{"id":668,"date":"2011-01-26T09:32:25","date_gmt":"2011-01-26T00:32:25","guid":{"rendered":"http:\/\/www.hcfm.jp\/journal\/?p=668"},"modified":"2015-08-07T10:33:32","modified_gmt":"2015-08-07T01:33:32","slug":"hpv%e3%83%af%e3%82%af%e3%83%81%e3%83%b3%e3%81%ae%e6%9c%89%e5%8a%b9%e6%80%a7%e3%81%a8%e8%b2%bb%e7%94%a8%e5%af%be%e5%8a%b9%e6%9e%9c","status":"publish","type":"post","link":"https:\/\/www.hcfm.jp\/journal\/?p=668","title":{"rendered":"HPV\u30ef\u30af\u30c1\u30f3\u306e\u6709\u52b9\u6027\u3068\u8cbb\u7528\u5bfe\u52b9\u679c"},"content":{"rendered":"

\u3010\u6587\u732e\u540d\u3011\u2028Philip Castle: Recommendations for the use of human papillomavirus vaccines. UpToDate ONLINE 18.3: 2010. \u2028\u4eca\u91ce\u826f\uff1aHPV\u30ef\u30af\u30c1\u30f3\u306b\u3088\u308b\u5b50\u5bae\u981a\u304c\u3093\u4e88\u9632\uff0eJIM\uff1a\uff50258\u3001vol.20 No.4 2010\u2028\u4e95\u4e0a\u6b63\u6a39\uff1aHPV\u30ef\u30af\u30c1\u30f3\u306e\u63a5\u7a2e\u6642\u671f\uff65\u6297\u4f53\u4fa1\uff65\u7b4b\u8089\u5185\u6ce8\u5c04\u306e\u7406\u7531\uff0e\u65e5\u672c\u533b\u4e8b\u65b0\u5831\uff0ep81\u30012010\u5e744\u67083\u65e5\u2028\u795e\u8c37\u658e(\u3072\u3068\u3057)\uff1aHPV\u30ef\u30af\u30c1\u30f3\uff0e\u5c0f\u5150\u79d1\u8a3a\u7642\uff1a\uff502345\u30012009\u5e7412\u6708\u53f7\uff0e\u2028\u2028\u2028\u2028\u3010\u8981\u7d04\u3011
\n\u3010Up to Date\u3011\u3088\u308a\u2028\u521d\u4ea4\u4ee5\u524d\u306e\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\uff0d\u3000\u81e8\u5e8a\u8a66\u9a13\u306e\u7d50\u679c\u304b\u3089\u3001HPV\u30ef\u30af\u30c1\u30f3\u306fHPV\u672a\u611f\u67d3\u306e\u4eba\u305f\u3061\u306b\u6700\u3082\u6709\u52b9\u3067\u3042\u308b\u3002(\u521d\u4ea4\u4ee5\u524d\u306a\u3069)\u3000\u306a\u305c\u306a\u3089HPV\u30ef\u30af\u30c1\u30f3\u306f\u4e88\u9632\u3067\u3042\u308a\u3001\u6cbb\u7642\u3067\u306f\u306a\u3044\u306e\u3067\u3001\u3059\u3067\u306b\u611f\u67d3\u3057\u3066\u3044\u308b16\u578b\u307e\u305f\u306f18\u578b\u306eHPV\u304c\u767a\u75c7\u3059\u308b\u3053\u3068\u3092\u9632\u3050\u3053\u3068\u306f\u51fa\u6765\u306a\u3044\u3002\u30ef\u30af\u30c1\u30f3\u3092\u884c\u3048\u3070\u3001\u3053\u308c\u3089\u306e\u30bf\u30a4\u30d7\u306eHPV\u306b\u5bfe\u3059\u308b\u4fdd\u8b77\u7684\u306a\u514d\u75ab\u304c\u3067\u304d\u308b\u3002\u30a2\u30e1\u30ea\u30ab\u5408\u8846\u56fd\u3067\u306f9\u6b73\u304b\u308926\u6b73\u306e\u9593\u306e\u5168\u3066\u306e\u5973\u6027\u306bHPV\u30ef\u30af\u30c1\u30f3\u304c\u63a8\u5968\u3055\u308c\u3066\u3044\u308b\u3002<\/p>\n

