{"id":3056,"date":"2026-11-04T12:10:23","date_gmt":"2026-11-04T03:10:23","guid":{"rendered":"https:\/\/www.hcfm.jp\/journal\/?p=3056"},"modified":"2026-11-04T12:10:23","modified_gmt":"2026-11-04T03:10:23","slug":"%e3%82%a2%e3%83%88%e3%83%94%e3%83%bc%e6%80%a7%e7%9a%ae%e8%86%9a%e7%82%8e%e3%81%ab%e5%af%be%e3%81%99%e3%82%8b%e7%b5%8c%e5%8f%a3%e6%8a%97%e3%83%92%e3%82%b9%e3%82%bf%e3%83%9f%e3%83%b3%e8%96%ac%e3%81%ae","status":"publish","type":"post","link":"https:\/\/www.hcfm.jp\/journal\/?p=3056","title":{"rendered":"\u30a2\u30c8\u30d4\u30fc\u6027\u76ae\u819a\u708e\u306b\u5bfe\u3059\u308b\u7d4c\u53e3\u6297\u30d2\u30b9\u30bf\u30df\u30f3\u85ac\u306e\u6709\u52b9\u6027"},"content":{"rendered":"

\u203b\u3053\u306e\u6642\u671f\u306eUpToDate\u306b\u3042\u308b\u201dWhat\u2019s new in family medicine\u201d\u306eTopic\u3067\u53c2\u8003\u306b\u3055\u308c\u3066\u3044\u308b\u6587\u732e\u3067\u3059\u3002<\/p>\n

\uff0d\u6587\u732e\u540d\uff0d
\nAntihistamines for atopic dermatitis (eczema): systematic review and network meta-analysis of randomised trials
\nBMJ 2026; 394 doi: https:\/\/doi.org\/10.1136\/bmj-2026-100163 (Published 29 July 2026)<\/p>\n

\uff0d\u8981\u7d04\uff0d
\nIntroduction<\/strong>
\n\u30a2\u30c8\u30d4\u30fc\u6027\u76ae\u819a\u708e\uff08\u6e7f\u75b9\uff09\u306f\u3001\u5c0f\u5150\u306e13%\u3001\u6210\u4eba\u306e7%\u304c\u7f79\u60a3\u3059\u308b\u6162\u6027\u304b\u3064\u518d\u767a\u6027\u306e\u708e\u75c7\u6027\u76ae\u819a\u75be\u60a3\u3067\u3059\u3002\u6fc0\u3057\u3044\u304b\u3086\u307f\u3068\u76ae\u819a\u306e\u708e\u75c7\u3092\u7279\u5fb4\u3068\u3059\u308b\u30a2\u30c8\u30d4\u30fc\u6027\u76ae\u819a\u708e\u306f\u3001\u60a3\u8005\u3068\u5bb6\u65cf\u306e\u751f\u6d3b\u306e\u8cea\u3001\u7cbe\u795e\u7684\u5065\u5eb7\u3001\u793e\u4f1a\u95a2\u4fc2\u3092\u640d\u306a\u3044\u307e\u3059\u3002\u7d4c\u53e3H1\u6297\u30d2\u30b9\u30bf\u30df\u30f3\u85ac\u306f\u3001\u6700\u8fd1\u306e\u82f1\u56fd\u306e\u63a8\u5b9a\u3067\u306f\u30a2\u30c8\u30d4\u30fc\u6027\u76ae\u819a\u708e\u60a3\u8005\u306e20%\u4ee5\u4e0a\u3001\u7c73\u56fd\u306e\u6700\u8fd1\u306e\u63a8\u5b9a\u3067\u306f47%\u306b\u4e00\u822c\u7684\u306b\u4f75\u7528\u3055\u308c\u308b\u8ffd\u52a0\u6cbb\u7642\u85ac\u3067\u3059\u3002\u3053\u308c\u3089\u306e\u5168\u8eab\u6027\u85ac\u5264\u306f\u3001\u598a\u5a20\u4e2d\u307e\u305f\u306f\u6388\u4e73\u4e2d\u306e\u30a2\u30c8\u30d4\u30fc\u6027\u76ae\u819a\u708e\u60a3\u8005\u306b\u3082\u6700\u3082\u591a\u304f\u51e6\u65b9\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u30a2\u30ec\u30eb\u30ae\u30fc\u6027\u9f3b\u708e\u3084\u8541\u9ebb\u75b9\u306a\u3069\u306e\u4ed6\u306e\u30a2\u30ec\u30eb\u30ae\u30fc\u75be\u60a3\u3068\u540c\u69d8\u306b\u3001\u3053\u308c\u3089\u306e\u85ac\u5264\u306e\u4f5c\u7528\u6a5f\u5e8f\u306f\u3001\u80a5\u6e80\u7d30\u80de\u3084\u597d\u5869\u57fa\u7403\u304b\u3089\u653e\u51fa\u3055\u308c\u308b\u30d2\u30b9\u30bf\u30df\u30f3\u306e\u6d3b\u6027\u3092\u963b\u5bb3\u3057\u3001\u305d\u308c\u306b\u3088\u3063\u3066\u304b\u3086\u307f\u3084\u76ae\u819a\u306e\u708e\u75c7\u3068\u3057\u3066\u73fe\u308c\u308b\u5c40\u6240\u7684\u306a\u795e\u7d4c\u7d30\u80de\u3001\u8840\u7ba1\u7d30\u80de\u3001\u708e\u75c7\u7d30\u80de\u306e\u6d3b\u6027\u5316\u3092\u6291\u5236\u3059\u308b\u3053\u3068\u3067\u3042\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u308b\u3002\u3057\u304b\u3057\u3001\u73fe\u5728\u306e\u7406\u89e3\u3067\u306f\u3001\u30a2\u30c8\u30d4\u30fc\u6027\u76ae\u819a\u708e\u306b\u4f34\u3046\u304b\u3086\u307f\u306f\u4e3b\u306b\u30d2\u30b9\u30bf\u30df\u30f3\u975e\u4f9d\u5b58\u6027\u7d4c\u8def\u304c\u95a2\u4e0e\u3057\u3066\u3044\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u308b\u3002<\/p>\n

