{"id":2931,"date":"2025-11-05T14:37:05","date_gmt":"2025-11-05T05:37:05","guid":{"rendered":"https:\/\/www.hcfm.jp\/journal\/?p=2931"},"modified":"2025-11-05T14:37:05","modified_gmt":"2025-11-05T05:37:05","slug":"%e5%b8%af%e7%8a%b6%e7%96%b1%e7%96%b9%e3%81%8a%e3%82%88%e3%81%b3rs%e3%82%a6%e3%82%a4%e3%83%ab%e3%82%b9%e6%84%9f%e6%9f%93%e7%97%87%e3%81%ab%e5%af%be%e3%81%99%e3%82%8bas01%e3%82%a2%e3%82%b8%e3%83%a5","status":"publish","type":"post","link":"https:\/\/www.hcfm.jp\/journal\/?p=2931","title":{"rendered":"\u5e2f\u72b6\u75b1\u75b9\u304a\u3088\u3073RS\u30a6\u30a4\u30eb\u30b9\u611f\u67d3\u75c7\u306b\u5bfe\u3059\u308bAS01\u30a2\u30b8\u30e5\u30d0\u30f3\u30c8\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u306b\u3088\u308b\u8a8d\u77e5\u75c7\u30ea\u30b9\u30af\u306e\u4f4e\u6e1b"},"content":{"rendered":"<p>\uff70\u6587\u732e\u540d\uff70<br \/>\nMaxime Taquet, John A Todd, Paul J Harrison. Lower risk of dementia with AS01-adjuvanted vaccination against shingles and respiratory syncytial virus infections. NPJ Vaccines<br \/>\n. 2025 Jun 25;10(1):130<\/p>\n<p>\u2010\u8981\u7d04-<br \/>\nIntroduction\uff08\u306f\u3058\u3081\u306b\uff09<br \/>\n\u3053\u308c\u307e\u3067\u306b\u5206\u304b\u3063\u3066\u3044\u308b\u3053\u3068\uff1a \u5e2f\u72b6\u75b1\u75b9\u306e\u4e88\u9632\u63a5\u7a2e\u3001\u7279\u306bAS01\u30a2\u30b8\u30e5\u30d0\u30f3\u30c8\u3092\u542b\u3080\u7d44\u63db\u3048\u30ef\u30af\u30c1\u30f3\uff08Shingrix\uff09\u304c\u3001\u8a8d\u77e5\u75c7\u306e\u767a\u75c7\u30ea\u30b9\u30af\u4f4e\u4e0b\u3068\u95a2\u9023\u3057\u3066\u3044\u308b\u3068\u3044\u3046\u8a3c\u62e0\u304c\u84c4\u7a4d\u3057\u3066\u3044\u307e\u3059 \u3002\u8457\u8005\u3089\u306e\u5148\u884c\u7814\u7a76\u3067\u3082\u3001AS01\u30a2\u30b8\u30e5\u30d0\u30f3\u30c8\u3092\u542b\u3080Shingrix\u306f\u3001\u30a2\u30b8\u30e5\u30d0\u30f3\u30c8\u3092\u542b\u307e\u306a\u3044\u5f93\u6765\u306e\u751f\u30ef\u30af\u30c1\u30f3\uff08Zostavax\uff09\u3088\u308a\u3082\u3001\u8a8d\u77e5\u75c7\u30ea\u30b9\u30af\u306e\u4f4e\u4e0b\u52b9\u679c\u304c\u9ad8\u3044\u3053\u3068\u304c\u793a\u5506\u3055\u308c\u3066\u3044\u307e\u3059 \u3002<\/p>\n<p>\u5206\u304b\u3063\u3066\u3044\u306a\u3044\u3053\u3068\uff1a AS01\u30a2\u30b8\u30e5\u30d0\u30f3\u30c8\u6dfb\u52a0\u30ef\u30af\u30c1\u30f3\u304c\u306a\u305c\u8a8d\u77e5\u75c7\u3092\u4e88\u9632\u3059\u308b\u306e\u304b\u3001\u305d\u306e\u30e1\u30ab\u30cb\u30ba\u30e0\u306f\u4e0d\u660e\u3067\u3059 \u3002\u4e3b\u306a\u4eee\u8aac\u3068\u3057\u3066\u3001\u4ee5\u4e0b\u306e2\u3064\u304c\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059 \u3002<\/p>\n<p>\u2460\u611f\u67d3\u4e88\u9632\u4eee\u8aac\uff1a<br \/>\n\u5e2f\u72b6\u75b1\u75b9\u30a6\u30a4\u30eb\u30b9\u81ea\u4f53\u304c\u8a8d\u77e5\u75c7\u30ea\u30b9\u30af\u3092\u9ad8\u3081\u308b\u305f\u3081\u3001\u30ef\u30af\u30c1\u30f3\u306e\u9ad8\u3044\u6709\u52b9\u6027\uff08AS01\u306b\u3088\u308b\uff09\u304c\u611f\u67d3\u3092\u5f37\u529b\u306b\u9632\u304e\u3001\u7d50\u679c\u3068\u3057\u3066\u8a8d\u77e5\u75c7\u3092\u4e88\u9632\u3059\u308b\u3002<\/p>\n<p>\u2461\u30a2\u30b8\u30e5\u30d0\u30f3\u30c8\u76f4\u63a5\u52b9\u679c\u4eee\u8aac\uff1a<br \/>\nAS01\u30a2\u30b8\u30e5\u30d0\u30f3\u30c8\u81ea\u4f53\u304c\u3001\u514d\u75ab\u7cfb\u3092\u4ecb\u3057\u3066\uff08\u30de\u30a6\u30b9\u30e2\u30c7\u30eb\u3067\u793a\u5506\u3055\u308c\u3066\u3044\u308b\u3088\u3046\u306b\uff09\u8a8d\u77e5\u75c7\u306b\u5bfe\u3057\u3066\u76f4\u63a5\u7684\u306a\u4fdd\u8b77\u4f5c\u7528\u3092\u6301\u3064\u3002<\/p>\n<p>\u672c\u7814\u7a76\u306e\u76ee\u7684\uff1a \u3053\u308c\u3089\u306e\u4eee\u8aac\u3092\u691c\u8a3c\u3059\u308b\u305f\u3081\u3001\u672c\u7814\u7a76\u3067\u306f\u3001\u5e2f\u72b6\u75b1\u75b9\u30ef\u30af\u30c1\u30f3\uff08Shingrix\uff09\u3068\u540c\u3058AS01\u30a2\u30b8\u30e5\u30d0\u30f3\u30c8\u3092\u542b\u3080RSV\uff08\u547c\u5438\u5668\u5408\u80de\u4f53\u30a6\u30a4\u30eb\u30b9\uff09\u30ef\u30af\u30c1\u30f3\uff08Arexvy\uff09\u306b\u7740\u76ee\u3057\u307e\u3057\u305f \u3002 \u3082\u3057\u300c\u30a2\u30b8\u30e5\u30d0\u30f3\u30c8\u76f4\u63a5\u52b9\u679c\u4eee\u8aac\u300d\u304c\u6b63\u3057\u3051\u308c\u3070\u3001RSV\u30ef\u30af\u30c1\u30f3\u3082\u5e2f\u72b6\u75b1\u75b9\u30ef\u30af\u30c1\u30f3\u3068\u540c\u69d8\u306b\u8a8d\u77e5\u75c7\u30ea\u30b9\u30af\u3092\u4f4e\u4e0b\u3055\u305b\u308b\u306f\u305a\u3067\u3059\u3002\u305d\u3053\u3067\u8457\u8005\u3089\u306f\u3001\u3053\u308c\u30892\u3064\u306eAS01\u542b\u6709\u30ef\u30af\u30c1\u30f3\u3068\u3001\u5bfe\u7167\u3068\u3057\u3066\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u30ef\u30af\u30c1\u30f3\u3092\u6bd4\u8f03\u3057\u3001\u63a5\u7a2e\u5f8c18\u30f6\u6708\u9593\u306e\u8a8d\u77e5\u75c7\u8a3a\u65ad\u30ea\u30b9\u30af\u3092\u8a55\u4fa1\u3057\u307e\u3057\u305f \u3002<\/p>\n<p>Method\uff08\u65b9\u6cd5\uff09<br \/>\n\u7814\u7a76\u30c7\u30b6\u30a4\u30f3\uff1a\u7c73\u56fd\u306e\u96fb\u5b50\u5065\u5eb7\u8a18\u9332\uff08EHR\uff09\u30c7\u30fc\u30bf\u30d9\u30fc\u30b9\u300cTriNetX\u300d\u3092\u7528\u3044\u305f\u3001\u5f8c\u308d\u5411\u304d\u30b3\u30db\u30fc\u30c8\u7814\u7a76\u3067\u3059 \u3002<\/p>\n<p>\u5bfe\u8c61\u30b3\u30db\u30fc\u30c8\uff1a2023\u5e745\u67081\u65e5\u4ee5\u964d\u306b\u30ef\u30af\u30c1\u30f3\u3092\u63a5\u7a2e\u3057\u305f60\u6b73\u4ee5\u4e0a\u306e\u4eba\u3005\u3092\u5bfe\u8c61\u3068\u3057\u307e\u3057\u305f\u3002\u4ee5\u4e0b\u306e3\u3064\u306e\u66dd\u9732\u7fa4\u3092\u8a2d\u5b9a\u3057\u307e\u3057\u305f \u3002<\/p>\n<p>\u2460AS01 RSV\u30ef\u30af\u30c1\u30f3\u306e\u307f \u63a5\u7a2e\u7fa4 (N=35,938)<br \/>\n\u2461AS01\u5e2f\u72b6\u75b1\u75b9\u30ef\u30af\u30c1\u30f3\u306e\u307f \u63a5\u7a2e\u7fa4 (N=103,798)<br \/>\n\u2462\u4e21\u65b9 \u63a5\u7a2e\u7fa4 (N=78,658) <\/p>\n<p>\u6bd4\u8f03\u5bfe\u7167\u3068\u30de\u30c3\u30c1\u30f3\u30b0\uff1a\u6bd4\u8f03\u5bfe\u7167\u3068\u3057\u3066\u3001AS01\u3092\u542b\u307e\u306a\u3044\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u7fa4\u3092\u7528\u3044\u307e\u3057\u305f \u3002 \u5e74\u9f62\u3001\u6027\u5225\u3001\u4eba\u7a2e\u3001\u4f75\u5b58\u75be\u60a3\uff08\u9ad8\u8840\u5727\u3001\u7cd6\u5c3f\u75c5\u3001\u547c\u5438\u5668\u75be\u60a3\u306a\u3069\uff09\u3092\u542b\u308066\u306e\u5171\u5909\u91cf\u3092\u7528\u3044\u3066\u3001\u66dd\u9732\u7fa4\u3068\u5bfe\u7167\u7fa4\u30921:1\u306e\u50be\u5411\u30b9\u30b3\u30a2\u30de\u30c3\u30c1\u30f3\u30b0\uff08Propensity score 1:1 matching\uff09\u3067\u8abf\u6574\u3057\u307e\u3057\u305f\u3002\u30de\u30c3\u30c1\u30f3\u30b0\u5f8c\u3001\u3059\u3079\u3066\u306e\u5171\u5909\u91cf\u306b\u304a\u3044\u3066\u7fa4\u9593\u306e\u30d0\u30e9\u30f3\u30b9\u306f\u826f\u597d\u3067\u3057\u305f\uff08\u5168SMD < 0.1\uff09\u3002\n\n\u30a2\u30a6\u30c8\u30ab\u30e0\u3068\u7d71\u8a08\u89e3\u6790\uff1a \u4e3b\u8981\u30a2\u30a6\u30c8\u30ab\u30e0\u306f\u3001\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u5f8c3\u30f6\u6708\u304b\u308918\u30f6\u6708\u307e\u3067\u306e\u300c\u521d\u56de\u8a8d\u77e5\u75c7\u8a3a\u65ad\u300d\uff08\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u3001\u8840\u7ba1\u6027\u8a8d\u77e5\u75c7\u306a\u3069\u3092\u542b\u3080\uff09\u3068\u3057\u307e\u3057\u305f \u3002 \u7d71\u8a08\u89e3\u6790\u3067\u306f\u3001\u6bd4\u4f8b\u30cf\u30b6\u30fc\u30c9\u6027\u306e\u4eee\u5b9a\u304c\u6e80\u305f\u3055\u308c\u306a\u304b\u3063\u305f\u305f\u3081\u3001Cox\u30e2\u30c7\u30eb\u306e\u4ee3\u308f\u308a\u306b\u5236\u9650\u4ed8\u304d\u5e73\u5747\u6642\u9593\u55aa\u5931\uff08RMTL; restricted mean time lost\uff09\u3092\u7528\u3044\u3066\u7fa4\u9593\u6bd4\u8f03\u3092\u884c\u3044\u307e\u3057\u305f \u3002RMTL\u6bd4\u304c1\u672a\u6e80\u306e\u5834\u5408\u3001\u30a2\u30a6\u30c8\u30ab\u30e0\uff08\u8a8d\u77e5\u75c7\u8a3a\u65ad\uff09\u3092\u7d4c\u9a13\u305b\u305a\u306b\u904e\u3054\u3057\u305f\u6642\u9593\u304c\u3088\u308a\u9577\u3044\u3053\u3068\u3001\u3059\u306a\u308f\u3061\u30ea\u30b9\u30af\u304c\u4f4e\u3044\u3053\u3068\u3092\u793a\u3057\u307e\u3059 \u3002\n\nResults\uff08\u7d50\u679c\uff09\nAS01\u30ef\u30af\u30c1\u30f3 vs \u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u30ef\u30af\u30c1\u30f3\uff08\u5bfe\u7167\u7fa4\uff09\uff1aFig. 2\u306b\u793a\u3059\u901a\u308a\u3001\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u30ef\u30af\u30c1\u30f3\u7fa4\u3068\u6bd4\u8f03\u3057\u3066\u3001AS01\u30ef\u30af\u30c1\u30f3\u3092\u63a5\u7a2e\u3057\u305f\u7fa4\u306f\u3059\u3079\u3066\u300118\u30f6\u6708\u9593\u306e\u8a8d\u77e5\u75c7\u8a3a\u65ad\u30ea\u30b9\u30af\u304c\u6709\u610f\u306b\u4f4e\u4e0b\u3057\u307e\u3057\u305f \u3002\n<a href=\"https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2025\/11\/841adf1792543ee0d334e9605fbdc2ad-1.png\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2025\/11\/841adf1792543ee0d334e9605fbdc2ad-1.png\" alt=\"\" width=\"1636\" height=\"1049\" class=\"alignnone size-full wp-image-2934\" srcset=\"https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2025\/11\/841adf1792543ee0d334e9605fbdc2ad-1.png 1636w, https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2025\/11\/841adf1792543ee0d334e9605fbdc2ad-1-300x192.png 300w, https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2025\/11\/841adf1792543ee0d334e9605fbdc2ad-1-1024x657.png 1024w, https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2025\/11\/841adf1792543ee0d334e9605fbdc2ad-1-768x492.png 768w, https:\/\/www.hcfm.jp\/journal\/wp-content\/uploads\/2025\/11\/841adf1792543ee0d334e9605fbdc2ad-1-1536x985.png 1536w\" sizes=\"auto, (max-width: 1636px) 100vw, 1636px\" \/><\/a><\/p>\n<p>\u30fbRSV\u30ef\u30af\u30c1\u30f3\u306e\u307f\u7fa4\uff08RMTL\u6bd4 0.71 \/ \u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u7fa4\u6bd429%\u6539\u5584\uff09<br \/>\n\u5bfe\u7167\u7fa4\u3088\u308a\u5e73\u5747\u3057\u3066 87\u65e5\u9593\u3001\u8a8d\u77e5\u75c7\u3068\u8a3a\u65ad\u3055\u308c\u305a\u306b\u904e\u3054\u3059\u6642\u9593\u304c\u9577\u304b\u3063\u305f \u3002<\/p>\n<p>\u30fb\u5e2f\u72b6\u75b1\u75b9\u30ef\u30af\u30c1\u30f3\u306e\u307f\u7fa4\uff08RMTL\u6bd4 0.82 \/ \u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u7fa4\u6bd418%\u6539\u5584\uff09<br \/>\n\u5bfe\u7167\u7fa4\u3088\u308a\u5e73\u5747\u3057\u3066 53\u65e5\u9593\u3001\u8a8d\u77e5\u75c7\u3068\u8a3a\u65ad\u3055\u308c\u305a\u306b\u904e\u3054\u3059\u6642\u9593\u304c\u9577\u304b\u3063\u305f \u3002<\/p>\n<p>\u30fb\u4e21\u65b9\u63a5\u7a2e\u7fa4\uff08RMTL\u6bd4 0.63 \/ \u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u7fa4\u6bd437%\u6539\u5584\uff09<br \/>\n\u5bfe\u7167\u7fa4\u3088\u308a\u5e73\u5747\u3057\u3066 113\u65e5\u9593\u3001\u8a8d\u77e5\u75c7\u3068\u8a3a\u65ad\u3055\u308c\u305a\u306b\u904e\u3054\u3059\u6642\u9593\u304c\u9577\u304b\u3063\u305f \u3002<\/p>\n<p>AS01\u30ef\u30af\u30c1\u30f3\u9593\u306e\u6bd4\u8f03\uff1aRSV\u30ef\u30af\u30c1\u30f3\u306e\u307f\u7fa4\u3068\u5e2f\u72b6\u75b1\u75b9\u30ef\u30af\u30c1\u30f3\u306e\u307f\u7fa4\u306e\u9593\u3067\u3001\u8a8d\u77e5\u75c7\u30ea\u30b9\u30af\u306b\u6709\u610f\u306a\u5dee\u306f\u898b\u3089\u308c\u307e\u305b\u3093\u3067\u3057\u305f\uff08RMTL\u6bd41.15, P=0.077\uff09\u3002\u307e\u305f\u3001\u4e21\u65b9\u306e\u30ef\u30af\u30c1\u30f3\u3092\u63a5\u7a2e\u3057\u305f\u7fa4\u306f\u3001\u3069\u3061\u3089\u304b\u4e00\u65b9\u306e\u30ef\u30af\u30c1\u30f3\u306e\u307f\u3092\u63a5\u7a2e\u3057\u305f\u7fa4\uff08RSV\u306e\u307f\u3001\u307e\u305f\u306f\u5e2f\u72b6\u75b1\u75b9\u306e\u307f\uff09\u3068\u6bd4\u8f03\u3057\u3066\u3082\u3001\u30ea\u30b9\u30af\u306b\u6709\u610f\u306a\u5dee\u306f\u3042\u308a\u307e\u305b\u3093\u3067\u3057\u305f \u3002<\/p>\n<p>Discussion\uff08\u8003\u5bdf\uff09<br \/>\n\u7d50\u679c\u306e\u89e3\u91c8\uff1a\u672c\u7814\u7a76\u306b\u3088\u308a\u3001AS01\u30a2\u30b8\u30e5\u30d0\u30f3\u30c8\u3092\u542b\u3080\u5e2f\u72b6\u75b1\u75b9\u30ef\u30af\u30c1\u30f3\u3068RSV\u30ef\u30af\u30c1\u30f3\u306f\u3001\u3069\u3061\u3089\u3082\u8a8d\u77e5\u75c7\u30ea\u30b9\u30af\u306e\u4f4e\u4e0b\u3068\u95a2\u9023\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u307e\u3057\u305f \u3002<\/p>\n<p>\u91cd\u8981\u306a\u70b9\u306f\u3001\u4e21\u65b9\u306e\u30ef\u30af\u30c1\u30f3\u3092\u63a5\u7a2e\u3057\u3066\u3082\u3001\u7247\u65b9\u3060\u3051\u3092\u63a5\u7a2e\u3057\u305f\u5834\u5408\u3068\u6bd4\u3079\u3066\u8ffd\u52a0\u306e\u4fdd\u8b77\u52b9\u679c\uff08\u76f8\u52a0\u52b9\u679c\uff09\u304c\u898b\u3089\u308c\u306a\u304b\u3063\u305f\u3053\u3068\u3067\u3059\u3002\u3082\u3057\u3001\u305d\u308c\u305e\u308c\u306e\u30ef\u30af\u30c1\u30f3\u304c\u300cRSV\u611f\u67d3\u4e88\u9632\u300d\u3068\u300c\u5e2f\u72b6\u75b1\u75b9\u611f\u67d3\u4e88\u9632\u300d\u3068\u3044\u3046\u5225\u3005\u306e\u30e1\u30ab\u30cb\u30ba\u30e0\u3067\u8a8d\u77e5\u75c7\u3092\u9632\u3044\u3067\u3044\u308b\u306e\u3067\u3042\u308c\u3070\u3001\u4e21\u65b9\u63a5\u7a2e\u3059\u308c\u3070\u52b9\u679c\u306f\u4e0a\u4e57\u305b\u3055\u308c\u308b\u306f\u305a\u3067\u3059\u3002<\/p>\n<p>\u3053\u306e\u7d50\u679c\uff08\u76f8\u52a0\u52b9\u679c\u306e\u6b20\u5982\uff09\u3068\u3001\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u5f8c\u6bd4\u8f03\u7684\u77ed\u671f\u9593\uff08\u6570\u30f6\u6708\uff09\u3067\u52b9\u679c\u304c\u898b\u3089\u308c\u308b\u3053\u3068 