{"id":2713,"date":"2024-09-04T12:57:56","date_gmt":"2024-09-04T03:57:56","guid":{"rendered":"https:\/\/www.hcfm.jp\/journal\/?p=2713"},"modified":"2024-09-04T13:03:02","modified_gmt":"2024-09-04T04:03:02","slug":"%e3%81%8c%e3%82%93%e6%82%a3%e8%80%85%e3%81%ae%e9%a3%9f%e6%ac%b2%e4%b8%8d%e6%8c%af%e3%81%ab%e5%af%be%e3%81%99%e3%82%8b%e3%83%9f%e3%83%ab%e3%82%bf%e3%82%b6%e3%83%94%e3%83%b3%e3%81%ae%e9%81%a9%e5%bf%9c","status":"publish","type":"post","link":"https:\/\/www.hcfm.jp\/journal\/?p=2713","title":{"rendered":"\u975e\u5c0f\u7d30\u80de\u6027\u80ba\u304c\u3093\u60a3\u8005\u306e\u98df\u6b32\u4e0d\u632f\u306b\u304a\u3051\u308b\u30df\u30eb\u30bf\u30b6\u30d4\u30f3\u306e\u52b9\u679c"},"content":{"rendered":"

\u203b\u3053\u306e\u6642\u671f\u306eUpToDate\u306b\u3042\u308b\u201dWhat\u2019s new in family medicine\u201d\u306eTopic\u3067\u53c2\u8003\u306b\u3055\u308c\u3066\u3044\u308b\u6587\u732e\u3067\u3059\u3002
\n-\u6587\u732e\u540d-
\nArrieta O, C\u00e1rdenas-Fern\u00e1ndez D, Rodriguez-Mayoral O, et al. Mirtazapine as Appetite Stimulant in Patients With Non-Small Cell Lung Cancer and Anorexia: A Randomized Clinical Trial. JAMA Oncol. 2024;10(3):305-314.<\/p>\n

-\u8981\u7d04-
\n\u30fb\u30e1\u30ad\u30b7\u30b3\u306e3\u6b21\u304c\u3093\u30bb\u30f3\u30bf\u30fc\u3067\u306e\u30e9\u30f3\u30c0\u30e0\u5316\u6bd4\u8f03\u8a66\u9a13
\n\u30fb\u304c\u3093\u6027\u98df\u6b32\u4e0d\u632f\u306e\u6a19\u6e96\u6cbb\u7642\u306f\u306a\u304f\u3001\u30df\u30eb\u30bf\u30b6\u30d4\u30f3\u306f\u4e00\u3064\u306e\u9078\u629e\u80a2\u3068\u3057\u3066\u793a\u5506\u3055\u308c\u3066\u3044\u308b\u3002
\n\u30fb\u5148\u884c\u8ad6\u6587\u3067\u306f\u98df\u6b32\u3092\u8a55\u4fa1\u3055\u308c\u3066\u3044\u305f\u304c\u3001\u4eca\u56de\u306f\u6442\u53d6\u30a8\u30cd\u30eb\u30ae\u30fc\u53ca\u3073\u30b5\u30eb\u30b3\u30da\u30cb\u30a2\u306e\u5272\u5408\u3082\u8a55\u4fa1\u3057\u305f
\n\u30fb\u5bfe\u8c61\u8005\u306f\u3001\u9032\u884c\u3057\u305fNSCLC\u3067\u764c\u6cbb\u7642\u85ac\u3092\u4f7f\u7528\u3001Anorexia Cachexia Scale\uff08ACS\uff09\u30b9\u30b3\u30a2\u304c32\u4ee5\u4e0b\u306e\u60a3\u8005
\n\u30fb\u30d7\u30e9\u30bb\u30dcvs\u30df\u30eb\u30bf\u30b6\u30d4\u30f3\u3002\u30df\u30eb\u30bf\u30b6\u30d4\u30f3\u7fa4\u306f15\u65e5\u959315mg\u6295\u4e0e\u3057\u305f\u306e\u3061\u300130mg\u306b\u5897\u91cf\u3057\u305f\u3002\u4e21\u7fa4\u3068\u3082\u6804\u990a\u6307\u5c0e\u3092\u884c\u3063\u305f
\n\u30fb\u8ffd\u8de1\u671f\u9593\u306f8\u9031\u9593\u3067\u30014\u9031\u76ee\u30688\u9031\u76ee\u306b\u8a55\u4fa1\u3092\u884c\u3063\u305f\u3002\u8a55\u4fa1\u306fanorexia cachexia scale\u3068\u30a8\u30cd\u30eb\u30ae\u30fc\u6442\u53d6\u91cf<\/p>\n