\u7d4c\u53e3H1\u6297\u30d2\u30b9\u30bf\u30df\u30f3\u85ac\u306f\u3001\u4e00\u822c\u7684\u306b\u958b\u767a\u3055\u308c\u305f\u6642\u671f\u306b\u3088\u3063\u3066\u5206\u985e\u3055\u308c\u307e\u3059\u3002\u30af\u30ed\u30eb\u30d5\u30a7\u30cb\u30e9\u30df\u30f3\u3001\u30b8\u30d5\u30a7\u30f3\u30d2\u30c9\u30e9\u30df\u30f3\u3001\u30d2\u30c9\u30ed\u30ad\u30b7\u30b8\u30f3\u306a\u3069\u306e\u7b2c\u4e00\u4e16\u4ee3\u85ac\u5264\u306f\u8102\u6eb6\u6027\u3067\u3001\u8840\u6db2\u8133\u95a2\u9580\u3092\u5bb9\u6613\u306b\u901a\u904e\u3057\u3001\u4e2d\u67a2\u795e\u7d4c\u7cfb\u306e\u795e\u7d4c\u4f1d\u9054\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u307e\u3059\u3002\u305d\u306e\u7d50\u679c\u3001\u3053\u308c\u3089\u306e\u85ac\u5264\u306f\u795e\u7d4c\u8a8d\u77e5\u7cfb\u306e\u526f\u4f5c\u7528\u3084\u3001\u93ae\u9759\u306a\u3069\u306e\u975e\u6a19\u7684\u6297\u30b3\u30ea\u30f3\u4f5c\u7528\u3068\u95a2\u9023\u4ed8\u3051\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u81e8\u5e8a\u533b\u306f\u3001\u30d2\u30b9\u30bf\u30df\u30f3\u963b\u5bb3\u3068\u93ae\u9759\u304c\u3001\u30a2\u30c8\u30d4\u30fc\u6027\u76ae\u819a\u708e\u60a3\u8005\u304c\u7d4c\u9a13\u3059\u308b\u983b\u7e41\u306a\u304b\u3086\u307f\u3084\u7761\u7720\u969c\u5bb3\u3092\u8efd\u6e1b\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3068\u8003\u3048\u307e\u3057\u305f\u3002\u30bb\u30c1\u30ea\u30b8\u30f3\u3001\u30c7\u30b9\u30ed\u30e9\u30bf\u30b8\u30f3\u3001\u30d5\u30a7\u30ad\u30bd\u30d5\u30a7\u30ca\u30b8\u30f3\u3001\u30ec\u30dc\u30bb\u30c1\u30ea\u30b8\u30f3\u3001\u30ed\u30e9\u30bf\u30b8\u30f3\u306a\u3069\u306e\u7b2c\u4e8c\u4e16\u4ee3\u85ac\u5264\u306f\u8102\u6eb6\u6027\u304c\u4f4e\u304f\u3001\u9078\u629e\u6027\u304c\u9ad8\u3044\u305f\u3081\u3001\u795e\u7d4c\u8a8d\u77e5\u7cfb\u304a\u3088\u3073\u975e\u6a19\u7684\u306e\u526f\u4f5c\u7528\u3092\u5f15\u304d\u8d77\u3053\u3059\u53ef\u80fd\u6027\u304c\u4f4e\u304f\u306a\u308a\u307e\u3059\u3002\u4e21\u65b9\u306e\u4e16\u4ee3\u306e\u6297\u30d2\u30b9\u30bf\u30df\u30f3\u85ac\u306f\u3001\u3055\u307e\u3056\u307e\u306a\u9069\u5fdc\u75c7\u306b\u5bfe\u3057\u3066\u4e16\u754c\u4e2d\u3067\u5e02\u8ca9\u85ac\uff08\u51e6\u65b9\u7b8b\u306a\u3057\uff09\u3068\u3057\u3066\u5e83\u304f\u5165\u624b\u53ef\u80fd\u3067\u3059\u3002\u95a2\u9023\u85ac\u5264\u306b\u306f\u3001\u30b1\u30c8\u30c1\u30d5\u30a7\u30f3\uff08\u7b2c\u4e00\u4e16\u4ee3\u85ac\u5264\u304a\u3088\u3073\u80a5\u6e80\u7d30\u80de\u5b89\u5b9a\u5316\u85ac\u306b\u5206\u985e\u3055\u308c\u308b\uff09\u3084\u30af\u30ed\u30e2\u30b0\u30ea\u30af\u9178\u30ca\u30c8\u30ea\u30a6\u30e0\u3001\u30cd\u30c9\u30af\u30ed\u30df\u30eb\u30ca\u30c8\u30ea\u30a6\u30e0\uff08\u3044\u305a\u308c\u3082\u80a5\u6e80\u7d30\u80de\u5b89\u5b9a\u5316\u85ac\uff09\u306a\u3069\u304c\u3042\u308b\u3002\u305f\u3060\u3057\u3001\u3053\u308c\u3089\u306e\u85ac\u5264\u304c\u56fd\u969b\u7684\u306b\u5747\u7b49\u306b\u5165\u624b\u3067\u304d\u308b\u3068\u306f\u9650\u3089\u306a\u3044\u3002<\/p>\n

