591\u3044\u304c\u3042\u3063\u305f\u3002\u3053\u306e\u75c7\u4f8b\u30b7\u30ea\u30fc\u30ba\u3067\u306f\u300195%\u306e\u4eba\u306b\u767a\u75b9\u304c\u3042\u308a\uff0864%\u306f10\u500b\u672a\u6e80\u306e\u75c5\u5909\uff09\u300173%\u306f\u809b\u9580\u6027\u5668\u75c5\u5909\u300141%\u306f\u7c98\u819c\u75c5\u5909 (54\u4eba\u306f\u5358\u4e00\u306e\u6027\u5668\u75c5\u5909)\u3060\u3063\u305f\u3002\u767a\u75b9\u306b\u5148\u884c\u3059\u308b\u4e00\u822c\u7684\u306a\u5168\u8eab\u7684\u7279\u5fb4\u306b\u306f\u3001\u767a\u71b1 (62%)\u3001\u7121\u6c17\u529b (41%)\u3001\u7b4b\u8089\u75db (31%)\u3001\u304a\u3088\u3073\u982d\u75db (27%) \u304c\u542b\u307e\u308c\u3066\u3044\u305f\u3002\u30ea\u30f3\u30d1\u7bc0\u816b\u8139\uff0856%\uff09\u3082\u4e00\u822c\u7684\u3060\u3063\u305f\u3002\u691c\u67fb\u3092\u53d7\u3051\u305f377\u4eba\u4e2d109\u4eba (29%) \u3067\u6027\u611f\u67d3\u75c7\u306e\u4f75\u767a\u304c\u5831\u544a\u3055\u308c\u305f\u3002\u66b4\u9732\u6b74\u304c\u660e\u3089\u304b\u306a23\u4eba\u306e\u3046\u3061\u3001\u6f5c\u4f0f\u671f\u9593\u306e\u4e2d\u592e\u5024\u306f7\u65e5 (\u7bc4\u56f2\uff1a3\uff5e20\u65e5) \u3060\u3063\u305f\u3002\u30b5\u30eb\u75d8\u30a6\u30a4\u30eb\u30b9DNA\u306f\u3001\u7cbe\u6db2\u3092\u5206\u6790\u3057\u305f32\u4eba\u4e2d29 \u4eba\u3067\u691c\u51fa\u3055\u308c\u305f\u3002\u5168\u4f53\u306e5%\u306e\u4eba\u306b\u6297\u30a6\u30a4\u30eb\u30b9\u6cbb\u7642\u304c\u65bd\u3055\u308c\u300170\u4eba (13%) \u304c\u5165\u9662\u3057\u305f\u3002\u5165\u9662\u306e\u7406\u7531\u306f\u75bc\u75db\u7ba1\u7406\u3067\u3001\u4e3b\u306b\u809b\u9580\u76f4\u8178\u306e\u91cd\u5ea6\u306e\u75db\u307f\uff0821\u4eba\uff09\u3067\u3042\u3063\u305f\u3002\u8edf\u90e8\u7d44\u7e54\u91cd\u8907\u611f\u67d3 (18\u4eba); \u7d4c\u53e3\u6442\u53d6\u3092\u5236\u9650\u3059\u308b\u54bd\u982d\u708e (5\u4eba); \u773c\u75c5\u5909 (2\u4eba); \u6025\u6027\u814e\u969c\u5bb3 (2\u4eba); \u5fc3\u7b4b\u708e (2\u4eba); \u304a\u3088\u3073\u611f\u67d3\u5236\u5fa1\u76ee\u7684\uff0813\u4eba\uff09\u3002\u6b7b\u4ea1\u4f8b\u306f\u5831\u544a\u3055\u308c\u3066\u3044\u306a\u3044\u3002<\/p>\n

Discussion