\u8cbb\u7528\u5bfe\u52b9\u679c\u3000\u2015\u3000HPV\u30ef\u30af\u30c1\u30f3\u306e\u8cbb\u7528\u5bfe\u52b9\u679c\u304c\u8907\u6570\u306e\u7814\u7a76\u306b\u304a\u3044\u3066\u6570\u5b66\u7684\u306b\u691c\u8a3c\u3055\u308c\u305f\u3002\u3042\u308b\u7814\u7a76\u3067\u306f\u3001\u7c73\u56fd12\u6b73\u306e\u5973\u5150\u5168\u54e1\u306b\u63a5\u7a2e\u3059\u308b\u3053\u3068\u3067\u300120\u4e07\u4ee5\u4e0a\u306eHPV\u306e\u611f\u67d3\u3092\u4e88\u9632\u3057\u300110\u4e07\u4ee5\u4e0a\u306e\u9838\u90e8\u7d30\u80de\u8a3a\u306e\u7570\u5e38\u3092\u4e88\u9632\u3057\u3001\u8fd1\u5e74\u306e\u63a8\u5968\u901a\u308a\u306b\u9838\u90e8\u304c\u3093\u691c\u8a3a\u3092\u7d99\u7d9a\u3059\u308c\u30703300\u4f8b\u306e\u5b50\u5bae\u9838\u764c\u3092\u4e88\u9632\u3059\u308b\u3068\u793a\u3057\u3066\u3044\u308b\u3002\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u5e74\u9f62\u304c\u5897\u3059\u306b\u3064\u308c\u8cbb\u7528\u5bfe\u52b9\u679c\u306f\u4f4e\u4e0b\u3057\u3066\u3044\u304f\u3002HPV\u30ef\u30af\u30c1\u30f3\u304c\u7d42\u751f\u514d\u75ab\u3068\u4eee\u5b9a\u3059\u308b\u3068\u300112\u6b73\u306e\u5c11\u5973\u306b\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u3057\u305f\u5834\u5408\u3001\u8cbb\u7528\u5bfe\u52b9\u679c\u306f1QALY\uff08quality-adjusted life-year\uff09\u3042\u305f\u308a$43,600\u3068\u3044\u3046\u5831\u544a\u304c\u3042\u308b\u4e00\u65b9\u3001\u5225\u306e\u5831\u544a\u3067\u306f26\u6b73\u307e\u3067\u7bc4\u56f2\u3092\u62e1\u5927\u3057\u3066\u4e88\u9632\u63a5\u7a2e\u3092\u884c\u3063\u305f\u5834\u5408\u306f1QALY\u3042\u305f\u308a$152,700\u307e\u3067\u4e0a\u6607\u3059\u308b\u3002<\/p>\n

\u2028\u2028\u3010JIM\u3011\u3088\u308a
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\u3010\u65e5\u672c\u533b\u4e8b\u65b0\u5831\u3011\u3088\u308a
\n\u2028\u611f\u67d3\u8005\u306e90\uff05\u306fHPV\u306f2\u5e74\u4ee5\u5185\u306b\u6d88\u5931\u3057\u3066\u3044\u308b\u3002\u65e5\u672c\u306b\u304a\u3044\u3066\u306f\u300110\u4ee3\u5f8c\u534a\u308420\u4ee3\u524d\u534a\u3067\u306f50\uff05\u306e\u611f\u67d3\u7387\u3067\u3042\u308b\u304c\u300140\u6b73\u4ee3 \u4ee5\u964d\u306b\u306a\u308b\u30685\uff5e10\uff05\u3067\u3042\u308b\u3002\u2028\u2028<\/p>\n

\u3010\u5c0f\u5150\u79d1\u8a3a\u7642\u3011\u3088\u308a\u2028
\n\u5973\u6027(16\uff5e26\u6b73)\u3092\u5bfe\u8c61\u3068\u3057\u305f\uff14\u4fa1HPV\u30ef\u30af\u30c1\u30f3\u306e\u7b2c\u2161\u304a\u3088\u3073\u2162\u76f8\u8a66\u9a13\u306e\u7d71\u5408\u89e3\u6790\u7d50\u679c\u3067\u306f\u3001\u30ef\u30af\u30c1\u30f3\u542b\u6709\u306eHPV16\u304a\u3088\u307318\u578b\u306b\u672a\u611f\u67d3\u3060\u3063\u305f\u5834\u5408\u3001\u3053\u308c\u3089\u306b\u95a2\u9023\u3057\u305f\u5b50\u5bae\u9838\u90e8\u524d\u304c\u3093\u75c5\u5909\u306e\u4e88\u9632\u306b\u95a2\u3057\u306699\uff05\u306e\u4e88\u9632\u6709\u52b9\u7387\u304c\u793a\u3055\u308c\u3066\u3044\u308b\u3002\uff12\u4fa1HPV\u30ef\u30af\u30c1\u30f3\u3067\u3082\uff11\uff16\u578b\u304a\u3088\u3073\uff11\uff18\u578b\u306b\u3088\u308b\u524d\u304c\u3093\u75c5\u5909\u306b\u5bfe\u3057\u306690\uff05\u3092\u8d85\u3048\u308b\u9ad8\u3044\u4e88\u9632\u52b9\u679c\u304c\u793a\u3055\u308c\u3066\u3044\u308b\u3002\u2028\u3000\u3059\u3067\u306b\u6027\u4ea4\u7d4c\u9a13\u304c\u3042\u308b\u5973\u6027\u306b\u5bfe\u3057\u3066\u3082\u63a5\u7a2e\u3092\u5968\u52b1\u3057\u3066\u304a\u308a\u300113\uff5e26\u6b73\u306e\u5973\u6027\u3092\u30ad\u30e3\u30c3\u30c1\u30a2\u30c3\u30d7\u63a5\u7a2e\u306e\u5bfe\u8c61\u3068\u3057\u3066\u3044\u308b\u30024\u4fa1\u30ef\u30af\u30c1\u30f3\u3067\u306e\u81e8\u5e8a\u8a66\u9a13\u3067\u3001HPV\u65e2\u611f\u67d3\u8005\u3082\u542b\u3080\u6700\u4f4e1\u56de\u306e\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u3092\u53d7\u3051\u305fITT(intension-to-treat)\u7fa4\u3092\u89e3\u6790\u3057\u305f\u7d50\u679c\u3067\u306f44\uff05\u306e\u4e88\u9632\u52b9\u679c\u304c\u8a8d\u3081\u3089\u308c\u305f\u3053\u3068\u304b\u3089\u3001\u30ad\u30e3\u30c3\u30c1\u30a2\u30c3\u30d7\u7fa4\u3067\u306e\u6709\u7528\u6027\u3082\u3042\u308b\u3082\u306e\u3068\u8003\u3048\u3089\u308c\u308b\u3002\u2028<\/p>\n