\u9577\u5e74\u306b\u308f\u305f\u308a\u4f7f\u7528\u3055\u308c\u3066\u304d\u305f\u306b\u3082\u304b\u304b\u308f\u3089\u305a\u3001\u30a2\u30c8\u30d4\u30fc\u6027\u76ae\u819a\u708e\u306e\u6cbb\u7642\u306b\u304a\u3051\u308b\u7d4c\u53e3\u6297\u30d2\u30b9\u30bf\u30df\u30f3\u85ac\u306e\u660e\u78ba\u306a\u30a8\u30d3\u30c7\u30f3\u30b9\u306b\u57fa\u3065\u304f\u5f79\u5272\u306f\u4f9d\u7136\u3068\u3057\u3066\u4e0d\u660e\u3067\u3042\u308b\u30022019\u5e74\u306e\u30b3\u30af\u30e9\u30f3\u30ec\u30d3\u30e5\u30fc\u3067\u306f\u3001\u30d7\u30e9\u30bb\u30dc\u5bfe\u7167\u8a66\u9a13\u306b\u9650\u5b9a\u3057\u3066\u300125\u306e\u8a66\u9a13\u3067\u5206\u6790\u3055\u308c\u305f21\uff5e795\u4eba\u306e\u53c2\u52a0\u8005\u306b\u3064\u3044\u3066\u4e0d\u6b63\u78ba\u3067\u7d50\u8ad6\u306e\u51fa\u306a\u3044\u7d50\u679c\u304c\u5f97\u3089\u308c\u305f\u3002\u73fe\u5728\u307e\u3067\u306b\u3001\u30d7\u30e9\u30bb\u30dc\u5bfe\u7167\u8a66\u9a13\u3068\u76f4\u63a5\u6bd4\u8f03\u8a66\u9a13\u3092\u542b\u3080\u3059\u3079\u3066\u306e\u30a8\u30d3\u30c7\u30f3\u30b9\u3092\u5358\u4e00\u306e\u7d71\u5408\u5206\u6790\u3067\u5305\u62ec\u7684\u306b\u7d71\u5408\u3057\u305f\u7814\u7a76\u306f\u4e0d\u8db3\u3057\u3066\u3044\u308b\u3002\u7c73\u56fd\u30a2\u30ec\u30eb\u30ae\u30fc\u30fb\u5598\u606f\u30fb\u514d\u75ab\u5b66\u4f1a\u3068\u7c73\u56fd\u30a2\u30ec\u30eb\u30ae\u30fc\u30fb\u5598\u606f\u30fb\u514d\u75ab\u5b66\u4f1a\u306e\u5408\u540c\u30bf\u30b9\u30af\u30d5\u30a9\u30fc\u30b9\u30fb\u30aa\u30f3\u30fb\u30d7\u30e9\u30af\u30c6\u30a3\u30b9\u30fb\u30d1\u30e9\u30e1\u30fc\u30bf\u30fc\uff08AAAAI\/ACAAI JTFPP\uff09\u306e\u30a2\u30c8\u30d4\u30fc\u6027\u76ae\u819a\u708e\u306b\u95a2\u3059\u308b\u30ea\u30d3\u30f3\u30b0\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u306e\u4e00\u74b0\u3068\u3057\u3066\u3001\u6211\u3005\u306f\u30a2\u30c8\u30d4\u30fc\u6027\u76ae\u819a\u708e\u306b\u5bfe\u3059\u308b\u7d4c\u53e3\u6297\u30d2\u30b9\u30bf\u30df\u30f3\u85ac\u3068\u80a5\u6e80\u7d30\u80de\u5b89\u5b9a\u5316\u85ac\u3092\u8a55\u4fa1\u3059\u308b\u30d7\u30e9\u30bb\u30dc\u5bfe\u7167\u304a\u3088\u3073\u76f4\u63a5\u6bd4\u8f03\u30e9\u30f3\u30c0\u30e0\u5316\u8a66\u9a13\u306e\u7cfb\u7d71\u7684\u30ec\u30d3\u30e5\u30fc\u3068\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u30e1\u30bf\u5206\u6790\u3092\u5b9f\u65bd\u3057\u305f<\/p>\n