\n\u3000\u6027\u884c\u70ba\u306f\u3001\u4e3b\u306b\u30b2\u30a4\u307e\u305f\u306f\u30d0\u30a4\u30bb\u30af\u30b7\u30e5\u30a2\u30eb\u306e\u7537\u6027\u306e\u9593\u3067\u6700\u3082\u983b\u7e41\u306b\u7591\u308f\u308c\u308b\u611f\u67d3\u7d4c\u8def\u3060\u3063\u305f\u3002\u6027\u7684\u611f\u67d3\u306e\u53ef\u80fd\u6027\u304c\u9ad8\u3044\u3053\u3068\u306f\u3001\u63a5\u7a2e\u90e8\u4f4d\u3092\u8868\u3059\u53ef\u80fd\u6027\u306e\u3042\u308b\u539f\u767a\u6027\u751f\u6b96\u5668\u3001\u809b\u9580\u3001\u304a\u3088\u3073\u53e3\u8154\u7c98\u819c\u75c5\u5909\u306e\u6240\u898b\u306b\u3088\u3063\u3066\u88cf\u4ed8\u3051\u3089\u308c\u305f\u3002\u7cbe\u6db2\u3092\u691c\u67fb\u3057\u305f32\u4f8b\u4e2d29\u4f8b\u3067\u7cbe\u6db2\u4e2d\u306ePCR\u306b\u3088\u3063\u3066\u691c\u51fa\u3055\u308c\u305f\u30b5\u30eb\u75d8\u30a6\u30a4\u30eb\u30b9DNA\u306f\u3001\u3053\u306e\u4eee\u8aac\u3092\u3055\u3089\u306b\u652f\u6301\u3059\u308b\u3002\u3057\u304b\u3057\u3001\u3053\u308c\u3089\u306e\u6a19\u672c\u3067\u691c\u51fa\u3055\u308c\u305f\u30a6\u30a4\u30eb\u30b9DNA\u304c\u8907\u88fd\u53ef\u80fd\u3067\u3042\u3063\u305f\u304b\u3069\u3046\u304b\u306f\u4e0d\u660e\u3067\u3042\u308b\u305f\u3081\u3001\u7cbe\u6db2\u304c\u611f\u67d3\u3092\u4f1d\u9054\u3067\u304d\u308b\u304b\u3069\u3046\u304b\u306f\u307e\u3060\u8abf\u67fb\u3055\u308c\u3066\u3044\u306a\u3044\u3002\u30bb\u30c3\u30af\u30b9\u30d1\u30fc\u30c6\u30a3\u30fc\u3084\u30b5\u30a6\u30ca\u306b\u95a2\u9023\u3059\u308b\u96c6\u56e3\u767a\u751f\u306e\u5831\u544a\u306f\u3001\u6027\u7684\u63a5\u89e6\u304c\u4f1d\u67d3\u306e\u4fc3\u9032\u56e0\u5b50\u3068\u3057\u3066\u6f5c\u5728\u7684\u306a\u5f79\u5272\u3092\u679c\u305f\u3057\u3066\u3044\u308b\u3053\u3068\u3092\u3055\u3089\u306b\u5f37\u8abf\u3057\u3066\u3044\u308b\u3002\u6d77\u5916\u65c5\u884c\u3084\u73fe\u5834\u3067\u306e\u6027\u884c\u70ba\u306b\u95a2\u9023\u3059\u308b\u5927\u898f\u6a21\u306a\u96c6\u4f1a\u3078\u306e\u53c2\u52a0\u306f\u3001\u6027\u7684\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u3092\u901a\u3058\u3066\u5897\u5e45\u3055\u308c\u305f\u30b5\u30eb\u75d8\u611f\u67d3\u306e\u4e16\u754c\u7684\u306a\u5e83\u304c\u308a\u3092\u8aac\u660e\u3059\u308b\u304b\u3082\u3057\u308c\u306a\u3044\u3002