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\n\u3000\u5f53\u521d\u3001\uff12\uff17\u6b73\u4ee5\u964d\u306e\u6027\u4ea4\u7d4c\u9a13\u306e\u3042\u308b\u5973\u6027\u306b\u5bfe\u3059\u308bHPV\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u306e\u6709\u52b9\u6027\u306b\u3064\u3044\u3066\u8abf\u3079\u305f\u304b\u3063\u305f\u304c\u3001\u6709\u7528\u306a\u60c5\u5831\u306f\u5f97\u3089\u308c\u306a\u304b\u3063\u305f\u3002\u2028\u3000\u3057\u304b\u3057\u63a5\u7a2e\u5e74\u9f62\u3092\u62e1\u5927\u3057\u3066\u884c\u304f\u306b\u9023\u308c\u3066\u8cbb\u7528\u5bfe\u52b9\u679c\u306f\u4e0b\u304c\u3063\u3066\u3044\u304f\uff08\u30b3\u30b9\u30c8\u304c\u4e0a\u6607\u3057\u3066\u3044\u304f\uff09\u3053\u3068\u3092\u8003\u3048\u308b\u3068\u3001\u63a5\u7a2e\u3092\u63a8\u5968\u3059\u308b\u5e74\u9f62\u306b\u306f\u4e00\u5b9a\u306e\u7dda\u5f15\u304d\u304c\u5fc5\u8981\u3067\u3042\u308d\u3046\u3002\u2028\u3000\uff12\uff17\u6b73\u4ee5\u4e0a\u306e\u6027\u4ea4\u7d4c\u9a13\u306e\u3042\u308b\u5973\u6027\u500b\u4eba\u306e\u30ec\u30d9\u30eb\u3067\u8003\u3048\u308b\u3068\u3001HPV\u306e\u81ea\u7136\u611f\u67d3\u3067\u306f\u514d\u75ab\u306f\u5f97\u3089\u308c\u305a\u7e70\u308a\u8fd4\u3057\u611f\u67d3\u3059\u308b\u305f\u3081\u3001\u63a8\u5968\u5e74\u9f62\u3092\u904e\u304e\u3066\u3082HPV\u30ef\u30af\u30c1\u30f3\u3092\u63a5\u7a2e\u3057\u3066\u514d\u75ab\u3092\u5f97\u308b\u3053\u3068\u306e\u610f\u7fa9\u304c\u306a\u3044\u3068\u306f\u3044\u3048\u306a\u3044\u4e00\u65b9\u3067\u6027\u4ea4\u306e\u30d1\u30fc\u30c8\u30ca\u30fc\u304c\u304a\u4e92\u3044\u306b\u56fa\u5b9a\u3055\u308c\u3066\u3044\u308b\u5834\u5408\u3001\u518d\u611f\u67d3\u306e\u30ea\u30b9\u30af\u306f\u5c11\u306a\u3044\u3002\u2028\u57fa\u672c\u7684\u306b\u306f\u5065\u8a3a\u3092\u5b9a\u671f\u7684\u306b\u53d7\u3051\u308b\u3053\u3068\u3092\u63a8\u5968\u3057\u3001\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u306b\u3064\u3044\u3066\u306f\u500b\u5225\u306b\u3088\u304f\u691c\u8a0e\u3059\u308b\u5fc5\u8981\u304c\u3042\u308b\u3002\u2028<\/p>\n

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\u3010\u6587\u732e\u540d\u3011\u2028Philip Castle: Recommendations for the use of human papillomavirus vaccines. UpToDate ONLINE 18.3: 2010. … \u7d9a\u304d\u3092\u8aad\u3080 HPV\u30ef\u30af\u30c1\u30f3\u306e\u6709\u52b9\u6027\u3068\u8cbb\u7528\u5bfe\u52b9\u679c<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[5],"tags":[],"class_list":["post-668","post","type-post","status-publish","format-standard","hentry","category-5"],"_links":{"self":[{"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/posts\/668","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=668"}],"version-history":[{"count":1,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/posts\/668\/revisions"}],"predecessor-version":[{"id":669,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/posts\/668\/revisions\/669"}],"wp:attachment":[{"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=668"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=668"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=668"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}