Methods<\/strong>
\n\u30e9\u30f3\u30c0\u30e0\u52b9\u679c\u30d9\u30a4\u30ba\u30e1\u30bf\u30a2\u30ca\u30ea\u30b7\u30b9\u306b\u3088\u308a\u3001\u30a2\u30c8\u30d4\u30fc\u6027\u76ae\u819a\u708e\u306e\u91cd\u75c7\u5ea6\uff08oSCORAD\uff1a\u5ba2\u89b3\u7684\u30b9\u30b3\u30a2\u30ea\u30f3\u30b0\u30a2\u30c8\u30d4\u30fc\u6027\u76ae\u819a\u708e\u30010\uff5e83\uff1b\u6700\u5c0f\u91cd\u8981\u5dee8.2\uff1b\u4f4e\u3044\u307b\u3069\u826f\u3044\uff09\u3001\u304b\u3086\u307f\u306e\u91cd\u75c7\u5ea6\uff08\u6570\u5024\u8a55\u4fa1\u5c3a\u5ea6\u30010\uff5e10\uff1b\u6700\u5c0f\u91cd\u8981\u5dee3\uff1b\u4f4e\u3044\u307b\u3069\u826f\u3044\uff09\u3001\u7761\u7720\u969c\u5bb3\u3001\u30a2\u30c8\u30d4\u30fc\u6027\u76ae\u819a\u708e\u95a2\u9023\u306e\u751f\u6d3b\u306e\u8cea\u3001\u304a\u3088\u3073\u6709\u5bb3\u4e8b\u8c61\u3092\u7d71\u5408\u3057\u305f\u3002\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u30e1\u30bf\u30a2\u30ca\u30ea\u30b7\u30b9GRADE\uff08\u63a8\u5968\u5ea6\u8a55\u4fa1\u3001\u958b\u767a\u3001\u8a55\u4fa1\uff09\u304a\u3088\u3073\u30b3\u30a2GRADE\u30a2\u30d7\u30ed\u30fc\u30c1\u306b\u3088\u308a\u3001\u30a8\u30d3\u30c7\u30f3\u30b9\u306e\u78ba\u5b9f\u6027\u8a55\u4fa1\u304c\u884c\u308f\u308c\u305f\u3002<\/p>\n