\n\u79c1\u305f\u3061\u304c\u8aac\u660e\u3059\u308b\u81e8\u5e8a\u75c7\u72b6\u306b\u306f\u3001\u56fd\u969b\u7684\u306b\u53d7\u3051\u5165\u308c\u3089\u308c\u3066\u3044\u308b\u75c7\u4f8b\u5b9a\u7fa9\u306b\u306f\u542b\u307e\u308c\u3066\u3044\u306a\u3044\u3044\u304f\u3064\u304b\u306e\u660e\u78ba\u306a\u7279\u5fb4\u304c\u3042\u308b\u3002\u3053\u308c\u3089\u306e\u5b9a\u7fa9\u306f\u6700\u8fd1\u3001\u30b2\u30a4\u307e\u305f\u306f\u30d0\u30a4\u30bb\u30af\u30b7\u30e5\u30a2\u30eb\u306e\u7537\u6027\u3001\u304a\u3088\u3073\u30ea\u30b9\u30af\u30b0\u30eb\u30fc\u30d7\u3068\u3057\u3066\u7537\u6027\u3068\u30bb\u30c3\u30af\u30b9\u3092\u3059\u308b\u4ed6\u306e\u7537\u6027\u3092\u542b\u3080\u3088\u3046\u306b\u62e1\u5927\u3055\u308c\u305f\u304c\u3001\u7c98\u819c\u307e\u305f\u306f\u76f4\u8178\u306e\u75c7\u72b6\u3092\u7279\u306b\u5f37\u8abf\u3057\u3066\u3044\u306a\u3044\u3002\u307e\u305f\u3001\u6700\u521d\u306e\u5358\u4e00\u75c5\u5909\u306e\u75c7\u72b6\u306e\u53ef\u80fd\u6027\u306b\u3064\u3044\u3066\u8b66\u544a\u3057\u3066\u3044\u306a\u3044\u3002\u65e2\u5b58\u306e\u5b9a\u7fa9\u3067\u306f\u3001\u7570\u5e38\u306a\u767a\u75b9\u306e\u6587\u8108\u3067\u30b5\u30eb\u75d8\u3092\u8003\u616e\u3059\u308b\u3053\u3068\u3092\u63a8\u5968\u3057\u3066\u3044\u308b\u304c\u3001\u8003\u3048\u3089\u308c\u308b\u75c7\u72b6\u306e\u5168\u7bc4\u56f2\u3092\u30ab\u30d0\u30fc\u3057\u3066\u3044\u306a\u3044\u3002\u5b64\u7acb\u6027\u751f\u6b96\u5668\u306e\u76ae\u819a\u75c5\u5909\u3084\u624b\u306e\u3072\u3089\u3084\u8db3\u306e\u88cf\u306e\u75c5\u5909\u306f\u3001\u6885\u6bd2\u3084\u305d\u306e\u4ed6\u306e\u6027\u611f\u67d3\u75c7\u3068\u8aa4\u8a3a\u3055\u308c\u3084\u3059\u304f\u3001\u691c\u51fa\u304c\u9045\u308c\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3002\u4ed8\u968f\u3059\u308b\u691c\u67fb\u5ba4\u3067\u78ba\u8a8d\u3055\u308c\u305f\u6027\u611f\u67d3\u75c7\u3082\u3001\u691c\u67fb\u3092\u53d7\u3051\u305f\u4eba\u306e29% \u3067\u5831\u544a\u3055\u308c\u305f\u3002\u3057\u305f\u304c\u3063\u3066\u3001\u4f1d\u7d71\u7684\u306a\u6027\u611f\u67d3\u75c7\u306e\u75c7\u72b6\u3092\u5448\u3059\u308b\u30ea\u30b9\u30af\u306e\u3042\u308b\u4eba\u306b\u306f\u3001\u30b5\u30eb\u75d8\u3092\u8003\u616e\u3059\u308b\u3053\u3068\u3092\u52e7\u3081\u308b\u3002
