\u3010\u6587\u732e\u540d\u3011\u00a0
\n\u8457\u8005\u540d\uff1aGerber Y.et al.
\n\u6587\u732e\u30bf\u30a4\u30c8\u30eb\uff1aSmoking reduction at midlife and lifetime mortality risk in men a prospective cohort study.\u00a0
\n\u96d1\u8a8c\u540d\u30fb\u66f8\u7c4d\u540d\uff1aAm J Epidemiol.
\n\u767a\u884c\u5e74\uff1a2012 May 15;175(10):1006-12.<\/p>\n
\u3010\u8981\u7d04\u3011
\n\uff1cBackground\uff1e
\nPrevious studies have not shown a survival advantage for smoking reduction. The authors assessed survival and life expectancy according to changes in smoking intensity in a cohort of Israeli working men.\u00a0<\/p>\n
\uff1cMethods\uff1e
\nBaseline smokers recruited in 1963 were reassessed in 1965 (n = 4,633; mean age, 51 years). Smoking behavior was self-reported (5 status : never smoker \/ past smoker \/ 1-10 \/ 11-20 \/ more than 20 cigarettes per days) respectively. They were followed up prospectively for mortality through 2005. Smoking intensity at both time points was self-reported and categorized as none, 1-10, 11-20, and \u226521 cigarettes per day.\u00a0<\/p>\n
\uff1cResults\uff1e
\nChange between smoking categories was noted, and participants were classified as increased (8%), maintained (65%), reduced (17%), or quit (10%) smoking (Table 1). During a median follow-up of 26 (quartiles 1-3: 16-35) years, 87% of participants died. Changes in intensity were associated with survival. In multivariable-adjusted models, the hazard ratios for mortality were 1.14 (95% confidence interval (CI): 0.99, 1.32) among increasers, 0.85 (95% CI: 0.77, 0.95) among reducers, and 0.78 (95% CI: 0.69, 0.89) among quitters, compared with maintainers (Table 3). Inversely, the adjusted odds ratios of surviving to age 80 years were 0.77 (95% CI: 0.60, 0.98), 1.22 (95% CI: 1.01, 1.47), and 1.33 (95% CI: 1.07, 1.66), respectively. The survival benefit associated with smoking reduction was mostly evident among heavy smokers and for cardiovascular disease mortality.\u00a0<\/p>\n
\uff1cConclusion\uff1e
\nThese results suggest that decreasing smoking intensity should be considered as a risk-reduction strategy for heavy smokers who cannot quit abruptly.<\/p>\n
\uff1cLimitation\uff1e
\n\u30fbNo information is available on smoking habits throughout follow-up.
\n\u30fbThere was more factors that should adjusted detail. For example dietary and physical activity patterns.
\n\u30fbThis study is a male-only cohort.<\/p>\n
\u3010\u958b\u50ac\u65e5\u3011
\n2012\u5e748\u670829\u65e5<\/p>\n","protected":false},"excerpt":{"rendered":"
\u3010\u6587\u732e\u540d\u3011\u00a0 \u8457\u8005\u540d\uff1aGerber Y.et al. \u6587\u732e\u30bf\u30a4\u30c8\u30eb\uff1aSmoking reduction at midlife and lifetime mortality risk in men a prospectiv … \u7d9a\u304d\u3092\u8aad\u3080 If you cannot quit abruptly, only “reduction” of smoking will be of benefit to you !<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[5],"tags":[],"class_list":["post-361","post","type-post","status-publish","format-standard","hentry","category-5"],"_links":{"self":[{"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/posts\/361","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=361"}],"version-history":[{"count":1,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/posts\/361\/revisions"}],"predecessor-version":[{"id":362,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/posts\/361\/revisions\/362"}],"wp:attachment":[{"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=361"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=361"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=361"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}