Results<\/strong>
\n47\u4ef6\u306eRCT\u304b\u3089\u3001\u4e3b\u306b\u4e2d\u7b49\u75c7\u304b\u3089\u91cd\u75c7\u306e\u30a2\u30c8\u30d4\u30fc\u6027\u76ae\u819a\u708e\u60a3\u80056,230\u4f8b\uff08\u5c0f\u5150\u304a\u3088\u3073\u6210\u4eba\uff09\u304c\u7d71\u5408\u3055\u308c\u305f\u3002\u7b2c1\u4e16\u4ee3\u304a\u3088\u3073\u7b2c2\u4e16\u4ee3H1\u6297\u30d2\u30b9\u30bf\u30df\u30f3\u85ac\u306e\u4f75\u7528\u7642\u6cd5\u306f\u3001\u30d7\u30e9\u30bb\u30dc\u3068\u6bd4\u8f03\u3057\u3066\u75be\u60a3\u91cd\u75c7\u5ea6\uff08MD -1.87\u300195%CI -3.47\uff5e-0.27\uff09\u304a\u3088\u3073\u63bb\u75d2\u611f\uff08MD -0.89\u300195%CI -1.41\uff5e-0.37\uff09\u306e\u8efd\u5ea6\u306a\u6539\u5584\u3092\u8a8d\u3081\u305f\uff08\u4e2d\u7b49\u5ea6\u306e\u78ba\u5b9f\u6027\uff09\u3002\u3057\u304b\u3057\u3001\u3053\u308c\u3089\u306e\u5909\u5316\u306f\u7d71\u8a08\u5b66\u7684\u306b\u6709\u610f\u3067\u3042\u308b\u3082\u306e\u306e\u3001\u81e8\u5e8a\u7684\u306a\u6700\u5c0f\u91cd\u8981\u5dee\uff08MID\uff09\u306b\u306f\u9054\u3057\u3066\u3044\u306a\u304b\u3063\u305f\u3002\u7761\u7720\u969c\u5bb3\u306e\u6539\u5584\u304a\u3088\u3073\u5897\u60aa\u983b\u5ea6\u306e\u4f4e\u4e0b\u306b\u5bfe\u3059\u308b\u660e\u3089\u304b\u306a\u6709\u7528\u6027\u306f\u78ba\u8a8d\u3055\u308c\u306a\u304b\u3063\u305f\u3002\u5b89\u5168\u6027\u306b\u95a2\u3057\u3066\u306f\u3001\u7b2c1\u4e16\u4ee3\u85ac\u7269\u3067\u8a8d\u77e5\u6a5f\u80fd\u969c\u5bb3\u304a\u3088\u3073\u526f\u4f5c\u7528\u306b\u3088\u308b\u6295\u4e0e\u4e2d\u6b62\u30ea\u30b9\u30af\u306e\u4e0a\u6607\uff08RD 66\/1,000\u4eba\u300195%CI 0\uff5e231\u3001\u4e2d\u7b49\u5ea6\u306e\u78ba\u5b9f\u6027\uff09\u3092\u8a8d\u3081\u305f\u3002\u7b2c2\u4e16\u4ee3\u85ac\u7269\u306b\u304a\u3051\u308b\u8a8d\u77e5\u6a5f\u80fd\u3078\u306e\u5f71\u97ff\u306f\u85ac\u5264\u3054\u3068\u306b\u7570\u306a\u3063\u305f\uff08\u30ed\u30e9\u30bf\u30b8\u30f3\uff1a0\/1,000\u4eba\u3001\u30ec\u30dc\u30bb\u30c1\u30ea\u30b8\u30f3\uff1a16\/1,000\u4eba\u3001\u30bb\u30c1\u30ea\u30b8\u30f3\uff1a17\/1,000\u4eba\uff09<\/p>\n

41,381 \u4ef6\u306e\u8a18\u9332\u30014,288 \u4ef6\u306e\u95a2\u9023\u6027\u306e\u9ad8\u3044\u53ef\u80fd\u6027\u306e\u3042\u308b\u5168\u6587\u304c\u7279\u5b9a\u3055\u308c\u3001\u6700\u7d42\u7684\u306b 47 \u4ef6\u306e\u72ec\u81ea\u306e\u30e9\u30f3\u30c0\u30e0\u5316\u6bd4\u8f03\u8a66\u9a13\u304c\u542b\u307e\u308c\u307e\u3057\u305f(\u56f3\uff11)\u3002\u3053\u308c\u3089\u306e\u7814\u7a76\u306b\u306f 6,230 \u4eba\u306e\u53c2\u52a0\u8005\u304c\u542b\u307e\u308c\u3001\u5831\u544a\u3055\u308c\u305f\u5e73\u5747\u5e74\u9f62\u306e\u4e2d\u592e\u5024\u306f 20 \u6b73 (\u5e73\u5747\u5024\u306e\u7bc4\u56f2\u306f 1 \uff5e 43 \u6b73) \u3067\u3057\u305f\u3002\u53c2\u52a0\u8005\u306e\u4e2d\u592e\u5024\u306752%\u304c\u5973\u6027\u3067\u3042\u308a\u300127\uff0857%\uff09\u306e\u8a66\u9a13\u306b\u306f\u5c0f\u5150\u53c2\u52a0\u8005\u304c\u542b\u307e\u308c\u300131\uff0866%\uff09\u306f\u30d7\u30e9\u30bb\u30dc\u5bfe\u7167\u8a66\u9a13\u3067\u3042\u308a\u300137\uff0879%\uff09\u306f\u4e26\u884c\u8a66\u9a13\u30c7\u30b6\u30a4\u30f3\u3067\u3042\u308a\u300136\uff0877%\uff09\u306e\u8a66\u9a13\u3067\u306f\u3059\u3079\u3066\u306e\u53c2\u52a0\u8005\u306b\u5bfe\u3057\u3066\u4f75\u7528\u80cc\u666f\u6cbb\u7642\uff08\u4fdd\u6e7f\u5264\u307e\u305f\u306f\u5c40\u6240\u30b3\u30eb\u30c1\u30b3\u30b9\u30c6\u30ed\u30a4\u30c9\uff09\u306e\u4f7f\u7528\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3057\u305f\u3002\u307b\u3068\u3093\u3069\u306e\u8a66\u9a13\u3067\u306f\u3001\u4e2d\u7b49\u5ea6\u304b\u3089\u91cd\u5ea6\u306e\u30a2\u30c8\u30d4\u30fc\u6027\u76ae\u819a\u708e\u306e\u53c2\u52a0\u8005\u304c\u542b\u307e\u308c\u3066\u3044\u308b\u3068\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3057\u305f\u30024\u3064\u306e\u8a66\u9a13\u3067\u306f\u30011\u65e52\u500d\u4ee5\u4e0a\u306e\u7528\u91cf\u306e\u6297\u30d2\u30b9\u30bf\u30df\u30f3\u5264\u304c\u8abf\u67fb\u3055\u308c\u307e\u3057\u305f\u3002\u8868\uff11\u306f\u3001\u542b\u307e\u308c\u305f\u8a66\u9a13\u306e\u7279\u5fb4\u3092\u307e\u3068\u3081\u305f\u3082\u306e\u3067\u3059\u3002\u80cc\u666f\u6cbb\u7642\u306e\u4f7f\u7528\u3092\u5831\u544a\u3057\u305f\u8a66\u9a13\u3068\u3001\u4f7f\u7528\u3092\u5831\u544a\u3057\u3066\u3044\u306a\u3044\u8a66\u9a13\u306e\u9593\u3067\u4e00\u8cab\u3057\u305f\u52b9\u679c\u304c\u898b\u3089\u308c\u307e\u3057\u305f\uff08\u88dc\u8db3\u8cc7\u6599\u3092\u53c2\u7167\uff09\u3002<\/p>\n