\n\u79c1\u305f\u3061\u306e\u30b7\u30ea\u30fc\u30ba\u3067\u306f\u3001\u30b5\u30eb\u75d8\u306e\u8a3a\u65ad\u306f\u3001\u76ae\u819a\u307e\u305f\u306f\u751f\u6b96\u5668\u306e\u75c5\u5909\u304b\u3089\u63a1\u53d6\u3055\u308c\u305f\u7dbf\u68d2\u6a19\u672c\u304b\u3089\u6700\u3082\u4e00\u822c\u7684\u306b\u78ba\u8a8d\u3055\u308c\u305f\u3002\u5589\u307e\u305f\u306f\u9f3b\u54bd\u982d\u306e\u7dbf\u68d2\u6a19\u672c\u3068\u8840\u6db2\u306f\u3042\u307e\u308a\u4e00\u822c\u7684\u306b\u691c\u67fb\u3055\u308c\u3066\u3044\u306a\u3044\u3002\u809b\u9580\u306e\u75db\u307f\u3084\u76f4\u8178\u708e\u3092\u5448\u3059\u308b\u4eba\u306b\u306f\u3001\u809b\u9580\u307e\u305f\u306f\u76f4\u8178\u306e\u30b9\u30ef\u30d6\u3092\u8003\u616e\u3059\u308b\u5fc5\u8981\u304c\u3042\u308b\u3002
\n\u3053\u306e\u75c7\u4f8b\u30b7\u30ea\u30fc\u30ba\u306e\u81e8\u5e8a\u8ee2\u5e30\u306f\u5fc3\u5f37\u3044\u3082\u306e\u3060\u3063\u305f\u3002\u307b\u3068\u3093\u3069\u306e\u75c7\u4f8b\u306f\u8efd\u75c7\u3067\u81ea\u7136\u6cbb\u7652\u3057\u3001\u6b7b\u4ea1\u4f8b\u306f\u306a\u304b\u3063\u305f\u3002\u60a3\u8005\u306e 13%\u304c\u5165\u9662\u3057\u305f\u304c\u3001\u5165\u9662\u3057\u305f\u60a3\u8005\u306e\u5927\u534a\u3067\u6df1\u523b\u306a\u5408\u4f75\u75c7\u306f\u5831\u544a\u3055\u308c\u3066\u3044\u306a\u3044\u3002\u5165\u9662\u306e\u4e00\u822c\u7684\u306a\u7406\u7531\u306f\u3001\u75db\u307f\u3068\u7d30\u83cc\u306e\u91cd\u8907\u611f\u67d3\u3060\u3063\u305f\u3002\u305f\u3060\u3057\u3001\u307e\u308c\u306b\u6df1\u523b\u306a\u5408\u4f75\u75c7\uff08\u5fc3\u7b4b\u708e\u3068\u5589\u982d\u84cb\u708e\uff09\u304c\u89b3\u5bdf\u3055\u308c\u305f\u305f\u3081\u3001\u30d5\u30a9\u30ed\u30fc\u30a2\u30c3\u30d7\u671f\u9593\u304c\u77ed\u3044\u3053\u3068\u3092\u8003\u3048\u308b\u3068\u3001\u7279\u306b\u9577\u671f\u306b\u308f\u305f\u3063\u3066\u3001\u75be\u60a3\u3068\u5408\u4f75\u75c7\u306e\u5168\u7bc4\u56f2\u3092\u3055\u3089\u306b\u7814\u7a76\u3059\u308b\u5fc5\u8981\u304c\u3042\u308b\u3002\u30b5\u30eb\u75d8\u306e\u81e8\u5e8a\u75c7\u72b6\u3068\u91cd\u75c7\u5ea6\u306f\u3001HIV\u611f\u67d3\u306e\u6709\u7121\u306b\u304b\u304b\u308f\u3089\u305a\u4f3c\u3066\u3044\u308b\u3088\u3046\u306b\u898b\u3048\u305f\u304c\u3001HIV\u306b\u611f\u67d3\u3057\u305f\u79c1\u305f\u3061\u306e\u30b7\u30ea\u30fc\u30ba\u306e\u307b\u3068\u3093\u3069\u3059\u3079\u3066\u306e\u4eba\u3067\u3001HIV\u306f\u5341\u5206\u306b\u5236\u5fa1\u3055\u308c\u3066\u304a\u308a\u3001CD4\u7d30\u80de\u6570\u306e\u4e2d\u592e\u5024\u306f1\u7acb\u65b9\u30df\u30ea\u30e1\u30fc\u30c8\u30eb\u3042\u305f\u308a680\u7d30\u80de\u3060\u3063\u305f\u3002
