{"id":2977,"date":"2026-02-05T12:46:10","date_gmt":"2026-02-05T03:46:10","guid":{"rendered":"https:\/\/www.hcfm.jp\/journal\/?p=2977"},"modified":"2026-02-05T12:46:10","modified_gmt":"2026-02-05T03:46:10","slug":"%e6%97%a5%e6%9c%ac%e4%ba%ba%e9%ab%98%e9%bd%a2%e8%80%85%e3%81%ab%e5%af%be%e3%81%99%e3%82%8b%e9%ab%98%e7%94%a8%e9%87%8f%e3%82%a4%e3%83%b3%e3%83%95%e3%83%ab%e3%82%a8%e3%83%b3%e3%82%b6%e3%83%af%e3%82%af","status":"publish","type":"post","link":"https:\/\/www.hcfm.jp\/journal\/?p=2977","title":{"rendered":"\u65e5\u672c\u4eba\u9ad8\u9f62\u8005\u306b\u5bfe\u3059\u308b\u9ad8\u7528\u91cf\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u30ef\u30af\u30c1\u30f3\u306e\u6a19\u6e96\u7528\u91cf\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u30ef\u30af\u30c1\u30f3\u3068\u306e\u6bd4\u8f03\u52b9\u679c"},"content":{"rendered":"

-\u6587\u732e\u540d-
\nSuperior immunogenicity of high-dose quadrivalent inactivated influenza vaccine versus Standard-Dose vaccine in Japanese Adults \u226760 years of age: Results from a phase III, randomized clinical trial. Vaccine 41 (2023) 2553\u20132561<\/p>\n

-\u8981\u7d04-
\n\u3010\u80cc\u666f\u3011
\n\u3000\u9ad8\u7528\u91cf\u5206\u5272\u30a6\u30a4\u30eb\u30b9\u578b\u4e0d\u6d3b\u53164\u4fa1\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u30ef\u30af\u30c1\u30f3\uff08IIV4-HD; Sanofi\uff09\u306f\u3001\u8907\u6570\u306e\u56fd\u3067\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u4e88\u9632\u306b\u4f7f\u7528\u3055\u308c\u3066\u3044\u308b\u3002\u672c\u7814\u7a76\u3067\u306f\u3001\u65e5\u672c\u306b\u304a\u3044\u3066\u7b4b\u8089\u5185\u6ce8\u5c04\uff08IM\uff09\u3067\u6295\u4e0e\u3055\u308c\u305fIIV4-HD\u30ef\u30af\u30c1\u30f3\u3068\u3001\u5c40\u6240\u3067\u8a8d\u53ef\u3055\u308c\u305f\u6a19\u6e96\u7528\u91cf\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u30ef\u30af\u30c1\u30f3\uff08IIV4-SD\uff09\u3092\u76ae\u4e0b\u6295\u4e0e\uff08SC\uff09\u3057\u305f\u5834\u5408\u306e\u514d\u75ab\u539f\u6027\u304a\u3088\u3073\u5b89\u5168\u6027\u3092\u6bd4\u8f03\u3057\u305f\u3002<\/p>\n

\u3010\u65b9\u6cd5\u3011
\n\u3000\u672c\u7814\u7a76\u306f\u30012020\u5e74\u304b\u30892021\u5e74\u306e\u5317\u534a\u7403\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u30b7\u30fc\u30ba\u30f3\u4e2d\u306b\u65e5\u672c\u3067\u5b9f\u65bd\u3055\u308c\u305f\u7b2cIII\u76f8\u3001\u30e9\u30f3\u30c0\u30e0\u5316\u3001\u4fee\u6b63\u4e8c\u91cd\u76f2\u691c\u3001\u30a2\u30af\u30c6\u30a3\u30d6\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u3001\u591a\u65bd\u8a2d\u8a66\u9a13\u3067\u3042\u308b\u3002\u53c2\u52a0\u8005\u306f1:1\u306e\u5272\u5408\u3067\u30e9\u30f3\u30c0\u30e0\u306b\u5272\u308a\u4ed8\u3051\u3089\u308c\u3001IIV4-HD\u3092IM\u30671\u56de\u6295\u4e0e\u3059\u308b\u7fa4\u3068\u3001IIV4-SD\u3092SC\u30671\u56de\u6295\u4e0e\u3059\u308b\u7fa4\u306b\u5206\u3051\u3089\u308c\u305f\u3002\u30d8\u30de\u30b0\u30eb\u30c1\u30cb\u30f3\u963b\u5bb3\u6297\u4f53\uff08HAI\uff09\u304a\u3088\u3073\u8840\u6e05\u8ee2\u63db\u7387\u306f\u3001\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3\u304a\u3088\u307328\u65e5\u76ee\u306b\u6e2c\u5b9a\u3055\u308c\u305f\u3002\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u5f8c7\u65e5\u9593\u306e\u967d\u6027\u53cd\u5fdc\u300128\u65e5\u9593\u306e\u975e\u967d\u6027\u6709\u5bb3\u4e8b\u8c61\u3001\u8a66\u9a13\u671f\u9593\u4e2d\u306e\u91cd\u7be4\u306a\u6709\u5bb3\u4e8b\u8c61\u3092\u53ce\u96c6\u3057\u305f\u3002<\/p>\n