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\/>\nEHR\u30c7\u30fc\u30bf\u56fa\u6709\u306e\u554f\u984c\uff08\u8a3a\u65ad\u306e\u6b63\u78ba\u6027\u3001\u30e9\u30a4\u30d5\u30b9\u30bf\u30a4\u30eb\u8981\u56e0\u306e\u6b20\u5982\u306a\u3069\uff09\u304c\u3042\u308a\u307e\u3059 \u3002<br \/>\n\u89b3\u5bdf\u7814\u7a76\u3067\u3042\u308b\u305f\u3081\u3001\u672a\u77e5\u306e\u4ea4\u7d61\u56e0\u5b50\u306b\u3088\u308b\u30d0\u30a4\u30a2\u30b9\u306e\u53ef\u80fd\u6027\u306f\u6b8b\u308a\u307e\u3059 \u3002<\/p>\n<p>\u6700\u5927\u306e\u9650\u754c\u70b9\u3068\u3057\u3066\u3001EHR\u30c7\u30fc\u30bf\u4e0a\u3001RSV\u30ef\u30af\u30c1\u30f3\u304cAS01\u3092\u542b\u3080\u300cArexvy\u300d\u3068AS01\u3092\u542b\u307e\u306a\u3044\u300cAbrysvo\u300d\u3092\u533a\u5225\u3067\u304d\u3066\u3044\u306a\u3044\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059 \u3002\u8457\u8005\u3089\u306e\u63a8\u5b9a\u3067\u306f\u3001RSV\u30ef\u30af\u30c1\u30f3\u7fa4\u306e\u7d0424%\u304cAS01\u3092\u542b\u307e\u306a\u3044Abrysvo\u3092\u63a5\u7a2e\u3057\u305f\u3068\u898b\u3089\u308c 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Lower risk of dementia with AS01-adjuvanted vaccination aga &hellip; <a href=\"https:\/\/www.hcfm.jp\/journal\/?p=2931\" class=\"more-link\">\u7d9a\u304d\u3092\u8aad\u3080 <span class=\"screen-reader-text\">\u5e2f\u72b6\u75b1\u75b9\u304a\u3088\u3073RS\u30a6\u30a4\u30eb\u30b9\u611f\u67d3\u75c7\u306b\u5bfe\u3059\u308bAS01\u30a2\u30b8\u30e5\u30d0\u30f3\u30c8\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u306b\u3088\u308b\u8a8d\u77e5\u75c7\u30ea\u30b9\u30af\u306e\u4f4e\u6e1b<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[5,23,11],"tags":[],"class_list":["post-2931","post","type-post","status-publish","format-standard","hentry","category-5","category-23","category-11"],"_links":{"self":[{"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/posts\/2931","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2931"}],"version-history":[{"count":3,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/posts\/2931\/revisions"}],"predecessor-version":[{"id":2936,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/posts\/2931\/revisions\/2936"}],"wp:attachment":[{"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2931"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=2931"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=2931"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}