\n\u3054\u304f\u4e00\u90e8\u306e\u4eba(5%)\u304c\u6297\u30a6\u30a4\u30eb\u30b9\u7642\u6cd5\u3092\u53d7\u3051\u3001\u307b\u3068\u3093\u3069\u306e\u5834\u5408\u3001\u30b7\u30c9\u30d5\u30a9\u30d3\u30eb\u307e\u305f\u306f\u30c6\u30b3\u30d3\u30ea\u30de\u30c3\u30c8\u304c\u4f7f\u7528\u3055\u308c\u305f\u3002\u30d2\u30c8\u306b\u304a\u3051\u308b\u3053\u308c\u3089\u306e\u5316\u5408\u7269\u306e\u6709\u52b9\u6027\u306b\u95a2\u3059\u308b\u30c7\u30fc\u30bf\u306f\u9650\u3089\u308c\u3066\u3044\u308b\u304c\u3001\u52d5\u7269\u3067\u306e\u7814\u7a76\u304a\u3088\u3073\u75c7\u4f8b\u5831\u544a\u306f\u3001\u305d\u308c\u3089\u304c\u6709\u52b9\u3067\u3042\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3053\u3068\u3092\u793a\u5506\u3057\u3066\u3044\u308b\u3002\u3053\u306e\u75c7\u4f8b\u30b7\u30ea\u30fc\u30ba\u3067\u306f\u300156\u4eba\u304c50\u6b73\u4ee5\u4e0a\u3067\u3001\u5168\u4f53\u30679%\u304c\u4ee5\u524d\u306b\u5929\u7136\u75d8\u306e\u4e88\u9632\u63a5\u7a2e\u3092\u53d7\u3051\u305f\u3068\u5831\u544a\u3057\u3066\u3044\u308b\u305f\u3081\u3001\u305d\u306e\u52b9\u679c\u306b\u3064\u3044\u3066\u30b3\u30e1\u30f3\u30c8\u3059\u308b\u3053\u3068\u306f\u3067\u304d\u306a\u3044\u3002
\n\u533b\u7642\u306e\u5c02\u9580\u5bb6\u306f\u3001\u30b5\u30eb\u75d8\u306e\u75c7\u4f8b\u3092\u8a8d\u8b58\u3057\u3066\u7ba1\u7406\u3059\u308b\u305f\u3081\u306e\u6559\u80b2\u3092\u53d7\u3051\u308b\u5fc5\u8981\u304c\u3042\u308b\u3002\u5371\u967a\u306b\u3055\u3089\u3055\u308c\u3066\u3044\u308b\u96c6\u56e3\u306e\u691c\u67fb\u3084\u6559\u80b2\u3092\u614e\u91cd\u306b\u30b5\u30dd\u30fc\u30c8\u3059\u308b\u7684\u3092\u7d5e\u3063\u305f\u5065\u5eb7\u5897\u9032\u304c\u5fc5\u8981\u3067\u3042\u308b\u3002\u516c\u8846\u885b\u751f\u4ecb\u5165\u306e\u5b9f\u65bd\u3092\u5f62\u6210\u3059\u308b\u969b\u306b\u30b3\u30df\u30e5\u30cb\u30c6\u30a3\u3092\u6700\u521d\u304b\u3089\u95a2\u4e0e\u3055\u305b\u308b\u3053\u3068\u306f\u3001\u305d\u308c\u3089\u304c\u9069\u5207\u3067\u504f\u898b\u306e\u306a\u3044\u3082\u306e\u3067\u3042\u308b\u3053\u3068\u3092\u4fdd\u8a3c\u3057\u3001\u30a2\u30a6\u30c8\u30d6\u30ec\u30a4\u30af\u3092\u5730\u4e0b\u306b\u8ffd\u3044\u3084\u308b\u30e1\u30c3\u30bb\u30fc\u30b8\u3092\u56de\u907f\u3059\u308b\u305f\u3081\u306b\u4e0d\u53ef\u6b20\u3067\u3042\u308b\u3002\u75c5\u5909\u304c\u6d88\u5931\u3057\u305f\u5f8c\u306e\u6f5c\u5728\u7684\u306a\u611f\u67d3\u6027\u30a6\u30a4\u30eb\u30b9\u6392\u51fa\u306e\u671f\u9593\u306f\u4e0d\u660e\u3067\u3042\u308b\u3002UKHSA \u306e\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u3067\u306f\u3001\u611f\u67d3\u5f8c8\u9031\u9593\u306f\u30b3\u30f3\u30c9\u30fc\u30e0\u3092\u4f7f\u7528\u3059\u308b\u3053\u3068\u3092\u63a8\u5968\u3057\u3066\u3044\u308b\u304c\u3001\u7cbe\u6db2\u4e2d\u306e\u30a6\u30a4\u30eb\u30b9\u6392\u51fa\u306e\u6f5c\u5728\u7684\u306a\u671f\u9593\u3068\u611f\u67d3\u6027\u306b\u3064\u3044\u3066\u306f\u3001\u3055\u3089\u306a\u308b\u7814\u7a76\u304c\u5fc5\u8981\u3067\u3042\u308b\u3002\u66dd\u9732\u524d\u4e88\u9632\u306b\u304a\u3051\u308b\u30ef\u30af\u30c1\u30f3\u306e\u6f5c\u5728\u7684\u306a\u5f79\u5272\u306b\u3064\u3044\u3066\u3082\u7814\u7a76\u304c\u5fc5\u8981\u3067\u3042\u308b\u3002
\n\u73fe\u5728\u306e\u30a2\u30a6\u30c8\u30d6\u30ec\u30a4\u30af\u306f\u3001\u30b2\u30a4\u307e\u305f\u306f\u30d0\u30a4\u30bb\u30af\u30b7\u30e5\u30a2\u30eb\u306e\u7537\u6027\u3001\u304a\u3088\u3073\u7537\u6027\u3068\u30bb\u30c3\u30af\u30b9\u3092\u3059\u308b\u4ed6\u306e\u7537\u6027\u306b\u4e0d\u5747\u8861\u306b\u5f71\u97ff\u3092\u53ca\u307c\u3057\u3066\u3044\u308b\u304c\u3001\u30b5\u30eb\u75d8\u306f\u300c\u30a2\u30d5\u30ea\u30ab\u306e\u75c5\u6c17\u300d\u3067\u306f\u306a\u304f\u3001\u3082\u306f\u3084\u300c\u30b2\u30a4\u306e\u75c5\u6c17\u300d\u3067\u3082\u306a\u3044\u3002\u8ab0\u306b\u3067\u3082\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u30029\u4eba\u306e\u7570\u6027\u611b\u8005\u306e\u30b5\u30eb\u75d8\u60a3\u8005\u3092\u7279\u5b9a\u3057\u305f\u3002\u7570\u6027\u611b\u8005\u306e\u8a3a\u65ad\u3092\u898b\u9003\u3055\u306a\u3044\u3088\u3046\u306b\u3001\u7279\u306b\u767a\u75b9\u304c\u5168\u8eab\u75c7\u72b6\u3068\u7d44\u307f\u5408\u308f\u3055\u308c\u3066\u3044\u308b\u5834\u5408\u306f\u3001\u7570\u5e38\u306a\u6025\u6027\u767a\u75b9\u3092\u691c\u67fb\u3059\u308b\u969b\u306b\u6ce8\u610f\u3092\u6255\u3046\u3053\u3068\u3092\u304a\u52e7\u3081\u3059\u308b\u3002<\/p>\n

