\u3010\u6587\u732e\u540d\u3011
\n\u8457\u8005\u540d\uff1aF. Fang MD et al
\n\u6587\u732e\u30bf\u30a4\u30c8\u30eb\uff1aSuicide and Cardiovascular Death after a Cancer Diagnosis.
\n\u96d1\u8a8c\u540d\u30fb\u66f8\u7c4d\u540d\uff1aN Engl J Med 2012; 366 : 1310 – 8.
\n\u767a\u884c\u5e74\uff1a2012<\/p>\n
\u3010\u8981\u7d04\u3011
\n\uff1cBackground\uff1e
\nReceiving a diagnosis of cancer is a traumatic experience that may trigger immediate adverse health consequences beyond the effects of the disease or treatment.<\/p>\n
\uff1cMethods\uff1e
\nUsing Poisson and negative binomial regression models, Researchers conducted a historical cohort study involving 6,073,240 Swedes to examine the associations between a cancer diagnosis and the immediate risk of suicide or death from cardiovascular causes from 1991 through 2006.\u00a0
\nTo adjust for unmeasured confounders, they also performed a nested, self-matched case-crossover analysis among all patients with cancer who died from suicide or cardiovascular diseases in the cohort.<\/p>\n
\uff1cResults\uff1e
\nAs compared with cancer-free persons, the relative risk of suicide among patients receiving a cancer diagnosis was 12.6 (95% confidence interval [CI], 8.6 to 17.8) during the first week (29 patients; incidence rate, 2.50 per 1000 person-years) and 3.1 (95% CI, 2.7 to 3.5) during the first year (260 patients; incidence rate, 0.60 per 1000 personyears).
\nThe relative risk of cardiovascular death after diagnosis was 5.6 (95% CI, 5.2 to 5.9) during the first week (1318 patients; incidence rate, 116.80 per 1000 person-years) and 3.3 (95% CI, 3.1 to 3.4) during the first 4 weeks (2641 patients; incidence rate, 65.81 per 1000 person-years). The risk elevations decreased rapidly during the first year after diagnosis.\u00a0
\nIncreased risk was particularly prominent for cancers with a poor prognosis. The case-crossover analysis largely confirmed results from the main analysis.<\/p>\n
\uff1cConclusions\uff1e
\nIn this large cohort study, patients who had recently received a cancer diagnosis had increased risks of both suicide and death from cardiovascular causes, as compared with cancer-free persons.\u00a0<\/p>\n
\u3010\u958b\u50ac\u65e5\u3011
\n2012\u5e745\u670830\u65e5<\/p>\n","protected":false},"excerpt":{"rendered":"
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