{"id":876,"date":"2015-10-07T15:54:02","date_gmt":"2015-10-07T06:54:02","guid":{"rendered":"http:\/\/www.hcfm.jp\/journal\/?p=876"},"modified":"2015-10-07T15:54:02","modified_gmt":"2015-10-07T06:54:02","slug":"%e9%a2%a8%e9%82%aa%e3%81%a8%e3%83%97%e3%83%a9%e3%82%bb%e3%83%9c%e5%8a%b9%e6%9e%9c","status":"publish","type":"post","link":"https:\/\/www.hcfm.jp\/journal\/?p=876","title":{"rendered":"\u98a8\u90aa\u3068\u30d7\u30e9\u30bb\u30dc\u52b9\u679c"},"content":{"rendered":"<p>\u2015\u6587\u732e\u540d\u2015<br \/>\nBarrett B, Brown R, et al. Placebo Effects and the Common Cold: A Randomized Controlled Trial. Ann Fam Med 2011;312-322.<\/p>\n<p>\u2015\u3053\u306e\u6587\u732e\u3092\u9078\u3093\u3060\u80cc\u666f\u2015<br \/>\n\u3000\u4f1d\u7d71\u7684\u306b\u4f7f\u7528\u3055\u308c\u3066\u304d\u305f\u5bfe\u75c7\u7642\u6cd5\u85ac\u306e\u591a\u304f\u304c\u75c7\u72b6\u306e\u7de9\u548c\u3084\u6709\u75c5\u671f\u9593\u3092\u77ed\u304f\u3059\u308b\u52b9\u679c\u304c\u306a\u3044\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u308b\u3002\u4eca\u56de\u3001\u7c73\u56fd\u3067\u4f1d\u7d71\u7684\u306b\u4f7f\u7528\u3055\u308c\u3066\u3044\u308b\u5bfe\u75c7\u7642\u6cd5\u85acEchinacea\uff08Cochrane\u306e\u30b7\u30b9\u30c6\u30de\u30c6\u30a3\u30c3\u30af\u30ec\u30d3\u30e5\u30fc1\uff09\u3067\u30d7\u30e9\u30bb\u30dc\u3068\u6709\u610f\u5dee\u304c\u306a\u304b\u3063\u305f\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u308b\uff09\u3092\u30aa\u30fc\u30d7\u30f3\u30e9\u30d9\u30eb\u3068\u3057\u305f\u3068\u304d\u306e\u52b9\u679c\u3092\u76f2\u691c\u5316\u3057\u305f\u3068\u304d\u3068\u6bd4\u8f03\u3057\u305f\u7814\u7a76\u3092\u5c0f\u5150\u306e\u98a8\u90aa\u306b\u95a2\u3059\u308b\u7dcf\u8aac\u3092\u57f7\u7b46\u4e2d\u306b\u898b\u3064\u3051\u3001\u7d50\u679c\u304c\u8208\u5473\u6df1\u304b\u3063\u305f\u306e\u3067\u7d39\u4ecb\u3059\u308b\u3002<br \/>\n<em>1\uff09Linde K, Barrett B, W\u00f6lkart K, Bauer R, Melchart D. Echinacea for pre- venting and treating the common cold. Cochrane Database Syst Rev. 2006;(1):CD000530.<\/em><\/p>\n<p>\u2015\u8981\u7d04\u2015<br \/>\n\u3010\u76ee\u7684\u3011<br \/>\n\u3000\u30aa\u30fc\u30d7\u30f3\u30e9\u30d9\u30eb\u5316\u3057\u305f\u85ac\u5264\u3092\u30e9\u30f3\u30c0\u30e0\u306b\u5272\u308a\u4ed8\u3051\u305f\u5834\u5408\u3001\u4e8c\u91cd\u76f2\u691c\u5316\u3057\u5b9f\u85ac\u3068\u30d7\u30e9\u30bb\u30dc\u306b\u5272\u308a\u4ed8\u3051\u305f\u5834\u5408\u3001\u4f55\u3082\u85ac\u5264\u3092\u51e6\u65b9\u3057\u306a\u3044\u5834\u5408\u306e3\u8005\u3092\u6bd4\u8f03\u3057\u305f\u5834\u5408\u3001\u98a8\u90aa\u306b\u3088\u308b\u75c7\u72b6\u306e\u91cd\u3055\u3084\u671f\u9593\u304c\u5909\u308f\u308b\u304b\u3069\u3046\u304b\u3092\u8abf\u3079\u308b\u3002<\/p>\n<p>\u3010\u65b9\u6cd5\u3011<br \/>\n\u3000\u65b0\u898f\u767a\u75c7\u306e\u98a8\u90aa\u60a3\u8005\u3067RCT\u3092\u884c\u3063\u305f\u3002\u53c2\u52a0\u8005\u306f4\u30b0\u30eb\u30fc\u30d7\uff08Figure1\uff0c\uff08\uff11\uff09\u85ac\u5264\u306a\u3057\uff0c\uff08\uff12\uff09\u76f2\u691c\u5316\u3055\u308c\u305f\u30d7\u30e9\u30bb\u30dc\uff0c\uff08\uff13\uff09\u76f2\u691c\u5316\u3055\u308c\u305fechinacea\uff08\uff14\uff09\u30aa\u30fc\u30d7\u30f3\u30e9\u30d9\u30eb\u306eechinacea\uff09\u306b\u5272\u308a\u4ed8\u3051\u3089\u308c\u305f\u3002\u4e3b\u8981\u30a2\u30a6\u30c8\u30ab\u30e0\u306f\u6709\u75c5\u671f\u9593\u3068area-under-the-curve global severity\u3001\u4e8c\u6b21\u30a2\u30a6\u30c8\u30ab\u30e0\u306f\u5185\u670d2\u65e5\u5f8c\u306e\u9f3b\u8154\u6d17\u6d44\u6db2\u306e\u597d\u4e2d\u7403\u6570\u3068IL8\u30ec\u30d9\u30eb\u3068\u3057\u305f\u3002<\/p>\n<p>\u3010\u7d50\u679c\u3011<br \/>\n\u3000719\u306e\u53c2\u52a0\u8005\u306e\u3046\u30616\u540d\u304c\u96e2\u8131\u3057\u305f\u3002\u5973\u6027\u304c64\uff05\uff0c\u767d\u4eba\u304c88\uff05\u3001\u5e74\u9f62\u306f12\u6b73\u304b\u308980\u6b73\u3002<br \/>\n\u25cb \u6709\u75c5\u671f\u9593\u306e\u5e73\u5747<br \/>\n\u30007.03\u65e5\uff08\u85ac\u5264\u306a\u3057\uff09\uff0c6.87\u65e5\uff08\u76f2\u691c\u5316\u30d7\u30e9\u30bb\u30dc\uff09\uff0c6.34\uff08\u76f2\u691c\u5316echinacea\uff09,6.76\uff08\u30aa\u30fc\u30d7\u30f3\u30e9\u30d9\u30ebechinacea\uff09\u3001<br \/>\n\u3000\u30b0\u30eb\u30fc\u30d7\u9593\u306e\u6bd4\u8f03\u3067\u306f\u7d71\u8a08\u5b66\u7684\u306b\u6709\u610f\u5dee\u306a\u3057<br \/>\n\u25cb global severity\u30b9\u30b3\u30a2\u306e\u5e73\u5747<br \/>\n\u3000286\uff08\u85ac\u5264\u306a\u3057\uff09\uff0c264\uff08\u76f2\u691c\u5316\u30d7\u30e9\u30bb\u30dc\uff09\uff0c236\uff08\u76f2\u691c\u5316echinacea\uff09\uff0c258\uff08\u30aa\u30fc\u30d7\u30f3\u30e9\u30d9\u30ebechinacea\uff09\u3001<br \/>\n\u3000\u30b0\u30eb\u30fc\u30d7\u9593\u306e\u6bd4\u8f03\u3067\u306f\u7d71\u8a08\u5b66\u7684\u306b\u6709\u610f\u5dee\u306a\u3057\u3002<br \/>\n\u3000\u3000\u203b \u85ac\u5264\u306a\u3057\u3068\u76f2\u691c\u5316\u3057\u305f\u30d7\u30e9\u30bb\u30dc\u30b0\u30eb\u30fc\u30d7\u306e\u6bd4\u8f03<br \/>\n\u3000\u3000\u3000\u3000\u6709\u75c5\u671f\u9593 -0.16\u65e5\uff0895%CI -0.90 \u2212 0.58\uff09 severity -22\u30dd\u30a4\u30f3\u30c8\uff0895%CI -70 \u2212 26\uff09<br \/>\n\u3000\u3000\u203b \u76f2\u691c\u5316echinacea\u3068\u30aa\u30fc\u30d7\u30f3\u30e9\u30d9\u30ebechinacea\u30b0\u30eb\u30fc\u30d7\u306e\u6bd4\u8f03<br \/>\n\u3000\u3000\u3000\u3000\u6709\u75c5\u671f\u9593 0.42\u65e5\uff0895%CI -0.28 \u2212 1.12\uff09 severity 22\u30dd\u30a4\u30f3\u30c8\uff0895%CI -19 \u2212 63\uff09<br \/>\n\u25cb IL\uff18\u3068\u597d\u4e2d\u7403\u6570\u306e\u5909\u5316\u306e\u4e2d\u592e\u5024<br \/>\n\u300030pg\/ml\/1cell\uff08\u85ac\u5264\u306a\u3057\uff09\uff0c39pg\/ml\/1cell\uff08\u76f2\u691c\u5316\u30d7\u30e9\u30bb\u30dc\uff09\uff0c58pg\/ml\/2cell\uff08\u76f2\u691c\u5316echinacea\uff09\uff0c<br \/>\n\u300070pg\/ml\/1cell\uff08\u30aa\u30fc\u30d7\u30f3\u30e9\u30d9\u30ebechinacea\uff09\u3002<br \/>\n\u3000\u30b0\u30eb\u30fc\u30d7\u9593\u306e\u6bd4\u8f03\u3067\u306f\u7d71\u8a08\u5b66\u7684\u306b\u6709\u610f\u5dee\u306a\u3057\u3002<br \/>\n\u25cb \u85ac\u5264\u306e\u670d\u7528\u6642\u306bechinacea\u306e\u6709\u52b9\u6027\u3092\u9ad8\u304f\u898b\u7a4d\u3082\u3063\u305f\uff08100\u70b9\u3092\u300c\u304d\u308f\u3081\u3066\u6709\u52b9\u300d\u3068\u3059\u308b\u30b9\u30b1\u30fc\u30eb\u306750\u70b9\u4ee5\u4e0a\u3092\u3064\u3051\u305f\uff09<br \/>\n\u3000120\u306e\u53c2\u52a0\u8005\u306b\u304a\u3044\u3066\u76f2\u691c\u5316\u3055\u308c\u305f\u30d7\u30e9\u30bb\u30dc\u7fa4\u306f\u85ac\u5264\u306a\u3057\u306e\u7fa4\u3068\u6bd4\u8f03\u3057\u3066\u6709\u75c5\u671f\u9593\u306f2.58\u65e5\u6709\u610f\u306b\u77ed\u304f\uff0895%CI -4.47 \u2212 -0.68\uff09\u3001<br \/>\n\u3000global sevirty\u30b9\u30b3\u30a2\u306e\u5e73\u5747\u306f26\uff05\u4f4e\u304b\u3063\u305f\uff08\u221297\uff0c95%CI \u2212249.8 \u2013 55.8 \u6709\u610f\u5dee\u306a\u3057\uff09\u3002<br \/>\n\u3000\u3053\u306e\u30b5\u30d6\u30b0\u30eb\u30fc\u30d7\u306b\u304a\u3044\u3066\u306f\u76f2\u691c\u5316echinacea\u7fa4\u3068\u30aa\u30fc\u30d7\u30f3\u30e9\u30d9\u30eb\u306eechinacea\u7fa4\u3067\u6bd4\u8f03\u3059\u308b\u3068\u6709\u75c5\u671f\u9593\u3082\u91cd\u75c7\u5ea6\u3082\u9055\u3044\u306f\u306a\u304b\u3063\u305f\u3002<\/p>\n<p>\u3010\u7d50\u8ad6\u3011<br \/>\n\u3000\u85ac\u5264\u306a\u3057\u7fa4\u306b\u5272\u308a\u4ed8\u3051\u3089\u308c\u305f\u7fa4\u3067\u306f\u6709\u75c5\u671f\u9593\u304c\u9577\u304f\u306a\u308a\u3001\u75c7\u72b6\u304c\u91cd\u304f\u306a\u308b\u50be\u5411\u304c\u3042\u3063\u305f\uff08\u7d71\u8a08\u5b66\u7684\u6709\u610f\u5dee\u306f\u306a\u3044\uff09\u3002<br \/>\n\u3000Echinacea\u306e\u6709\u52b9\u6027\u3092\u4fe1\u3058\u3066\u3044\u308b\u30b5\u30d6\u30b0\u30eb\u30fc\u30d7\u3067\u85ac\u5264\u3092\u4e0e\u3048\u3089\u308c\u305f\u30b0\u30eb\u30fc\u30d7\u3067\u306f\u6709\u75c5\u671f\u9593\u304c\u77ed\u304f\u306a\u308a\u3001\u75c7\u72b6\u304c\u8efd\u304f\u306a\u308b\u50be\u5411\u304c\u3042\u3063\u305f\u3002<br \/>\n\u3000\u3053\u308c\u3089\u306e\u7d50\u679c\u306f\u3001\u60a3\u8005\u306e\u6cbb\u7642\u306b\u5bfe\u3059\u308b\u4fe1\u5ff5\u3084\u611f\u3058\u65b9\u304c\u91cd\u8981\u3067\u3042\u308a\u3001\u533b\u7642\u306b\u304a\u3051\u308b\u610f\u5fd7\u6c7a\u5b9a\u306b\u304a\u3044\u3066\u306f\u8003\u616e\u3055\u308c\u308b\u3079\u304d\u3067\u3042\u308b\u3068\u3044\u3046\u8003\u3048\u65b9\u3092\u652f\u6301\u3059\u308b\u3082\u306e\u3067\u3042\u3063\u305f\u3002<\/p>\n<p>\u3010\u958b\u50ac\u65e5\u3011<br \/>\n2015\u5e7410\u67087\u65e5\uff08\u6c34\uff09<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u2015\u6587\u732e\u540d\u2015 Barrett B, Brown R, et al. Placebo Effects and the Common Cold: A Randomized Controlled Trial. Ann Fam M &hellip; <a href=\"https:\/\/www.hcfm.jp\/journal\/?p=876\" class=\"more-link\">\u7d9a\u304d\u3092\u8aad\u3080 <span class=\"screen-reader-text\">\u98a8\u90aa\u3068\u30d7\u30e9\u30bb\u30dc\u52b9\u679c<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[17],"tags":[],"class_list":["post-876","post","type-post","status-publish","format-standard","hentry","category-17"],"_links":{"self":[{"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/posts\/876","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=876"}],"version-history":[{"count":6,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/posts\/876\/revisions"}],"predecessor-version":[{"id":882,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=\/wp\/v2\/posts\/876\/revisions\/882"}],"wp:attachment":[{"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=876"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=876"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hcfm.jp\/journal\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=876"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}