\"\"<\/a>
\n\u88681 \u30a2\u30c8\u30d4\u30fc\u6027\u76ae\u819a\u708e\uff08\u6e7f\u75b9\uff09\u306b\u5bfe\u3059\u308b\u6297\u30d2\u30b9\u30bf\u30df\u30f3\u85ac\u306e\u30e9\u30f3\u30c0\u30e0\u5316\u6bd4\u8f03\u8a66\u9a13\u306e\u7279\u5fb4<\/p>\n

\"\"<\/a><\/p>\n

Conclusion<\/strong>
\n\u30a2\u30c8\u30d4\u30fc\u6027\u76ae\u819a\u708e\u306b\u5bfe\u3059\u308bH1\u53d7\u5bb9\u4f53\u62ee\u6297\u85ac\u306e\u8ffd\u52a0\u7642\u6cd5\u306f\u3001\u75be\u60a3\u306e\u5897\u60aa\u3084\u75d2\u307f\u3092\u308f\u305a\u304b\u306b\u6291\u3048\u308b\u306b\u3068\u3069\u307e\u308a\u3001\u81e8\u5e8a\u7684\u6700\u5c0f\u91cd\u8981\u5dee\u3092\u6e80\u305f\u3059\u3082\u306e\u3067\u306f\u306a\u3044\u3002\u307e\u305f\u3001\u7761\u7720\u30c8\u30e9\u30d6\u30eb\u3084\u75c5\u72b6\u60aa\u5316\u306b\u5bfe\u3059\u308b\u6291\u5236\u52b9\u679c\u3082\u4e4f\u3057\u3044\u3068\u8003\u3048\u3089\u308c\u308b\u3002\u7b2c1\u4e16\u4ee3\u85ac\u7269\u3067\u306f\u93ae\u9759\u4f5c\u7528\u3092\u306f\u3058\u3081\u3068\u3059\u308b\u4e2d\u67a2\u795e\u7d4c\u7cfb\u3078\u306e\u5f71\u97ff\u304b\u3089\u6709\u5bb3\u4e8b\u8c61\u306b\u3088\u308b\u670d\u85ac\u4e2d\u65ad\u3092\u5897\u52a0\u3055\u305b\u308b\u6050\u308c\u304c\u3042\u308a\u3001\u7b2c2\u4e16\u4ee3\u85ac\u7269\u3067\u306e\u5f71\u97ff\u306f\u6210\u5206\u306b\u3088\u308a\u7570\u306a\u308b\u3002\u3057\u305f\u304c\u3063\u3066\u3001\u672c\u75be\u60a3\u306b\u5bfe\u3059\u308b\u6297\u30d2\u30b9\u30bf\u30df\u30f3\u85ac\u306e\u5b9a\u5e38\u7684\u306a\u51e6\u65b9\u3092\u63a8\u5968\u3057\u306a\u3044\u6839\u62e0\u3068\u306a\u308a\u3001\u4eca\u5f8c\u306e\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u898b\u76f4\u3057\u3092\u88cf\u4ed8\u3051\u308b\u7d50\u679c\u3067\u3042\u308b\u3002<\/p>\n