\u3010\u7d50\u679c\u3011
\n\u3000\u672c\u7814\u7a76\u306b\u306f60\u6b73\u4ee5\u4e0a\u306e\u6210\u4eba2,100\u540d\u304c\u53c2\u52a0\u3057\u305f\u3002IM\u3067\u6295\u4e0e\u3055\u308c\u305fIIV4-HD\u306f\u3001SC\u3067\u6295\u4e0e\u3055\u308c\u305fIIV4-SD\u3068\u6bd4\u8f03\u3057\u3066\u3001\u3059\u3079\u3066\u306e\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u682a\u306b\u304a\u3044\u3066\u5e7e\u4f55\u5e73\u5747\u6297\u4f53\u4fa1\uff08GMT\uff09\u3067\u8a55\u4fa1\u3055\u308c\u305f\u514d\u75ab\u5fdc\u7b54\u304c\u512a\u308c\u3066\u3044\u305f\u3002\u307e\u305f\u3001\u3059\u3079\u3066\u306e\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u682a\u306b\u304a\u3044\u3066\u3001IIV4-HD\u306e\u8840\u6e05\u8ee2\u63db\u7387\u304cIIV4-SD\u3088\u308a\u3082\u512a\u308c\u3066\u3044\u308b\u3053\u3068\u304c\u78ba\u8a8d\u3055\u308c\u305f\u3002IIV4-HD\u3068IIV4-SD\u306e\u5b89\u5168\u6027\u30d7\u30ed\u30d5\u30a1\u30a4\u30eb\u306f\u985e\u4f3c\u3057\u3066\u304a\u308a\u3001IIV4-HD\u306f\u53c2\u52a0\u8005\u306b\u826f\u597d\u306b\u8010\u5bb9\u3055\u308c\u3001\u5b89\u5168\u6027\u306b\u95a2\u3059\u308b\u61f8\u5ff5\u306f\u8a8d\u3081\u3089\u308c\u306a\u304b\u3063\u305f\u3002<\/p>\n

\u3010\u7d50\u8ad6\u3011
\n\u3000IIV4-HD\u306f\u3001\u514d\u75ab\u539f\u6027\u304cIIV4-SD\u3088\u308a\u3082\u512a\u308c\u3066\u304a\u308a\u3001\u65e5\u672c\u306e60\u6b73\u4ee5\u4e0a\u306e\u6210\u4eba\u306b\u304a\u3044\u3066\u826f\u597d\u306b\u8010\u5bb9\u3055\u308c\u305f\u3002\u8907\u6570\u306e\u30e9\u30f3\u30c0\u30e0\u5316\u6bd4\u8f03\u8a66\u9a13\u304a\u3088\u3073\u9ad8\u7528\u91cf3\u4fa1\u30ef\u30af\u30c1\u30f3\u306e\u5b9f\u4e16\u754c\u30c7\u30fc\u30bf\u306b\u57fa\u3065\u304f\u512a\u308c\u305f\u514d\u75ab\u539f\u6027\u306b\u3088\u308a\u3001IIV4-HD\u306f\u65e5\u672c\u3067\u521d\u3081\u3066\u306e\u5dee\u5225\u5316\u3055\u308c\u305f\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u30ef\u30af\u30c1\u30f3\u3068\u3057\u3066\u300160\u6b73\u4ee5\u4e0a\u306e\u6210\u4eba\u306b\u5bfe\u3059\u308b\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u304a\u3088\u3073\u305d\u306e\u5408\u4f75\u75c7\u306b\u5bfe\u3059\u308b\u3088\u308a\u9ad8\u3044\u4fdd\u8b77\u3092\u63d0\u4f9b\u3059\u308b\u3053\u3068\u304c\u671f\u5f85\u3055\u308c\u308b\u3002<\/p>\n

\"\"<\/a><\/p>\n

\"\"<\/a><\/p>\n

\"\"<\/a><\/p>\n

\"\"<\/a><\/p>\n

\"\"<\/a><\/p>\n

\u3010\u958b\u50ac\u65e5\u30112026\u5e742\u67084\u65e5<\/p>\n","protected":false},"excerpt":{"rendered":"

-\u6587\u732e\u540d- Superior immunogenicity of high-dose quadrivalent inactivated influenza vaccine versus Standard-Dose vac … \u7d9a\u304d\u3092\u8aad\u3080 \u65e5\u672c\u4eba\u9ad8\u9f62\u8005\u306b\u5bfe\u3059\u308b\u9ad8\u7528\u91cf\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u30ef\u30af\u30c1\u30f3\u306e\u6a19\u6e96\u7528\u91cf\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u30ef\u30af\u30c1\u30f3\u3068\u306e\u6bd4\u8f03\u52b9\u679c<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[5],"tags":[],"class_list":["post-2977","post","type-post","status-publish","format-standard","hentry","category-5"],"_links":{"self":[{"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/posts\/2977","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2977"}],"version-history":[{"count":1,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/posts\/2977\/revisions"}],"predecessor-version":[{"id":2984,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/posts\/2977\/revisions\/2984"}],"wp:attachment":[{"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2977"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=2977"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=2977"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}