\u4eca\u56de\u306e\u9650\u754c\u3068\u3057\u3066\u306f\u3001\u79c1\u305f\u3061\u306e\u75c7\u4f8b\u30b7\u30ea\u30fc\u30ba\u306f\u3001\u3055\u307e\u3056\u307e\u306a (\u73fe\u5730\u3067\u627f\u8a8d\u3055\u308c\u305f) PCR\u30d7\u30e9\u30c3\u30c8\u30d5\u30a9\u30fc\u30e0\u3067\u611f\u67d3\u304c\u78ba\u8a8d\u3055\u308c\u305f\u89b3\u5bdf\u7684\u306a\u7c21\u6613\u306e\u75c7\u4f8b\u30b7\u30ea\u30fc\u30ba\u3067\u3042\u308b\u3002\u3053\u306e\u75c7\u4f8b\u30b7\u30ea\u30fc\u30ba\u306e\u4eba\u306f\u3001\u533b\u7642\u3092\u5fc5\u8981\u3068\u3059\u308b\u3088\u3046\u306b\u306a\u3063\u305f\u75c7\u72b6\u304c\u3042\u3063\u305f\u3002\u3053\u308c\u306f\u3001\u7121\u75c7\u72b6\u306e\u4eba\u3001\u75c7\u72b6\u304c\u8efd\u5ea6\u306e\u4eba\u3001\u307e\u305f\u306f\u7121\u75c7\u5019\u6027\u306e\u4eba\u3092\u898b\u9003\u3059\u53ef\u80fd\u6027\u304c\u3042\u308b\u3053\u3068\u3092\u610f\u5473\u3059\u308b\u3002\u66b4\u9732\u524d\u306eHIV\u4e88\u9632\u3092\u53d7\u3051\u3066\u3044\u308b\u4eba\u3068\u30bb\u30af\u30b7\u30e5\u30a2\u30eb\u30d8\u30eb\u30b9\u306b\u95a2\u3059\u308b\u533b\u7642\u6a5f\u95a2\u3001\u304a\u3088\u3073HIV \u611f\u67d3\u8005\u3068\u533b\u7642\u6a5f\u95a2\u306e\u9593\u306e\u95a2\u4fc2\u6027\u3084\u8ddd\u96e2\u611f\u306f\u3001\u7279\u306b\u3053\u308c\u3089\u306e\u30b0\u30eb\u30fc\u30d7\u3067\u65e9\u671f\u306b\u30b1\u30a2\u3092\u6c42\u3081\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3053\u3068\u3092\u8003\u3048\u308b\u3068\u3001\u7d39\u4ecb\u30d0\u30a4\u30a2\u30b9\u306b\u3064\u306a\u304c\u3063\u305f\u53ef\u80fd\u6027\u304c\u3042\u308b\u3002\u4ed6\u306e\u96c6\u56e3\u3078\u306e\u62e1\u6563\u304c\u4e88\u60f3\u3055\u308c\u3001\u8b66\u6212\u304c\u5fc5\u8981\u3067\u3042\u308b\u3002\u75c7\u72b6\u306f\u767a\u75c7\u6642\u304b\u3089\u8a18\u9332\u3055\u308c\u3066\u3044\u308b\u305f\u3081\u3001\u521d\u671f\u306e\u75c7\u72b6\u306f\u904e\u5c11\u5831\u544a\u3055\u308c\u3066\u3044\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3002
\n\u30a6\u30a4\u30eb\u30b9\u306b\u306f\u56fd\u5883\u304c\u306a\u3044\u305f\u3081\u3001\u77e5\u8b58\u306e\u30ae\u30e3\u30c3\u30d7\u3092\u57cb\u3081\u3001\u6d41\u884c\u3092\u5c01\u3058\u8fbc\u3081\u308b\u305f\u3081\u306b\u3001\u4e16\u754c\u306f\u56e3\u7d50\u3057\u3066\u8fc5\u901f\u306b\u52d5\u304f\u5fc5\u8981\u304c\u3042\u308b\u3002\u5e83\u304f\u5229\u7528\u53ef\u80fd\u306a\u6cbb\u7642\u6cd5\u3084\u4e88\u9632\u6cd5\u304c\u306a\u3044\u5834\u5408\u3001\u5c01\u3058\u8fbc\u3081\u306b\u306f\u8fc5\u901f\u306a\u75c7\u4f8b\u306e\u7279\u5b9a\u304c\u4e0d\u53ef\u6b20\u3067\u3042\u308b\u3002\u81e8\u5e8a\u533b\u5b66\u3067\u306f\u3088\u304f\u3042\u308b\u3053\u3068\u3060\u304c\u3001\u75c5\u6c17\u304c\u3069\u306e\u3088\u3046\u306b\u73fe\u308c\u308b\u304b\u306b\u306f\u591a\u69d8\u6027\u304c\u3042\u308a\u3001\u30b5\u30eb\u75d8\u3082\u4f8b\u5916\u3067\u306f\u306a\u3044\u3002<\/p>\n