\"\"<\/a>
\n\u56f3\uff12\u3000\u6cbb\u7642\u30af\u30e9\u30b9\u304a\u3088\u3073\u500b\u3005\u306e\u85ac\u5264\u306b\u3088\u308b\u30a2\u30c8\u30d4\u30fc\u6027\u76ae\u819a\u708e\u306e\u91cd\u75c7\u5ea6\u306e\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u30d7\u30ed\u30c3\u30c8\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n

\"\"<\/a>
\n\u56f3\uff13\u3000\u60a3\u8005\u306b\u3068\u3063\u3066\u91cd\u8981\u306a\u30a2\u30c8\u30d4\u30fc\u6027\u76ae\u819a\u708e\u306e\u30a2\u30a6\u30c8\u30ab\u30e0\u306b\u5bfe\u3059\u308b\u6297\u30d2\u30b9\u30bf\u30df\u30f3\u85ac\u306e\u6bd4\u8f03\u52b9\u679c\u306e GRADE \u8981\u7d04\u8868\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n

Discussion<\/strong>
\n\u4e3b\u306a\u8abf\u67fb\u7d50\u679c
\n47\u4ef6\u306e\u30e9\u30f3\u30c0\u30e0\u5316\u6bd4\u8f03\u8a66\u9a13\u306b\u53c2\u52a0\u3057\u305f6230\u540d\u306e\u88ab\u9a13\u8005\u3092\u5bfe\u8c61\u3068\u3057\u305f\u3053\u306e\u7cfb\u7d71\u7684\u30ec\u30d3\u30e5\u30fc\u3068\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u30e1\u30bf\u30a2\u30ca\u30ea\u30b7\u30b9\u3067\u306f\u3001\u30a2\u30c8\u30d4\u30fc\u6027\u76ae\u819a\u708e\u60a3\u8005\u306b\u304a\u3044\u3066\u3001\u7b2c\u4e00\u4e16\u4ee3\u307e\u305f\u306f\u7b2c\u4e8c\u4e16\u4ee3\u306eH1\u6297\u30d2\u30b9\u30bf\u30df\u30f3\u85ac\u3092\u8ffd\u52a0\u3057\u3066\u3082\u3001\u30a2\u30c8\u30d4\u30fc\u6027\u76ae\u819a\u708e\u306e\u91cd\u75c7\u5ea6\u3001\u304b\u3086\u307f\u3001\u7761\u7720\u969c\u5bb3\u3001\u307e\u305f\u306f\u30a2\u30c8\u30d4\u30fc\u6027\u76ae\u819a\u708e\u306e\u60aa\u5316\u306f\u6709\u610f\u306b\u6539\u5584\u3055\u308c\u306a\u3044\u3053\u3068\u304c\u308f\u304b\u3063\u305f\u3002\u7b2c\u4e00\u4e16\u4ee3\u306eH1\u6297\u30d2\u30b9\u30bf\u30df\u30f3\u85ac\u306f\u3001\u93ae\u9759\u3084\u7720\u6c17\u306a\u3069\u306e\u8a8d\u77e5\u6a5f\u80fd\u969c\u5bb3\u3092\u5897\u52a0\u3055\u305b\u3001\u307e\u305f\u3001\u7b2c\u4e00\u4e16\u4ee3\u306e\u85ac\u5264\u306f\u6709\u5bb3\u4e8b\u8c61\u306b\u3088\u308b\u6cbb\u7642\u4e2d\u6b62\u3082\u5897\u52a0\u3055\u305b\u305f\u3002\u7b2c\u4e8c\u4e16\u4ee3\u306e\u85ac\u5264\u306b\u304a\u3051\u308b\u8a8d\u77e5\u6a5f\u80fd\u969c\u5bb3\u30ea\u30b9\u30af\u306e\u30d9\u30a4\u30ba\u5206\u6790\u3067\u306f\u3001\u500b\u3005\u306e\u6297\u30d2\u30b9\u30bf\u30df\u30f3\u85ac\u9593\u3067\u5dee\u304c\u898b\u3089\u308c\u305f\u3002\u30ed\u30e9\u30bf\u30b8\u30f3\u306f\u30d7\u30e9\u30bb\u30dc\u3088\u308a\u3082\u8a8d\u77e5\u6a5f\u80fd\u969c\u5bb3\u3092\u5897\u52a0\u3055\u305b\u306a\u3044\u304c\u3001\u30bb\u30c1\u30ea\u30b8\u30f3\u3068\u30ec\u30dc\u30bb\u30c1\u30ea\u30b8\u30f3\u306f\u8a8d\u77e5\u6a5f\u80fd\u969c\u5bb3\u3092\u5897\u52a0\u3055\u305b\u305f\u3002\u691c\u8a0e\u3057\u305f\u6297\u30d2\u30b9\u30bf\u30df\u30f3\u85ac\u306f\u3044\u305a\u308c\u3082\u3001\u691c\u8a0e\u671f\u9593\u3092\u901a\u3058\u3066\u91cd\u7be4\u306a\u6709\u5bb3\u4e8b\u8c61\u3092\u5897\u52a0\u3055\u305b\u306a\u304b\u3063\u305f\u3002\u3053\u308c\u3089\u306e\u7d50\u679c\u306f\u3001\u88ab\u9a13\u8005\u306e\u5e74\u9f62\u5c64\u3001\u8a66\u9a13\u30c7\u30b6\u30a4\u30f3\u3001\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3\u306e\u30a2\u30c8\u30d4\u30fc\u6027\u76ae\u819a\u708e\u306e\u91cd\u75c7\u5ea6\u3001\u6cbb\u7642\u671f\u9593\u3001\u304a\u3088\u30731\u65e5\u306e\u7dcf\u6295\u4e0e\u91cf\u306b\u95a2\u308f\u3089\u305a\u4e00\u8cab\u3057\u3066\u3044\u305f\u3002
\n\u3010\u4eca\u56de\u306e\u7814\u7a76\u306e\u9650\u754c\u3011
\n\u8a66\u9a13\u5bfe\u8c61\u96c6\u56e3\u306f\u3001\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3\u306e\u91cd\u75c7\u5ea6\u304c\u7570\u306a\u3063\u3066\u3044\u305f\u3002\u305d\u306e\u305f\u3081\u3001\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3\u304b\u3089\u306e\u5909\u5316\u3092\u5206\u6790\u3057\u3001ICEMAN\u3092\u7528\u3044\u305f\u69cb\u9020\u5316\u8a55\u4fa1\u3092\u5b9f\u65bd\u3059\u308b\u3053\u3068\u3067\u3053\u306e\u9650\u754c\u306b\u5bfe\u51e6\u3057\u3001\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3\u306e\u91cd\u75c7\u5ea6\u306e\u7bc4\u56f2\u5168\u4f53\u306b\u308f\u305f\u3063\u3066\u52b9\u679c\u304c\u8a8d\u3081\u3089\u308c\u306a\u3044\u3053\u3068\u3092\u4e00\u8cab\u3057\u3066\u78ba\u8a8d\u3057\u305f\u3002\u3055\u3089\u306b\u3001\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3\u306e\u91cd\u75c7\u5ea6\u3092\u8abf\u6574\u3057\u305f\u611f\u5ea6\u5206\u6790\u306f\u3001\u4e3b\u8981\u5206\u6790\u3068\u4e00\u81f4\u3059\u308b\u3053\u3068\u304c\u8a3c\u660e\u3055\u308c\u305f\u3002\u3057\u304b\u3057\u3001\u30b5\u30d6\u30b0\u30eb\u30fc\u30d7\u5206\u6790\u306f\u3001\u81e8\u5e8a\u7684\u306b\u91cd\u8981\u306a\u52b9\u679c\u4fee\u98fe\u306b\u5bfe\u3059\u308b\u7d71\u8a08\u7684\u88cf\u4ed8\u3051\u306f\u307b\u3068\u3093\u3069\u5f97\u3089\u308c\u305a\u3001\u30b5\u30d6\u30b0\u30eb\u30fc\u30d7\u306e\u30b5\u30f3\u30d7\u30eb\u30b5\u30a4\u30ba\u304c\u5c0f\u3055\u3044\u305f\u3081\u9650\u754c\u304c\u3042\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b<\/p>\n