\u30fb2018\u5e748\u6708\u304b\u30892022\u5e745\u6708\u306b134\u4eba\u3092\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u3057\u3001\u6761\u4ef6\u3092\u6e80\u305f\u3057\u305f86\u4f8b\u3092\u30df\u30eb\u30bf\u30b6\u30d4\u30f3\u7fa4\u3068\u30d7\u30e9\u30bb\u30dc\u7fa4\u306b\u30e9\u30f3\u30c0\u30e0\u306b\u5272\u308a\u4ed8\u3051\u3002
\n\"\"<\/a>\"\"<\/a>\u30fb\u98df\u6b32\u30b9\u30b3\u30a2\u306f\u30014\u9031\u76ee\u30688\u9031\u76ee\u306b\u4e21\u7fa4\u3067\u6709\u610f\u306b\u5897\u52a0\u3057\u3001 \u4e21\u7fa4\u9593\u306b\u6709\u610f\u5dee\u306f\u8a8d\u3081\u3089\u308c\u306a\u304b\u3063\u305f\u3002
\n\u30fb4\u9031\u5f8c\u3001\u30df\u30eb\u30bf\u30b6\u30d4\u30f3\u306f\u30bf\u30f3\u30d1\u30af\u8cea\uff0822.5g\uff1b95\uff05CI\u300111.5-33.4\uff1bP = 0.001\uff09\u3001\u70ad\u6c34\u5316\u7269\uff0843.4g\uff1b95\uff05CI\u300113.1-73.8\uff1bP = 0.006\uff09\u3001\u8102\u80aa\uff0813.2g\uff1b95\uff05CI\u30016.0-20.4\uff1bP = 0.006\uff09\u3092\u542b\u3080\u30a8\u30cd\u30eb\u30ae\u30fc\u6442\u53d6\u91cf\uff08379.3kcal\uff1b95\uff05CI\u30011382.6-576.1\uff1bP < 0.001\uff09\u3092\u6709\u610f\u306b\u5897\u52a0\u3055\u305b\u305f\u3002\u8102\u80aa\u6442\u53d6\u91cf\u306f8\u9031\u5f8c\u3001\u30df\u30eb\u30bf\u30b6\u30d4\u30f3\u7fa4\u306e\u60a3\u8005\u3067\u6709\u610f\u306b\u591a\u304b\u3063\u305f\uff0814.5g vs 0.7g\uff1bP=0.02\uff09\u3002\u30df\u30eb\u30bf\u30b6\u30d4\u30f3\u7fa4\u3067\u306f\u30018\u9031\u5f8c\u306b\u30b5\u30eb\u30b3\u30da\u30cb\u30a2\u3092\u793a\u3059\u60a3\u8005\u306e\u5272\u5408\u304c\u6709\u610f\u306b\u6e1b\u5c11\u3057\u305f\uff0882.8\uff05 vs 57.1\uff05\u3001P = 0.03\uff09\u3002\n\"\"<\/a>\"\"<\/a>\"\"<\/a>\"\"<\/a>\u30fb\u5bfe\u8c61\u8005\u306f\u3046\u3064\u75c5\u3068\u8a3a\u65ad\u3055\u308c\u306a\u3044\u4eba\u3067\u3042\u3063\u305f\u304c\u3001\u6291\u3046\u3064\u3092\u6e2c\u308bHADS-\u30b9\u30b3\u30a2\u306f\u30df\u30eb\u30bf\u30b6\u30d4\u30f3\u7fa4\u3067\u6709\u610f\u306a\u6539\u5584\u3092\u8a8d\u3081\u305f
\n\u30fb\u60aa\u5922\u304c\u4e0a\u6607\u3057\u305f\u3001\u75b2\u52b4\u306f\u6539\u5584\u3000\u50be\u7720\u306f\u306a\u304b\u3063\u305f<\/p>\n