Conclusion
\n\u3053\u306e\u75c7\u4f8b\u30b7\u30ea\u30fc\u30ba\u3067\u306f\u3001\u30b5\u30eb\u75d8\u306f\u3055\u307e\u3056\u307e\u306a\u76ae\u819a\u79d1\u5b66\u7684\u304a\u3088\u3073\u5168\u8eab\u7684\u306a\u81e8\u5e8a\u6240\u898b\u3092\u793a\u3057\u3066\u3044\u308b\u3002\u30b5\u30eb\u75d8\u304c\u4f1d\u7d71\u7684\u306b\u98a8\u571f\u75c5\u3067\u3042\u3063\u305f\u5730\u57df\u4ee5\u5916\u3067\u540c\u6642\u306b\u75c7\u4f8b\u304c\u7279\u5b9a\u3055\u308c\u305f\u3053\u3068\u306f\u3001\u3055\u3089\u306a\u308b\u5730\u57df\u3067\u306e\u611f\u67d3\u62e1\u5927\u3092\u5c01\u3058\u8fbc\u3081\u308b\u305f\u3081\u306b\u75c7\u4f8b\u306e\u8fc5\u901f\u306a\u7279\u5b9a\u3068\u8a3a\u65ad\u306e\u5fc5\u8981\u6027\u3092\u6d6e\u304d\u5f6b\u308a\u306b\u3057\u3066\u3044\u308b\u3002<\/p>\n

\"\"<\/a><\/p>\n

\u3010\u958b\u50ac\u65e5\u30112022\u5e748\u670810\u65e5\uff08\u6c34\uff09<\/p>\n","protected":false},"excerpt":{"rendered":"

\uff0d\u6587\u732e\u540d\uff0d John P. Thornhill. et al. Monkeypox Virus Infection in Humans across 16 Countries \u2014 April\u2013June 2022. NEJ … \u7d9a\u304d\u3092\u8aad\u3080 16\u30ab\u56fd\u306b\u304a\u3051\u308b\u30d2\u30c8\u306e\u30b5\u30eb\u75d8\u30a6\u30a4\u30eb\u30b9\u611f\u67d3<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1,17],"tags":[],"class_list":["post-2363","post","type-post","status-publish","format-standard","hentry","category-1","category-17"],"_links":{"self":[{"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/posts\/2363","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2363"}],"version-history":[{"count":1,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/posts\/2363\/revisions"}],"predecessor-version":[{"id":2365,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/posts\/2363\/revisions\/2365"}],"wp:attachment":[{"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2363"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=2363"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=2363"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}