\u3010\u958b\u50ac\u65e5\u30112026\u5e7411\u67084\u65e5\uff08\u6c34\uff09<\/p>\n","protected":false},"excerpt":{"rendered":"

\u203b\u3053\u306e\u6642\u671f\u306eUpToDate\u306b\u3042\u308b\u201dWhat\u2019s new in family medicine\u201d\u306eTopic\u3067\u53c2\u8003\u306b\u3055\u308c\u3066\u3044\u308b\u6587\u732e\u3067\u3059\u3002 \uff0d\u6587\u732e\u540d\uff0d Antihistamines for atopic dermatiti … \u7d9a\u304d\u3092\u8aad\u3080 \u30a2\u30c8\u30d4\u30fc\u6027\u76ae\u819a\u708e\u306b\u5bfe\u3059\u308b\u7d4c\u53e3\u6297\u30d2\u30b9\u30bf\u30df\u30f3\u85ac\u306e\u6709\u52b9\u6027<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[33,23],"tags":[],"class_list":["post-3056","post","type-post","status-publish","format-standard","hentry","category-whats-new","category-23"],"_links":{"self":[{"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/posts\/3056","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=3056"}],"version-history":[{"count":1,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/posts\/3056\/revisions"}],"predecessor-version":[{"id":3061,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/posts\/3056\/revisions\/3061"}],"wp:attachment":[{"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=3056"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=3056"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=3056"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}