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\n\u30fb\u3053\u308c\u307e\u3067\u306e\u7814\u7a76\u306f15mg\u6295\u4e0e\u306b\u7559\u307e\u308a\u3001\u98df\u6b32\u306e\u307f\u3092\u8a55\u4fa1\u3057\u3066\u3044\u305f
\n\u30fb\u30df\u30eb\u30bf\u30b6\u30d4\u30f330mg\u306b\u5897\u91cf\u3057\u305f\u304c\u3001\u3046\u3064\u75c5\u306e\u30b9\u30b3\u30a2\u6539\u5584\u3082\u3042\u308a\u3001\u5b89\u5168\u6027\u306b\u554f\u984c\u306f\u306a\u304b\u3063\u305f\u3068\u8003\u3048\u308b\u3002\u50be\u7720\u306a\u3069\u306e\u6709\u5bb3\u4e8b\u8c61\u3082\u51fa\u73fe\u3057\u306a\u304b\u3063\u305f\u3002
\n\u30fb\u4eca\u56de\u306f\u4f53\u91cd\u306b\u5dee\u304c\u51fa\u306a\u304b\u3063\u305f\u3002\u5bfe\u8c61\u60a3\u8005\u306f\u300c\u98df\u6b32\u4e0d\u632f\u304c\u3042\u308b\u304b\u300d\u3067\u3042\u308a\u300c\u4f53\u91cd\u6e1b\u5c11\u3057\u3066\u3044\u308b\u304b\u3069\u3046\u304b\u300d\u306f\u8003\u616e\u3057\u306a\u304b\u3063\u305f\u3002\u307e\u305f\u30b5\u30f3\u30d7\u30eb\u30b5\u30a4\u30ba\u304c\u5c11\u306a\u304b\u3063\u305f\u3002
\n\u3053\u308c\u3089\u306e\u3053\u3068\u304b\u3089\u4f53\u91cd\u5909\u5316\u306b\u306f\u5dee\u304c\u306a\u304b\u3063\u305f\u306e\u3067\u306f<\/p>\n

\u30fb\u304c\u3093\u306e\u98df\u601d\u4e0d\u632f\u306e\u6a19\u6e96\u6cbb\u7642\u306f\u307e\u3060\u306a\u3044
\n\u4f8b\u3048\u3070\u30aa\u30e9\u30f3\u30b6\u30d4\u30f3\u306e\u4f4e\u5bb9\u91cf\u306e\u5831\u544a\u306f\u3042\u308b\u304c\u3001\u305d\u308c\u3089\u306f\u4f4e\u4f53\u91cd\u60a3\u8005\u3067\u306e\u7814\u7a76\u5831\u544a\u3060\u3063\u305f\u3002\u4eca\u56de\u306f\u6b63\u5e38\u4f53\u91cd\u60a3\u8005\u304c\u5bfe\u8c61\u3067\u3042\u308b\u3002<\/p>\n

\u30ea\u30df\u30c6\u30fc\u30b7\u30e7\u30f3\uff1a
\n\u30fb\u5358\u4e00\u65bd\u8a2d\u3067\u306e\u7814\u7a76
\n\u30fb\u30b5\u30f3\u30d7\u30eb\u306e\u5c11\u306a\u3055
\n\u30fb\u6cbb\u7642\u4e2d\u306e\u60a3\u8005\u3000\u5614\u6c17\u306b\u5bfe\u3057\u3066\u5c11\u91cf\u30b9\u30c6\u30ed\u30a4\u30c9\u304c\u5165\u3063\u3066\u3044\u305f\u30b1\u30fc\u30b9\u3082\u3042\u3063\u305f<\/p>\n

\u3010\u958b\u50ac\u65e5\u30112024\u5e749\u67084\u65e5<\/p>\n","protected":false},"excerpt":{"rendered":"

\u203b\u3053\u306e\u6642\u671f\u306eUpToDate\u306b\u3042\u308b\u201dWhat\u2019s new in family medicine\u201d\u306eTopic\u3067\u53c2\u8003\u306b\u3055\u308c\u3066\u3044\u308b\u6587\u732e\u3067\u3059\u3002 -\u6587\u732e\u540d- Arrieta O, C\u00e1rdenas-Fern\u00e1ndez D, Ro … \u7d9a\u304d\u3092\u8aad\u3080 \u975e\u5c0f\u7d30\u80de\u6027\u80ba\u304c\u3093\u60a3\u8005\u306e\u98df\u6b32\u4e0d\u632f\u306b\u304a\u3051\u308b\u30df\u30eb\u30bf\u30b6\u30d4\u30f3\u306e\u52b9\u679c<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[33,12],"tags":[],"class_list":["post-2713","post","type-post","status-publish","format-standard","hentry","category-whats-new","category-12"],"_links":{"self":[{"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/posts\/2713","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2713"}],"version-history":[{"count":3,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/posts\/2713\/revisions"}],"predecessor-version":[{"id":2722,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/posts\/2713\/revisions\/2722"}],"wp:attachment":[{"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2713"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=2713"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=2713"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}